Shear Wave Elastography Assessment of Carotid Plaque Stiffness: In Vitro Reproducibility Study

2014 ◽  
Vol 40 (1) ◽  
pp. 200-209 ◽  
Author(s):  
Kumar V. Ramnarine ◽  
James W. Garrard ◽  
Katie Dexter ◽  
Sarah Nduwayo ◽  
Ronney B. Panerai ◽  
...  
Keyword(s):  
Shear Wave ◽  
Carotid Plaque ◽  
Shear Wave Elastography ◽  
Reproducibility Study

scholarly journals Ultrasound Elastography: another piece in the puzzle of carotid plaque vulnerability?

2021 ◽  
Author(s):  
Andjoli Davidhi ◽  
Vasileios Rafailidis ◽  
Evangelos Destanis ◽  
Panos Prassopoulos ◽  
Stefanos Foinitsis
Keyword(s):  
Shear Wave ◽  
Carotid Plaque ◽  
Diagnostic Yield ◽  
Imaging Modality ◽  
Shear Wave Elastography ◽  
Ultrasound Elastography ◽  
Intraplaque Hemorrhage ◽  
Plaque Vulnerability ◽  
Carotid Plaques ◽  
Increased Risk

Recent literature has shown that various carotid plaque features, other than stenosis, contribute to plaque vulnerability. Features such as surface morphology and plaque composition with distinct components (e.g. intraplaque hemorrhage, lipid core) have been associated with the increased risk of future cerebrovascular events. Ultrasonography constitutes the first line modality for the assessment of carotid disease and has traditionally been used to grade stenosis with high accuracy. Recenttechnological advances such as contrast-enhanced ultrasound and elastography increased the diagnostic yield of ultrasound in assessing the morphology of carotid plaques. The purpose of this review is to present the available literature on ultrasound elastography of the atherosclerotic carotid. Strain and shear wave elastography allow for the characterization of plaque components, thus indicating its nature and importantly, the plaque’s vulnerability. Shear wave elastography indices appear morerobust than Strain indices. Overall, elastography is a feasible method to distinguish vulnerable carotid plaques. There is, however, a need for larger and longer prospective controlled clinical studies in order to validate elastography as an imaging modality used for the detection of unstable carotid plaques.

scholarly journals Plaque characterization using shear wave elastography—evaluation of differentiability and accuracy using a combined ex vivo and in vitro setup

2018 ◽  
Vol 63 (23) ◽  
pp. 235008 ◽  
Author(s):  
David Marlevi ◽  
Elira Maksuti ◽  
Matthew W Urban ◽  
Reidar Winter ◽  
Matilda Larsson
Keyword(s):  
Shear Wave ◽  
Ex Vivo ◽  
Shear Wave Elastography ◽  
Plaque Characterization

Shear-Wave Elastography Enables Identification of Unstable Carotid Plaque

2021 ◽  
Author(s):  
David Školoudík ◽  
Petra Kešnerová ◽  
Jaroslav Vomáčka ◽  
Tomáš Hrbáč ◽  
David Netuka ◽  
...  
Keyword(s):  
Shear Wave ◽  
Carotid Plaque ◽  
Shear Wave Elastography

scholarly journals A Cross-Machine Comparison of Shear-Wave Speed Measurements Using 2D Shear-Wave Elastography in the Normal Female Breast

2021 ◽  
Vol 11 (20) ◽  
pp. 9391
Author(s):  
Emma Harris ◽  
Ruchi Sinnatamby ◽  
Elizabeth O’Flynn ◽  
Anna M. Kirby ◽  
Jeffrey C. Bamber
Keyword(s):  
Adipose Tissue ◽  
Shear Wave ◽  
Subcutaneous Adipose Tissue ◽  
Wave Speed ◽  
Shear Wave Elastography ◽  
Shear Wave Speed ◽  
Skin Region ◽  
Subcutaneous Adipose

