Relative contribution of porcine reproductive and respiratory syndrome virus open reading frames 2–4 to the induction of protective immunity

Vaccine ◽  
2017 ◽  
Vol 35 (34) ◽  
pp. 4408-4413 ◽  
Author(s):  
Kathryn Kimpston-Burkgren ◽  
Ignacio Correas ◽  
Fernando A. Osorio ◽  
David Steffen ◽  
Asit K. Pattnaik ◽  
...  
Keyword(s):  
Protective Immunity ◽  
Open Reading Frames ◽  
Respiratory Syndrome Virus ◽  
Relative Contribution ◽  
Reading Frames

scholarly journals Complete Genome Sequence of an NADC30-Like Porcine Reproductive and Respiratory Syndrome Virus Characterized by Recombination with Other Strains

2016 ◽  
Vol 4 (3) ◽  
Author(s):  
Yingying Li ◽  
Guobiao Ji ◽  
Juan Wang ◽  
Feifei Tan ◽  
Jinshan Zhuang ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Open Reading Frames ◽  
Respiratory Syndrome Virus ◽  
Reading Frames

We report here the complete genome sequence of an NADC30-like porcine reproductive and respiratory syndrome virus (PRRSV), HNyc15, which was characterized by recombination with VR-2332 and CH-1a PRRSV strains in open reading frames (ORFs) 2 to 4.

Porcine bocaviruses: genetic analysis and prevalence in Chinese swine population

2011 ◽  
Vol 139 (10) ◽  
pp. 1581-1586 ◽  
Author(s):  
H. B. ZHANG ◽  
L. HUANG ◽  
Y. J. LIU ◽  
T. LIN ◽  
C. Q. SUN ◽  
...  
Keyword(s):  
Porcine Circovirus Type ◽  
Open Reading Frames ◽  
Porcine Circovirus ◽  
Respiratory Syndrome Virus ◽  
Mixed Infections ◽  
Detection Rates ◽  
Swine Population ◽  
Swine Herds ◽  
Reading Frames

SUMMARYIn members of theBocavirusgenus, that contain three open reading frames (ORFs) of the Parvovirinae subfamily, porcine bocaviruses (PoBoVs) exhibit the most genetic diversity. Based on the ORF2-encoded viral protein (VP1) classification, the six reported porcine bocaviruses were grouped into four species: PoBoV1 (porcine boca-like virus or PBoLV), PoBoV2 (porcine parvovirus 4 or PPV4), PoBoV3 (PBoV1/PBoV2) and PoBoV4 (6V/7V), with PoBoV3 and PoBoV4 each having two genotype viruses. All four PoBoV species were detected in the 166 samples collected in 2010 from swine herds located in ten provinces of China. The detection rates for PoBoV1-4 were 28·9%, 6·6%, 19·3% and 39·7%, respectively. The co-infection combinations involving these six porcine bocaviruses in the collected samples were very complex. Furthermore, mixed infections with viruses from other families (porcine reproductive and respiratory syndrome virus, classic swine fever virus and porcine circovirus type 2) were also detected.

scholarly journals Molecular and Genetic Characterization of a Novel Nisin Variant Produced by Streptococcus uberis

2006 ◽  
Vol 72 (2) ◽  
pp. 1148-1156 ◽  
Author(s):  
Ruth E. Wirawan ◽  
Nikolai A. Klesse ◽  
Ralph W. Jack ◽  
John R. Tagg
Keyword(s):  
Protective Immunity ◽  
Sequence Similarity ◽  
Bovine Mastitis ◽  
Open Reading Frames ◽  
Cross Resistance ◽  
Producer Strain ◽  
Streptococcus Uberis ◽  
Causative Agents ◽  
Reading Frames

ABSTRACT Streptococcus uberis is one of the principal causative agents of bovine mastitis. In this study, we report that S. uberis strain 42 produces a lantibiotic, nisin U, which is 78% identical (82% similar) to nisin A from Lactococcus lactis. The 15.6-kb nisin U locus comprises 11 open reading frames, similar in putative functionality but differing in arrangement from that of the nisin A biosynthetic cluster. The nisin U producer strain exhibits specific resistance (immunity) to nisin U and cross-resistance to nisin A, a finding consistent with the 55% sequence similarity of their respective immunity peptides. Homologues of the nisin U structural gene were identified in several additional S. uberis strains, and in each case cross-protective immunity was expressed to nisin A and to the other producers of nisin U and its variants. To our knowledge, this is the first report both of characterization of a bacteriocin by S. uberis, as well as of a member of the nisin family of peptides in a species other than L. lactis.

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