The anti-apoptotic effects of HMG-CoA reductase inhibitors on vascular endothelial cells is mediated by ASK1 suppression

Vascular Endothelial ◽

Hmg Coa Reductase ◽

Reductase Inhibitors ◽

Coa Reductase ◽

Apoptotic Effects

3.P.216 Effects of HMG-CoA reductase inhibitors (atorvastatin and simvastatin) on the vasoactive pathways mediated by endothelin-1 and nitric oxide in vascular endothelial cells

Atherosclerosis ◽

10.1016/s0021-9150(97)89289-1 ◽

1997 ◽

Vol 134 (1-2) ◽

pp. 243 ◽

Cited By ~ 1

Author(s):

S. Lamas ◽

O. Hernández-Perera ◽

D. Pérez-Sala ◽

J. Navarro-Antolín ◽

R. Sánchez-Pascuala ◽

...

Keyword(s):

Nitric Oxide ◽

Endothelial Cells ◽

Vascular Endothelial ◽

Hmg Coa Reductase ◽

Endothelin 1 ◽

Reductase Inhibitors ◽

The Possible Therapeutic Actions of Peroxisome Proliferator-Activated Receptor α(PPARα) Agonists,PPARγ Agonists,3-Hydroxy-3- Methylglutaryl Coenzyme A (HMG-CoA)Reductase Inhibitors,Angiotensin Converting Enzyme (ACE)Inhibitors and Calcium (Ca)-Antagonists on Vascular Endothelial Cells

Current Drug Targets - Cardiovascular & Hematological Disorders ◽

10.2174/1568006043481329 ◽

2004 ◽

Vol 4 (1) ◽

pp. 35-52 ◽

Cited By ~ 6

Author(s):

Ikuo Inoue ◽

Shigehiro Katayama

Keyword(s):

Endothelial Cells ◽

Angiotensin Converting Enzyme ◽

Peroxisome Proliferator ◽

Vascular Endothelial ◽

Converting Enzyme ◽

Peroxisome Proliferator Activated Receptor ◽

Reductase Inhibitors ◽

HMG-CoA Reductase Inhibitors Suppress Intracellular Calcium Mobilization and Membrane Current Induced by Lysophosphatidylcholine in Endothelial Cells

Circulation ◽

10.1161/hc0802.104457 ◽

2002 ◽

Vol 105 (8) ◽

pp. 962-967 ◽

Cited By ~ 55

Author(s):

Keiko Yokoyama ◽

Toshiyuki Ishibashi ◽

Hiroshi Ohkawara ◽

Junko Kimura ◽

Isao Matsuoka ◽

...

Keyword(s):

Endothelial Cells ◽

Intracellular Calcium ◽

Calcium Mobilization ◽

Membrane Current ◽

Hmg Coa Reductase ◽

Reductase Inhibitors ◽

Intracellular Calcium Mobilization ◽

The influence of HMG-CoA reductase inhibitors on elastolytic activity in cultured human umbilical vein endothelial cells stimulated in vitro with κ-elastin

Atherosclerosis Supplements ◽

10.1016/s1567-5688(01)80235-x ◽

2001 ◽

Vol 2 (2) ◽

pp. 93

Author(s):

W. Wojakowski ◽

J. Gmiński ◽

E. Kotrys-Puchalska ◽

D. Polańska ◽

T. Jurczak

Keyword(s):

Endothelial Cells ◽

Umbilical Vein ◽

Hmg Coa Reductase ◽

Human Umbilical Vein ◽

Reductase Inhibitors ◽

Elastolytic Activity ◽

Umbilical Vein Endothelial Cells ◽

HMG-CoA Reductase Inhibitor Increases GTP Cyclohydrolase I mRNA and Tetrahydrobiopterin in Vascular Endothelial Cells

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/01.atv.0000054659.72231.a1 ◽