Quantitative measures of radiation-induced breast stiffness are required to support clinical studies of novel breast radiotherapy regimens and exploration of personalised therapy, however, variation between shear-wave elastography (SWE) machines may limit the usefulness of shear-wave speed (cs) for this purpose. Mean cs measured in four healthy volunteers’ breasts and a phantom using 2D-SWE machines Acuson S2000 (Siemens Medical Solutions) and Aixplorer (Supersonic Imagine) were compared. Shear-wave speed was measured in the skin region, subcutaneous adipose tissue and parenchyma. cs estimates were on average 2.3% greater when using the Aixplorer compared to S2000 in vitro. In vivo, cs estimates were on average 43.7%, 36.3% and 49.9% significantly greater (p << 0.01) when using the Aixplorer compared to S2000, for skin region, subcutaneous adipose tissue and parenchyma, respectively. In conclusion, despite relatively small differences between machines observed in vitro, large differences in absolute measures of shear wave speed measured were observed in vivo, which may prevent pooling of cross-machine data in clinical studies of the breast.

scholarly journals Intervertebral disc characterization by shear wave elastography: An in vitro preliminary study

2014 ◽  
Vol 228 (6) ◽  
pp. 607-615 ◽  
Author(s):  
Claudio Vergari ◽  
Philippe Rouch ◽  
Guillaume Dubois ◽  
Dominique Bonneau ◽  
Jean Dubousset ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Preliminary Study

scholarly journals Intra- and inter-observer variation and accuracy using different shear wave elastography methods to assess circumscribed objects – a phantom study.

2017 ◽  
Vol 19 (4) ◽  
pp. 357 ◽  
Author(s):  
Gregor Seliger ◽  
Katharina Chaoui ◽  
Christian Kunze ◽  
Yasmina Dridi ◽  
Klaus-Vitold Jenderka ◽  
...  
Keyword(s):  
Shear Wave ◽  
Elastic Properties ◽  
Measurement Techniques ◽  
Intraclass Correlation ◽  
Shear Wave Elastography ◽  
Observer Variation ◽  
Significant Difference ◽  
Clinical Interest ◽  
Observational Errors

Aims: The elastic properties of circumscribed tissues (e.g., tendons, lymph nodes, prostates, brain tumors) are of considerable clinical interest. The purpose of this study was thus to compare the Intra-/Inter-observer variation and accuracy in vitro of point shear wave elastography (pSWE) with that of 2D-SWE and to assess 2D-SWE’s precision with variable ROI (vROI) incircumscribed objects.Material and methods: Round targets (Elasticity QA Phantom Model 049) were examined for varying degrees of stiffness (8, 14, 45, and 80 kPa) and diameters (20/10 mm). Three ultrasound systems and four probes were applied (pSWE: Acuson/S3000 9L4/4C1 and Epiq7 C51, 2D-SWE: Aplio/500 PVT375BT). Three different ROIs were used, namely fixed ROI (fROI) and variable ROI: rectangular-best-fitted ROI, and round-best-fitted ROI. Each measurement was performed twice by four observers.Results: A total of 3,604 measurements were conducted. The intra-observer variation of 2D-SWE measurements indicated better agreement (Intraclass Correlation Coefficient (ICC) = 0.971; 95% CI=[0.945; 0.985]), than for the pSWE measurements (ICC = 0.872; 95% CI=[0.794; 0.92]). With both methods, the shear wave elastography applied showed low inter-observer variation: ICC = 0.980; 95% CI=[0.970; 0.987]. However, a significant difference was observed between fROI (pSWE) and vROI (2D-SWE) on circumscribed objects in terms of accuracy. The lowest degree of observationerror was detected in situations where the ROI was not “best fitted”, but placed within the target of 3mm from the border (target diameter: 20mm; mean relative error = 0.15).Conclusions: When estimating the elastic properties of circumscribed tissues, the different measurement techniques performed by commercial shear wave elastography systems reveal a strong susceptibility for observational errors, depending upon the fixed vs. variable ROI of the pSWE vs. 2D-SWE technique.

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