The etiology and malignant degeneration of leukoplakia of the cervical mucosa

1935 ◽  
Vol 30 (2) ◽  
pp. 303
Author(s):  
J.P. Greenhill
Keyword(s):  
Malignant Degeneration ◽  
Cervical Mucosa

Malignant degeneration of lichen planus

1971 ◽  
Vol 104 (3) ◽  
pp. 304-307 ◽  
Author(s):  
K. Kronenberg
Keyword(s):  
Lichen Planus ◽  
Malignant Degeneration

Colorectal adenomas and malignant degeneration: Post-polipectomy follow up

1995 ◽  
Vol 108 (4) ◽  
pp. A514
Author(s):  
F. Negrini ◽  
U. Bonassi ◽  
F. Svanoni ◽  
A. Malesci ◽  
R. Colombi ◽  
...  
Keyword(s):  
Colorectal Adenomas ◽  
Malignant Degeneration

L'aumento del segnale di colina coincide con la trasformazione maligna dei gliomi cerebrali: Studio longitidinale con imaging di spettroscopia protonica in risonanza magnetica

1997 ◽  
Vol 10 (2_suppl) ◽  
pp. 18-19
Author(s):  
G. Tedeschi ◽  
N. Lundbom ◽  
R. Raman ◽  
S. Bonavita ◽  
J.H. Duyn ◽  
...  
Keyword(s):  
Proton Magnetic Resonance ◽  
Statistical Significance ◽  
Risonanza Magnetica ◽  
Emission Tomography ◽  
Magnetic Resonance Spectroscopic Imaging ◽  
Malignant Degeneration ◽  
High Grade ◽  
Positron Emission ◽  
Cerebral Gliomas ◽  
High Degree

We tested the hypothesis that proton magnetic resonance spectroscopic imaging (1H-MRSI) can be used as a supportive diagnostic tool to differentiate clinically stable brain tumors from those progressing as a result of either low-to-high grade malignant transformation or of post-therapeutic recurrence. Twenty-seven patients with histologically verified cerebral gliomas were studied repeatedly with 1H-MRSI over a period of 3.5 years. At the time of each 1H-MRSI study, clinical examination, MRI, positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG), and biopsy findings (when available) were used to categorize each patient as being either «stable» or «progressive». Measures of the between-studies percent changes in the choline 1H-MRSI signal intensity, obtained without knowledge of the clinical categorization, segregated the groups with a high degree of statistical significance. All progressive cases showed a between-studies choline signal increase of more than 45%, while all stable cases showed an elevation of less than 35%, no change, or even a decreased signal. We conclude that increased choline coincides with malignant degeneration of cerebral gliomas, and therefore, may possibly be used as a supportive indicator of malignant degeneration of these neoplasms.

On the Presence of a Ciliated Columnar Epithelial Cell Type within the Bovine Cervical Mucosa

1973 ◽  
Vol 36 (5) ◽  
pp. 936-940 ◽  
Author(s):  
R. J. Wordinger ◽  
J. B. Ramsey ◽  
J. F. Dickey ◽  
J. R. Hill
Keyword(s):  
Epithelial Cell ◽  
Cell Type ◽  
Epithelial Cell Type ◽  
Columnar Epithelial Cell ◽  
Cervical Mucosa

scholarly journals Porokeratosis with an Invasive Squamous Cell Carcinoma: A Case Report and Review of Literature

2014 ◽  
Vol 32 (1) ◽  
pp. 31-36
Author(s):  
M Nessa ◽  
L Khondker ◽  
MA Bari ◽  
MSI Khan ◽  
M Rahman ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Granular Layer ◽  
Malignant Degeneration ◽  
Invasive Squamous Cell Carcinoma ◽  
Review Of Literature ◽  
Large Plaque ◽  
Cornoid Lamella ◽  
Multiple Nodules

Porokeratosis is a clonal disorder of epidermal keratinization, which is characterized by hyperkeratotic papules or plaques that are surrounded by a thread-like elevated border. The histopathologic hallmark of porokeratosis is the cornoid lamella, which is a thin column of parakeratosis that overlies a thin or absent granular layer and that corresponds to the raised, hyperkeratotic border. Porokeratosis has five clinical types and malignant degeneration has been described in all forms of porokeratosis. We report a forty five year old farmer with a large plaque in chest for 30 years and multiple nodules within the large plaque for 2 years. A section of skin from margin of the plaque reveals histopathological features of porokeratosis and section from nodules reveals an invasive squamous cell carcinoma. To the best of our knowledge, this is the first reported case of porokeratosis transformed to squamous cell carcinoma on Bangladesh. DOI: http://dx.doi.org/10.3329/jbcps.v32i1.21035 J Bangladesh Coll Phys Surg 2014; 32: 31-36

scholarly journals Dark Proteome Database: Studies on Dark Proteins

2019 ◽  
Author(s):  
Nelson Perdigão
Keyword(s):  
Natural Killer Cells ◽  
Homology Modeling ◽  
3D Structure ◽  
Model Organisms ◽  
Human Organism ◽  
Experimental Characterization ◽  
Proteome Database ◽  
Protein Universe ◽  
Cervical Mucosa ◽  
Higher Eukaryotes

The dark proteome as we define it, is the part of the proteome where 3D structure has not been observed either by homology modeling or by experimental characterization in the protein universe. From the 550.116 proteins available in Swiss-Prot (as of July 2016) 43.2% of the Eukarya universe and 49.2% of the Virus universe are part of the dark proteome. In Bacteria and Archaea, the percentage of the dark proteome presence is significantly less, with 12.6% and 13.3% respectively. In this work, we present the map of the dark proteome in Human and in other model organisms. The most significant result is that around 40%- 50% of the proteome of these organisms are still in the dark, where the higher percentages belong to higher eukaryotes (mouse and human organisms). Due to the amount of darkness present in the human organism being more than 50%, deeper studies were made, including the identification of ‘dark’ genes that are responsible for the production of the so-called dark proteins, as well as, the identification of the ‘dark’ organs where dark proteins are over represented, namely heart, cervical mucosa and natural killer cells. This is a step forward in the direction of the human dark proteome.

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