Homoharringtonine potentiates the antileukemic activity of arsenic trioxide against acute myeloid leukemia cells

Experimental Cell Research ◽

10.1016/j.yexcr.2019.02.008 ◽

2019 ◽

Vol 376 (2) ◽

pp. 114-123 ◽

Author(s):

Ping Chen ◽

Weiwu Zhan ◽

Bin Wang ◽

Peidong You ◽

Qing Jin ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Antileukemic Activity ◽

Acute Myeloid Leukemia Cells ◽

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Downregulation of Mcl-1 through GSK-3β activation contributes to arsenic trioxide-induced apoptosis in acute myeloid leukemia cells

Leukemia ◽

10.1038/leu.2012.180 ◽

2012 ◽

Vol 27 (2) ◽

pp. 315-324 ◽

Author(s):

R Wang ◽

L Xia ◽

J Gabrilove ◽

S Waxman ◽

Y Jing

Keyword(s):

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Acute Myeloid Leukemia Cells ◽

Gsk 3Β ◽

Induced Apoptosis ◽

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Low-dose 1,25-dihydroxyvitamin D3 combined with arsenic trioxide synergistically inhibits proliferation of acute myeloid leukemia cells by promoting apoptosis

Oncology Reports ◽

10.3892/or.2013.2444 ◽

2013 ◽

Vol 30 (1) ◽

pp. 485-491 ◽

Author(s):

JI-YEON BAE ◽

JI-WON KIM ◽

INHO KIM

Keyword(s):

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Low Dose ◽

Leukemia Cells ◽

Dihydroxyvitamin D3 ◽

1,25 Dihydroxyvitamin D3 ◽

Acute Myeloid Leukemia Cells ◽

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Azacytidine sensitizes acute myeloid leukemia cells to arsenic trioxide by up-regulating the arsenic transporter aquaglyceroporin 9

Journal of Hematology & Oncology ◽

10.1186/s13045-015-0143-3 ◽

2015 ◽

Vol 8 (1) ◽

Author(s):

David Chau ◽

Karen Ng ◽

Thomas Sau-Yan Chan ◽

Yuen-Yee Cheng ◽

Bonnie Fong ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Acute Myeloid Leukemia Cells ◽

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Arsenic Trioxide and Sorafenib Induce Synthetic Lethality of FLT3-ITD Acute Myeloid Leukemia Cells

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-17-0298 ◽

2018 ◽

Vol 17 (9) ◽

pp. 1871-1880 ◽

Author(s):

Rui Wang ◽

Ying Li ◽

Ping Gong ◽

Janice Gabrilove ◽

Samuel Waxman ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Synthetic Lethality ◽

Leukemia Cells ◽

Acute Myeloid Leukemia Cells ◽

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Abstract 5479: Mcl-1 is differentially regulated in acute myeloid leukemia cells treated with all trans retinoic acid and arsenic trioxide

10.1158/1538-7445.am2011-5479 ◽

2011 ◽

Author(s):

Rui Wang ◽

Samuel Waxman ◽

Yongkui Jing

Keyword(s):

Acute Myeloid Leukemia ◽

Retinoic Acid ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid ◽

Acute Myeloid Leukemia Cells ◽

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Blockade of JAK2/STAT3 intensifies the anti-tumor activity of arsenic trioxide in acute myeloid leukemia cells: Novel synergistic mechanism via the mediation of reactive oxygen species

European Journal of Pharmacology ◽

10.1016/j.ejphar.2018.07.010 ◽

2018 ◽

Vol 834 ◽

pp. 65-76 ◽

Author(s):

Yashar Mesbahi ◽

Ali Zekri ◽

Seyed H. Ghaffari ◽

Parvaneh Sadat Tabatabaie ◽

Shahin Ahmadian ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Oxygen Species ◽

Acute Myeloid Leukemia Cells ◽

Synergistic Mechanism ◽

Anti Tumor Activity ◽

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Combined Antileukemic Activity of pIXY 321 and Ara-C against Human Acute Myeloid Leukemia Cells

Leukemia & Lymphoma ◽

10.3109/10428199409049748 ◽

1994 ◽

Vol 15 (5-6) ◽

pp. 445-451 ◽

Author(s):

Caroline Tang ◽

Yue Huang ◽

Vidya S. Ponnathpur ◽

Swapan Ray ◽

Mary Ella Mahoney ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Antileukemic Activity ◽

Human Acute Myeloid Leukemia ◽

Acute Myeloid Leukemia Cells ◽

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Quizartinib, a selective FLT3 inhibitor, maintains antileukemic activity in preclinical models of RAS-mediated midostaurin-resistant acute myeloid leukemia cells

10.18632/oncotarget.27489 ◽

2020 ◽

Vol 11 (11) ◽

pp. 943-955 ◽

Author(s):

Tomoya Aikawa ◽

Noriko Togashi ◽

Koichi Iwanaga ◽

Hiroyuki Okada ◽

Yumi Nishiya ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Antileukemic Activity ◽

Preclinical Models ◽

Flt3 Inhibitor ◽

Acute Myeloid Leukemia Cells ◽

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Arsenic trioxide induces autophagic degradation of the FLT3-ITD mutated protein in FLT3-ITD acute myeloid leukemia cells

Journal of Cancer ◽

10.7150/jca.29751 ◽

2020 ◽

Vol 11 (12) ◽

pp. 3476-3482

Author(s):

Xiao-Jian Liu ◽

Li-Na Wang ◽

Zu-Han Zhang ◽

Cong Liang ◽

Yu Li ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Acute Myeloid Leukemia Cells ◽

Autophagic Degradation ◽

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BIMELis a key effector molecule in oxidative stress-mediated apoptosis in acute myeloid leukemia cells when combined with arsenic trioxide and buthionine sulfoximine

10.1186/1471-2407-14-27 ◽

2014 ◽

Vol 14 (1) ◽

Author(s):

Yukie Tanaka ◽

Takayuki Komatsu ◽

Hiroko Shigemi ◽

Takahiro Yamauchi ◽

Yutaka Fujii

Keyword(s):

Oxidative Stress ◽

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Buthionine Sulfoximine ◽

Leukemia Cells ◽

Effector Molecule ◽

Acute Myeloid Leukemia Cells ◽

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