Case report of infliximab treatment in ulcerative colitis

2002 ◽  
Vol 97 (9) ◽  
pp. S267-S268
Author(s):  
D SMILEY
2020 ◽  
Vol 8 ◽  
pp. 2050313X2096411
Author(s):  
Maria Mikail ◽  
Aze Wilson

Pyoderma gangrenosum is an uncommon neutrophilic dermatosis that is highly associated with pathergy in the setting of trauma or surgery, systemic disease, or may be idiopathic. Herein, we present the case of a 68-year-old female with ulcerative colitis who underwent a subtotal colectomy with an end-ileostomy and presented post-operatively with large, multifocal pyoderma gangrenosum at two abdominal sites. She was managed with intralesional triamcinolone injections and high-dose systemic steroids and was transitioned to IV infliximab. Our case report illustrates the role of infliximab in the treatment of complicated multifocal pyoderma gangrenosum and contemplates the impact of systemic infliximab exposure.


2021 ◽  
Vol 8 (1) ◽  
pp. e000587
Author(s):  
Giacomo Caio ◽  
Lisa Lungaro ◽  
Fabio Caputo ◽  
Maria Muccinelli ◽  
Maria Caterina Marcello ◽  
...  

Inflammatory bowel diseases such as ulcerative colitis (UC) may be complicated by several extraintestinal manifestations. These involve joints, skin, eyes and less commonly lungs and heart. Myocarditis may result from the toxic effect of drugs (ie, mesalazine) commonly used for the treatment of UC or due to infections (eg, Coxsackieviruses, enteroviruses, adenovirus). Here, we report a case of a 26-year old man affected by UC and complicated by two episodes of myocarditis. Both episodes occurred during two severe exacerbations of UC. However, in both cases the aetiology of myocarditis remains uncertain being ascribable to extraintestinal manifestation, drug toxicity or both.


2020 ◽  
Vol 33 (6) ◽  
Author(s):  
Yang Wang ◽  
Yuanyuan Xiao ◽  
Yunzhu Li ◽  
Libing Fu ◽  
Feihong Yu ◽  
...  

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Maria Giuseppina Petruzzelli ◽  
Lucia Margari ◽  
Sara Ivagnes ◽  
Roberto Palumbi ◽  
Francesco Margari

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