Cost-effectiveness of rabies post-exposure prophylaxis in the context of very low rabies risk: A decision-tree model based on the experience of France

Vaccine ◽  
2015 ◽  
Vol 33 (20) ◽  
pp. 2367-2378 ◽  
Author(s):  
Florence Ribadeau Dumas ◽  
Dieynaba S. N’Diaye ◽  
Juliette Paireau ◽  
Philippe Gautret ◽  
Hervé Bourhy ◽  
...  
HIV Medicine ◽  
2009 ◽  
Vol 10 (4) ◽  
pp. 199-208 ◽  
Author(s):  
D Guinot ◽  
MT Ho ◽  
IM Poynten ◽  
J McAllister ◽  
A Pierce ◽  
...  

2018 ◽  
Vol 41 (2) ◽  
pp. 379-390
Author(s):  
Sudhir Venkatesan ◽  
Cristina Carias ◽  
Matthew Biggerstaff ◽  
Angela P Campbell ◽  
Jonathan S Nguyen-Van-Tam ◽  
...  

Abstract Background Many countries have acquired antiviral stockpiles for pandemic influenza mitigation and a significant part of the stockpile may be focussed towards community-based treatment. Methods We developed a spreadsheet-based, decision tree model to assess outcomes averted and cost-effectiveness of antiviral treatment for outpatient use from the perspective of the healthcare payer in the UK. We defined five pandemic scenarios—one based on the 2009 A(H1N1) pandemic and four hypothetical scenarios varying in measures of transmissibility and severity. Results Community-based antiviral treatment was estimated to avert 14–23% of hospitalizations in an overall population of 62.28 million. Higher proportions of averted outcomes were seen in patients with high-risk conditions, when compared to non-high-risk patients. We found that antiviral treatment was cost-saving across pandemic scenarios for high-risk population groups, and cost-saving for the overall population in higher severity influenza pandemics. Antiviral effectiveness had the greatest influence on both the number of hospitalizations averted and on cost-effectiveness. Conclusions This analysis shows that across pandemic scenarios, antiviral treatment can be cost-saving for population groups at high risk of influenza-related complications.


BMC Urology ◽  
2011 ◽  
Vol 11 (1) ◽  
Author(s):  
Salvador Arlandis-Guzman ◽  
Carlos Errando-Smet ◽  
Jeffrey Trocio ◽  
Daniel Arumi ◽  
Javier Rejas

Vaccine ◽  
2008 ◽  
Vol 26 (33) ◽  
pp. 4251-4255 ◽  
Author(s):  
Praveen Dhankhar ◽  
Sagar A. Vaidya ◽  
Daniel B. Fishbien ◽  
Martin I. Meltzer

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