2003 ◽

Vol 23 (2) ◽

pp. 176-182 ◽

Cited By ~ 94

Author(s):

Yoshiyuki Hattori ◽

Nobuo Nakanishi ◽

Kazumi Akimoto ◽

Mika Yoshida ◽

Kikuo Kasai

Keyword(s):

Endothelial Cells ◽

Reductase Inhibitor ◽

Vascular Endothelial ◽

Gtp Cyclohydrolase I ◽

Gtp Cyclohydrolase ◽

Hmg Coa Reductase ◽

Hmg Coa Reductase Inhibitor ◽

3-Hydroxy-3-methylglutaryl-CoA Reductase Inhibitors Block Calcium-dependent Tyrosine Kinase Pyk2 Activation by Angiotensin II in Vascular Endothelial Cells

Journal of Biological Chemistry ◽

10.1074/jbc.m009165200 ◽

2001 ◽

Vol 276 (19) ◽

pp. 15761-15767 ◽

Cited By ~ 17

Author(s):

Kumi Satoh ◽

Kazuo Ichihara ◽

Erwin J. Landon ◽

Tadashi Inagami ◽

Hua Tang

Keyword(s):

Endothelial Cells ◽

Angiotensin Ii ◽

Tyrosine Kinase ◽

Vascular Endothelial ◽

Calcium Dependent ◽

Reductase Inhibitors ◽

HMG-CoA Reductase Inhibitors Reduce Adhesion of Human Monocytes to Endothelial Cells

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.2001.6066 ◽

2001 ◽

Vol 289 (4) ◽

pp. 838-844 ◽

Cited By ~ 30

Author(s):

Daniel Teupser ◽

Mathias Bruegel ◽

Olga Stein ◽

Yechezkiel Stein ◽

Joachim Thiery

Keyword(s):

Endothelial Cells ◽

Human Monocytes ◽

Hmg Coa Reductase ◽

Reductase Inhibitors ◽

Enhancement of Migration Activity in Cholesterol-Poor Endothelial Cells by Pretreating with HMG-CoA Reductase Inhibitors

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1994.2331 ◽

1994 ◽

Vol 203 (2) ◽

pp. 1355-1361 ◽

Cited By ~ 10

Author(s):

L.J. Ma ◽

I. Morita ◽

S. Murota

Keyword(s):

Endothelial Cells ◽

Migration Activity ◽

Hmg Coa Reductase ◽

Reductase Inhibitors ◽

All hydrophobic HMG-CoA reductase inhibitors induce apoptotic death in rat pulmonary vein endothelial cells

Atherosclerosis ◽

10.1016/s0021-9150(03)00301-0 ◽

2003 ◽

Vol 170 (2) ◽

pp. 237-243 ◽

Cited By ~ 76

Author(s):

Shigeru Kaneta ◽

Kumi Satoh ◽

Seiichiro Kano ◽

Makoto Kanda ◽

Kazuo Ichihara

Keyword(s):

Endothelial Cells ◽

Pulmonary Vein ◽

Hmg Coa Reductase ◽

Reductase Inhibitors ◽

Apoptotic Death ◽

HMG-CoA Reductase Inhibitors Reduce Nicotine-Induced Expression of Cellular Adhesion Molecules in Cultured Human Coronary Endothelial Cells

Journal of Vascular Research ◽

10.1159/000106464 ◽

2007 ◽

Vol 44 (6) ◽

pp. 460-470 ◽

Cited By ~ 17

Author(s):

Plinio Cirillo ◽

Mario Pacileo ◽

Salvatore De Rosa ◽

Paolo Calabrò ◽

Annarita Gargiulo ◽

...

Keyword(s):

Endothelial Cells ◽

Adhesion Molecules ◽

Cellular Adhesion ◽

Induced Expression ◽

Hmg Coa Reductase ◽

Cellular Adhesion Molecules ◽

Reductase Inhibitors ◽

Coronary Endothelial Cells ◽