Safety and immunogenicity of attenuated Salmonella enterica serovar Typhimurium delivering an HIV-1 Gag antigen via the Salmonella Type III secretion system

Vaccine ◽  
2006 ◽  
Vol 24 (37-39) ◽  
pp. 6216-6224 ◽  
Author(s):  
Camille N. Kotton ◽  
Alexander J. Lankowski ◽  
Nathaniel Scott ◽  
David Sisul ◽  
Li Mei Chen ◽  
...  
Keyword(s):  
Type Iii Secretion ◽  
Salmonella Enterica ◽  
Salmonella Enterica Serovar Typhimurium ◽  
Type Iii Secretion System ◽  
Secretion System ◽  
Type Iii ◽  
Serovar Typhimurium ◽  
Hiv 1

TolC, but not AcrB, is involved in the invasiveness of multidrug-resistant Salmonella enterica serovar Typhimurium by increasing type III secretion system-1 expression

2008 ◽  
Vol 298 (7-8) ◽  
pp. 561-569 ◽  
Author(s):  
Isabelle Virlogeux-Payant ◽  
Sylvie Baucheron ◽  
Julien Pelet ◽  
Jérôme Trotereau ◽  
Elisabeth Bottreau ◽  
...  
Keyword(s):  
Type Iii Secretion ◽  
Salmonella Enterica ◽  
Salmonella Enterica Serovar Typhimurium ◽  
Type Iii Secretion System ◽  
Multidrug Resistant ◽  
Secretion System ◽  
Type Iii ◽  
Serovar Typhimurium ◽  
System 1

scholarly journals SigE Is a Chaperone for the Salmonella enterica Serovar Typhimurium Invasion Protein SigD

2001 ◽  
Vol 183 (4) ◽  
pp. 1452-1454 ◽  
Author(s):  
K. Heran Darwin ◽  
Lloyd S. Robinson ◽  
Virginia L. Miller
Keyword(s):  
Hybrid System ◽  
Type Iii Secretion ◽  
Salmonella Enterica ◽  
Salmonella Enterica Serovar Typhimurium ◽  
Type Iii Secretion System ◽  
Secretion System ◽  
Type Iii ◽  
Serovar Typhimurium ◽  
Two Hybrid

ABSTRACT SigD is translocated into eucaryotic cells by a type III secretion system. In this work, evidence that the putative chaperone SigE directly interacts with SigD is presented. A bacterial two-hybrid system demonstrated that SigE can interact with itself and SigD. In addition, SigD was specifically copurified with SigE-His6on a nickel column.

scholarly journals InvB Is Required for Type III-Dependent Secretion of SopA in Salmonella enterica Serovar Typhimurium

2004 ◽  
Vol 186 (4) ◽  
pp. 1215-1219 ◽  
Author(s):  
Kristin Ehrbar ◽  
Siegfried Hapfelmeier ◽  
Bärbel Stecher ◽  
Wolf-Dietrich Hardt
Keyword(s):  
Type Iii Secretion ◽  
Salmonella Enterica ◽  
Salmonella Enterica Serovar Typhimurium ◽  
Type Iii Secretion System ◽  
Secretion System ◽  
Host Cells ◽  
Effector Protein ◽  
Enteric Disease ◽  
Type Iii ◽  
Serovar Typhimurium

ABSTRACT The Salmonella effector protein SopA is translocated into host cells via the SPI-1 type III secretion system (TTSS) and contributes to enteric disease. We found that the chaperone InvB binds to SopA and slightly stabilizes it in the bacterial cytosol and that it is required for its transport via the SPI-1 TTSS.

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