scholarly journals Relative quantitative kinetics of interferon-gamma and interleukin-10 mRNA and protein production by activated ovine peripheral blood mononuclear cells

2010 ◽  
Vol 136 (1-2) ◽  
pp. 34-42 ◽  
Author(s):  
S.R. Wattegedera ◽  
D.M. Watson ◽  
J.C. Hope ◽  
P. Kaiser ◽  
J. Sales ◽  
...  
2002 ◽  
Vol 20 (6) ◽  
pp. 543-550 ◽  
Author(s):  
Mary C. Perianayagam ◽  
Bertrand L. Jaber ◽  
Daqing Guo ◽  
Andrew J. King ◽  
Brian J.G. Pereira ◽  
...  

1998 ◽  
Vol 66 (12) ◽  
pp. 6058-6062 ◽  
Author(s):  
Minja Miettinen ◽  
Sampsa Matikainen ◽  
Jaana Vuopio-Varkila ◽  
Jaana Pirhonen ◽  
Kari Varkila ◽  
...  

ABSTRACT Human peripheral blood mononuclear cells (PBMC) were stimulated with three nonpathogenic Lactobacillus strains and with one pathogenic Streptococcus pyogenes strain, and cytokine gene expression and protein production were analyzed. All bacteria strongly induced interleukin-1β (IL-1β), IL-6, and tumor necrosis factor alpha mRNA expression and protein production. S. pyogenes was the most potent inducer of secretion of IL-12 and gamma interferon (IFN-γ), and two of three Lactobacillusstrains induced IL-12 and IFN-γ production. All strains induced IL-18 protein production. IL-10 and IL-4 production was induced weakly and not at all, respectively. Our data show that nonpathogenic lactobacilli and pathogenic streptococci can induce Th1 type cytokines IL-12, IL-18, and IFN-γ in human PBMC.


Author(s):  
Carolina Valadares Nunes ◽  
Laila Rigolin Fortunato ◽  
Jhony Robison Oliveira ◽  
Aline Beatriz Mahler Pereira ◽  
Gabriela Rister Figueiredo Irie ◽  
...  

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