Protective Effects of Hydrogen-Rich Saline Against Erectile Dysfunction in a Streptozotocin Induced Diabetic Rat Model

2014 ◽  
Vol 2014 ◽  
pp. 118-119
Author(s):  
A.W. Shindel
Keyword(s):  
Erectile Dysfunction ◽  
Rat Model ◽  
Diabetic Rat ◽  
Protective Effects ◽  
Diabetic Rat Model

Protective Effects of Hydrogen-Rich Saline Against Erectile Dysfunction in a Streptozotocin Induced Diabetic Rat Model

2013 ◽  
Vol 190 (1) ◽  
pp. 350-356 ◽  
Author(s):  
Min Fan ◽  
Xianlin Xu ◽  
Xiaozhou He ◽  
Lujun Chen ◽  
Liren Qian ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Rat Model ◽  
Diabetic Rat ◽  
Protective Effects ◽  
Diabetic Rat Model

scholarly journals MP70-08 TRIMETAZIDINE HAS PROTECTIVE EFFECTS ON SPERMATOGENESIS IN A STREPTOZOTOCIN INDUCED DIABETIC RAT MODEL

2016 ◽  
Vol 195 (4S) ◽  
Author(s):  
Muhammet F. Ozcan ◽  
Emine Hekimoglu ◽  
Kemal Ener ◽  
Mehmet Namuslu ◽  
Ramazan Altintas ◽  
...  
Keyword(s):  
Rat Model ◽  
Diabetic Rat ◽  
Protective Effects ◽  
Diabetic Rat Model

Trimetazidine has protective effects on spermatogenesis in a streptozotocin-induced diabetic rat model

Andrologia ◽  
2017 ◽  
Vol 49 (10) ◽  
pp. e12780
Author(s):  
M. F. Ozcan ◽  
E. R. Hekimoglu ◽  
K. Ener ◽  
M. Namuslu ◽  
R. Altintas ◽  
...  
Keyword(s):  
Rat Model ◽  
Diabetic Rat ◽  
Protective Effects ◽  
Diabetic Rat Model

Beneficial effect of PEDF-transfected ADSCs on erectile dysfunction in a streptozotocin-diabetic rat model

2016 ◽  
Vol 366 (3) ◽  
pp. 623-637 ◽  
Author(s):  
Jun Lu ◽  
Zhixiang Xin ◽  
Qi Zhang ◽  
Di Cui ◽  
Yinglong Xiao ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Beneficial Effect ◽  
Rat Model ◽  
Diabetic Rat ◽  
Diabetic Rat Model ◽  
Streptozotocin Diabetic Rat

scholarly journals Protective effects of umbilical cord mesenchymal stem cell exosomes in a diabetic rat model through live retinal imaging

2021 ◽  
Vol 14 (12) ◽  
pp. 1828-1833
Author(s):  
Yan Fu ◽  
◽  
Guang-Hui He ◽  
Song Chen ◽  
Zhao-Hui Gu ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Protective Effect ◽  
Umbilical Cord ◽  
Rat Model ◽  
Diabetic Rat ◽  
Human Umbilical Cord ◽  
Protective Effects ◽  
Retinal Structure ◽  
Diabetic Rat Model

AIM: To assess the protective effect of human umbilical cord mesenchymal stem cell exosomes (hucMSC-Exs) in a diabetic rat model by using a variety of retinal bioassays. METHODS: hucMSCs were subjected to differential ultracentrifugation for the collection of exosomes, and transmission electron microscopy (TEM), nanoparticle tracking analysis (NTA) using a NanoSight analysis system and Western blotting (WB) were used to analyze the expression of surface marker proteins such as CD63, CD9 and Calnexin. Streptozotocin (STZ) was injected into the intraperitoneal cavity to establish a diabetic model. Rats were divided into a normal group, diabetic group and hucMSC-Ex group. Fundus fluorescein angiography (FFA), optical coherence tomography (OCT) and other live imaging methods were used to observe the fundus of the rats. Finally, the eyeballs of rats from each group were collected for hematoxylin-eosin (HE) staining to further analyze the retinal structure. RESULTS: Through TEM, NTA and WB, we successfully isolated hucMSC-Exs. Subsequent FFA and OCT confirmed that hucMSC-Exs effectively prevented early retinal vascular damage and thickening of the retina. Finally, HE staining of rat retinal sections revealed that exosomes effectively alleviated retinal structure disruption caused by diabetes. CONCLUSION: hucMSC-Exs have a protective effect on the retina in diabetic rat through FFA, OCT and HE staining.

Protective Effects of Hydrogen Saline on Diabetic Retinopathy in a Streptozotocin-Induced Diabetic Rat Model

2012 ◽  
Vol 28 (1) ◽  
pp. 76-82 ◽  
Author(s):  
Xiang Xiao ◽  
Jiping Cai ◽  
Jiajun Xu ◽  
Ruobing Wang ◽  
Jianmei Cai ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Rat Model ◽  
Diabetic Rat ◽  
Protective Effects ◽  
Diabetic Rat Model
Sign in / Sign up

Export Citation Format

Share Document