Low-dose 1,25-dihydroxyvitamin D3 combined with arsenic trioxide synergistically inhibits proliferation of acute myeloid leukemia cells by promoting apoptosis

1,25-Dihydroxyvitamin D3 Enhances the Apoptotic Activity of MDM2 Antagonist Nutlin-3a in Acute Myeloid Leukemia Cells Expressing Wild-type p53

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-09-1036 ◽

2010 ◽

Vol 9 (5) ◽

pp. 1158-1168 ◽

Cited By ~ 22

Author(s):

Thelma Thompson ◽

Michael Andreeff ◽

George P. Studzinski ◽

Lyubomir T. Vassilev

Keyword(s):

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Wild Type ◽

Dihydroxyvitamin D3 ◽

Mdm2 Antagonist ◽

Apoptotic Activity ◽

Restored expression of vitamin D receptor and sensitivity to 1,25-dihydroxyvitamin D3 in response to disrupted fusion FOP2–FGFR1 gene in acute myeloid leukemia cells

Cell & Bioscience ◽

10.1186/s13578-016-0075-9 ◽

2016 ◽

Vol 6 (1) ◽

Cited By ~ 6

Author(s):

Aleksandra Marchwicka ◽

Aoife Corcoran ◽

Klaudia Berkowska ◽

Ewa Marcinkowska

Keyword(s):

Vitamin D ◽

Acute Myeloid Leukemia ◽

Vitamin D Receptor ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Dihydroxyvitamin D3 ◽

Fgfr1 Gene ◽

Oncoprotein Cot1 represses kinase suppressors of Ras1/2 and 1,25-dihydroxyvitamin D3-induced differentiation of human acute myeloid leukemia cells

Journal of Cellular Physiology ◽

10.1002/jcp.22449 ◽

2011 ◽

Vol 226 (5) ◽

pp. 1232-1240 ◽

Cited By ~ 4

Author(s):

Xuening Wang ◽

George P. Studzinski

Keyword(s):

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Induced Differentiation ◽

Dihydroxyvitamin D3 ◽

Human Acute Myeloid Leukemia ◽

Abstract 596: Low-dose 1,25-dihydroxyvitamin D3combined with arsenic trioxide synergistically inhibits proliferation of acute myeloid leukemia cells by promoting apoptosis.

10.1158/1538-7445.am2013-596 ◽

2013 ◽

Author(s):

Bae Ji-Yeon ◽

Ji-Won Kim ◽

Inho Kim

Keyword(s):

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Low Dose ◽

Leukemia Cells ◽

Downregulation of Mcl-1 through GSK-3β activation contributes to arsenic trioxide-induced apoptosis in acute myeloid leukemia cells

Leukemia ◽

10.1038/leu.2012.180 ◽

2012 ◽

Vol 27 (2) ◽

pp. 315-324 ◽

Cited By ~ 43

Author(s):

R Wang ◽

L Xia ◽

J Gabrilove ◽

S Waxman ◽

Y Jing

Keyword(s):

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Gsk 3Β ◽

Induced Apoptosis ◽

Azacytidine sensitizes acute myeloid leukemia cells to arsenic trioxide by up-regulating the arsenic transporter aquaglyceroporin 9

Journal of Hematology & Oncology ◽

10.1186/s13045-015-0143-3 ◽

2015 ◽

Vol 8 (1) ◽

Cited By ~ 10

Author(s):

David Chau ◽

Karen Ng ◽

Thomas Sau-Yan Chan ◽

Yuen-Yee Cheng ◽

Bonnie Fong ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Arsenic Trioxide and Sorafenib Induce Synthetic Lethality of FLT3-ITD Acute Myeloid Leukemia Cells

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-17-0298 ◽

2018 ◽

Vol 17 (9) ◽

pp. 1871-1880 ◽

Cited By ~ 6

Author(s):

Rui Wang ◽

Ying Li ◽

Ping Gong ◽

Janice Gabrilove ◽

Samuel Waxman ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Synthetic Lethality ◽

Leukemia Cells ◽

Abstract 5479: Mcl-1 is differentially regulated in acute myeloid leukemia cells treated with all trans retinoic acid and arsenic trioxide

10.1158/1538-7445.am2011-5479 ◽

2011 ◽

Author(s):

Rui Wang ◽

Samuel Waxman ◽

Yongkui Jing

Keyword(s):

Acute Myeloid Leukemia ◽

Retinoic Acid ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid ◽

Homoharringtonine potentiates the antileukemic activity of arsenic trioxide against acute myeloid leukemia cells

Experimental Cell Research ◽

10.1016/j.yexcr.2019.02.008 ◽

2019 ◽

Vol 376 (2) ◽

pp. 114-123 ◽

Cited By ~ 1

Author(s):

Ping Chen ◽

Weiwu Zhan ◽

Bin Wang ◽

Peidong You ◽

Qing Jin ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Antileukemic Activity ◽

Blockade of JAK2/STAT3 intensifies the anti-tumor activity of arsenic trioxide in acute myeloid leukemia cells: Novel synergistic mechanism via the mediation of reactive oxygen species

European Journal of Pharmacology ◽

10.1016/j.ejphar.2018.07.010 ◽

2018 ◽

Vol 834 ◽

pp. 65-76 ◽

Cited By ~ 12

Author(s):

Yashar Mesbahi ◽

Ali Zekri ◽

Seyed H. Ghaffari ◽

Parvaneh Sadat Tabatabaie ◽

Shahin Ahmadian ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Oxygen Species ◽

Synergistic Mechanism ◽

Anti Tumor Activity ◽