3.P.216 Effects of HMG-CoA reductase inhibitors (atorvastatin and simvastatin) on the vasoactive pathways mediated by endothelin-1 and nitric oxide in vascular endothelial cells

Vascular Endothelial ◽

Hmg Coa Reductase ◽

Endothelin 1 ◽

Reductase Inhibitors ◽

The anti-apoptotic effects of HMG-CoA reductase inhibitors on vascular endothelial cells is mediated by ASK1 suppression

Journal of Molecular and Cellular Cardiology ◽

10.1016/j.yjmcc.2007.07.028 ◽

2008 ◽

Vol 44 (2) ◽

pp. 443

Author(s):

Keiichiro Kataoka ◽

Shokei Kim-Mitsuyama

Keyword(s):

Endothelial Cells ◽

Vascular Endothelial ◽

Hmg Coa Reductase ◽

Reductase Inhibitors ◽

Coa Reductase ◽

Apoptotic Effects

The Possible Therapeutic Actions of Peroxisome Proliferator-Activated Receptor α(PPARα) Agonists,PPARγ Agonists,3-Hydroxy-3- Methylglutaryl Coenzyme A (HMG-CoA)Reductase Inhibitors,Angiotensin Converting Enzyme (ACE)Inhibitors and Calcium (Ca)-Antagonists on Vascular Endothelial Cells

Current Drug Targets - Cardiovascular & Hematological Disorders ◽

10.2174/1568006043481329 ◽

2004 ◽

Vol 4 (1) ◽

pp. 35-52 ◽

Cited By ~ 6

Author(s):

Ikuo Inoue ◽

Shigehiro Katayama

Keyword(s):

Endothelial Cells ◽

Angiotensin Converting Enzyme ◽

Peroxisome Proliferator ◽

Vascular Endothelial ◽

Converting Enzyme ◽

Peroxisome Proliferator Activated Receptor ◽

Reductase Inhibitors ◽

Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells.

Journal of Clinical Investigation ◽

10.1172/jci1500 ◽

1998 ◽

Vol 101 (12) ◽

pp. 2711-2719 ◽

Cited By ~ 522

Author(s):

O Hernández-Perera ◽

D Pérez-Sala ◽

J Navarro-Antolín ◽

R Sánchez-Pascuala ◽

G Hernández ◽

...

Keyword(s):

Nitric Oxide ◽

Endothelial Cells ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Vascular Endothelial ◽

Reductase Inhibitors ◽

Coa Reductase ◽

Oxide Synthase ◽

Endothelial Nitric Oxide

The Novel HMG-CoA Reductase Inhibitor, Pitavastatin, Induces a Protective Action in Vascular Endothelial Cells through the Production of Nitric Oxide (NO)

YAKUGAKU ZASSHI ◽

10.1248/yakushi.124.121 ◽

2004 ◽

Vol 124 (3) ◽

pp. 121-126 ◽

Cited By ~ 10

Author(s):

Takashi TOKORO ◽

Juyong WANG ◽

Isao KITAJIMA

Keyword(s):

Nitric Oxide ◽

Endothelial Cells ◽

Reductase Inhibitor ◽

Protective Action ◽

Vascular Endothelial ◽

The Novel ◽

Hmg Coa Reductase ◽

Hmg Coa Reductase Inhibitor ◽

HMG-CoA Reductase Inhibitors Suppress Intracellular Calcium Mobilization and Membrane Current Induced by Lysophosphatidylcholine in Endothelial Cells

Circulation ◽

10.1161/hc0802.104457 ◽

2002 ◽

Vol 105 (8) ◽

pp. 962-967 ◽

Cited By ~ 55

Author(s):

Keiko Yokoyama ◽

Toshiyuki Ishibashi ◽

Hiroshi Ohkawara ◽

Junko Kimura ◽

Isao Matsuoka ◽

...

Keyword(s):

Endothelial Cells ◽

Intracellular Calcium ◽

Calcium Mobilization ◽

Membrane Current ◽

Hmg Coa Reductase ◽

Reductase Inhibitors ◽

Intracellular Calcium Mobilization ◽

The influence of HMG-CoA reductase inhibitors on elastolytic activity in cultured human umbilical vein endothelial cells stimulated in vitro with κ-elastin

Atherosclerosis Supplements ◽

10.1016/s1567-5688(01)80235-x ◽

2001 ◽

Vol 2 (2) ◽

pp. 93

Author(s):

W. Wojakowski ◽

J. Gmiński ◽

E. Kotrys-Puchalska ◽

D. Polańska ◽

T. Jurczak

Keyword(s):

Endothelial Cells ◽

Umbilical Vein ◽

Hmg Coa Reductase ◽

Human Umbilical Vein ◽

Reductase Inhibitors ◽

Elastolytic Activity ◽

Umbilical Vein Endothelial Cells ◽

Cryptotanshinone inhibits endothelin-1 expression and stimulates nitric oxide production in human vascular endothelial cells

Biochimica et Biophysica Acta (BBA) - General Subjects ◽

10.1016/j.bbagen.2005.09.009 ◽

2006 ◽

Vol 1760 (1) ◽

pp. 1-9 ◽

Cited By ~ 35

Author(s):

Zhe Zhou ◽

Sheng-Qi Wang ◽

Yong Liu ◽

Ai-Dong Miao

Keyword(s):

Nitric Oxide ◽

Endothelial Cells ◽

Nitric Oxide Production ◽

Vascular Endothelial ◽

Endothelin 1 ◽

Oxide Production

HMG-CoA Reductase Inhibitor Increases GTP Cyclohydrolase I mRNA and Tetrahydrobiopterin in Vascular Endothelial Cells

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/01.atv.0000054659.72231.a1 ◽

2003 ◽

Vol 23 (2) ◽

pp. 176-182 ◽

Cited By ~ 94

Author(s):

Yoshiyuki Hattori ◽

Nobuo Nakanishi ◽

Kazumi Akimoto ◽

Mika Yoshida ◽

Kikuo Kasai

Keyword(s):

Endothelial Cells ◽

Reductase Inhibitor ◽

Vascular Endothelial ◽

Gtp Cyclohydrolase I ◽

Gtp Cyclohydrolase ◽

Hmg Coa Reductase ◽

Hmg Coa Reductase Inhibitor ◽

3-Hydroxy-3-methylglutaryl-CoA Reductase Inhibitors Block Calcium-dependent Tyrosine Kinase Pyk2 Activation by Angiotensin II in Vascular Endothelial Cells

Journal of Biological Chemistry ◽

10.1074/jbc.m009165200 ◽

2001 ◽

Vol 276 (19) ◽

pp. 15761-15767 ◽

Cited By ~ 17

Author(s):

Kumi Satoh ◽

Kazuo Ichihara ◽

Erwin J. Landon ◽

Tadashi Inagami ◽

Hua Tang

Keyword(s):

Endothelial Cells ◽

Angiotensin Ii ◽

Tyrosine Kinase ◽

Vascular Endothelial ◽

Calcium Dependent ◽

Reductase Inhibitors ◽

Influence of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitors on endothelial nitric oxide synthase and the formation of oxidants in the vasculature

Atherosclerosis ◽

10.1016/s0021-9150(03)00100-x ◽

2003 ◽

Vol 169 (1) ◽

pp. 19-29 ◽

Cited By ~ 38

Author(s):

R Parker

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Hmg Coa Reductase ◽

Reductase Inhibitors ◽

Coa Reductase ◽

Oxide Synthase ◽

Endothelial Nitric Oxide