Acute atherosis in preeclampsia: Maternal determinants and fetal outcome in the presence of the lesion

One of the major targets of antiphospholipid antibodies (aPL) is the placenta, the evolution of which during pregnancy has been well documented. Histopathological findings are related to gestational age, and several physiologic and pathologic alterations that occur during its development. The major findings in placentae from aPL positive patients are thrombosis, acute atherosis, a decreased number of syncytio-vascular membranes, increased number of syncytial knots and obliterative arteriopathy. These findings are not specific to the antiphospholipid syndrome (APS) and sometimes do not correlate with the fetal outcome. Histopathological study of placentae may elucidate mechanisms of action of aPL in fetal loss and other obstetric complications. In addition, it may assist in the investigation of the differential diagnosis between APS and pregnancy-induced hypertension. Immunohistochemical studies of local placental proteins contribute to this differential diagnosis.

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Maternal determinants and fetal outcome of multifetal pregnancies in Ahmadu Bello University Teaching Hospital, Zaria, Nigeria

Tropical Journal of Obstetrics and Gynaecology ◽

10.4103/tjog.tjog_75_18 ◽

2019 ◽

Vol 36 (1) ◽

pp. 89

Author(s):

SM Adelaiye ◽

H Adelaiye ◽

PI Onwuhafua

Keyword(s):

Teaching Hospital ◽

Fetal Outcome ◽

University Teaching ◽

Maternal Determinants

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Celiac Disease and Risk of Adverse Fetal Outcome: A Population-Based Cohort Study

Yearbook of Medicine ◽

10.1016/s0084-3873(08)70563-7 ◽

2006 ◽

Vol 2006 ◽

pp. 400-401 ◽

Cited By ~ 1

Author(s):

J.S. Barkin

Keyword(s):

Cohort Study ◽

Celiac Disease ◽

Population Based ◽

Fetal Outcome ◽

Adverse Fetal Outcome

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Fetal outcome of vaginally delivered breech presentation infants born preterm as good as breech presentation infants born by Caesarean section?

Zeitschrift für Geburtshilfe und Neonatologie ◽

10.1055/s-0031-1293469 ◽

2011 ◽

Vol 215 (S 01) ◽

Author(s):

M Vidovics ◽

B Maier ◽

VR Jacobs ◽

T Fischer

Keyword(s):

Caesarean Section ◽

Breech Presentation ◽

Fetal Outcome

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Relative Sensitivity of Different Tests in the Detection of Low Titer Lupus Anticoagulants

Thrombosis and Haemostasis ◽

10.1055/s-0038-1647032 ◽

1988 ◽

Vol 60 (02) ◽

pp. 217-219 ◽

Cited By ~ 26

Author(s):

B Lesperance ◽

M David ◽

J Rauch ◽

C Infante-Rivard ◽

G E Rivard

Keyword(s):

Relative Sensitivity ◽

Fetal Outcome ◽

Anticardiolipin Antibodies ◽

Lupus Anticoagulants ◽

Normal Plasma ◽

Coagulation Tests ◽

High Dilutions ◽

Tissue Thromboplastin ◽

High Concentrations ◽

Kaolin Clotting Time

SummaryLupus anticoagulants (LA) and anticardiolipin antibodies have been strongly associated with recurrent abortion and fetal death. Because steroids have been reported to improve the fetal outcome of LA associated pregnancies, presumably by decreasing the levels of LA, it becomes desirable to have a simple and reliable test to monitor the levels of the putative antibody. To this effect, we assessed the capacity of the following coagulation tests to detect the presence of LA in serial dilutions of patient plasma with pooled normal plasma: kaolin clotting time (KCT), tissue thromboplastin inhibition test (TTIT), dilute Russell Viper venom time (DRVVT) and activated partial thromboplastin time with standard and high concentrations of phospholipids (SC and HCAPTT). All samples were also evaluated for the presence of anticardiolipin antibodies with an ELISA. The KCT was able to detect LA at a much greater dilution in normal plasma than any of the other clotting assays. The ELISA was comparable to KCT in its ability to detect high dilutions of LA.

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Schwere Präeklampsie mit fetaler Zentralisation in der 24. SSW- geburtshilfliches Managment und fetal outcome

Geburtshilfe und Frauenheilkunde ◽

10.1055/s-2006-952452 ◽

2006 ◽

Vol 66 (S 01) ◽

Author(s):

B Hinken ◽

K Bartz ◽

D Grabow ◽

AC Lehmann ◽

G Schwesinger

Keyword(s):

Fetal Outcome

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TO REVIEW THE TIMING OF INTERVENTION WHICH WILL PROVIDE THE BEST OUTCOME IN HYPOTHYROIDISM IN PREGNANCY

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v3i4.209 ◽

2019 ◽

Vol 3 (4) ◽

Author(s):

Dr. Archana Mohana ◽

Dr. Sujata Badoniya

Keyword(s):

Pregnant Women ◽

Thyroid Disease ◽

Fetal Outcome ◽

Thyroxine Therapy ◽

In Pregnancy

The Aim of this study is to Review the timing of intervention which will provide the Best Outcome in Hypothyroidism in Pregnancy. Hypothyroid pregnant women are appropriately managed with regular antenatal checkup and thyroxine therapy during pregnancy, a good maternal and fetal outcome can be achieved and congenital cretinism and other neuro developmental sequele in the offspring can be averted. Keywords: Intervention, Hyperthyroidism, Pregnancy & Thyroid disease.

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