P-090: The autonomic disorders and high blood pressure during Guillain Barre syndrome in children crossed University Hospital Center in Oran

2015 ◽  
Vol 64 ◽  
pp. S54
Author(s):  
D. Batouche ◽  
K. Elhalimi ◽  
N. Chaib ◽  
S. Abassini ◽  
Y. Touhami ◽  
...  
2019 ◽  
Vol 12 (4) ◽  
pp. e226925 ◽  
Author(s):  
Preet Mukesh Shah ◽  
Vijay Waman Dhakre ◽  
Ramya Veerasuri ◽  
Anand Bhabhor

A 56-year-old woman with a medical history of hypertension presented to our hospital with back pain, abdominal pain, vomiting and elevated blood pressure. The laboratory parameters including evaluation for secondary hypertension were within normal ranges at the time of presentation. During her hospitalisation, fluctuations in her blood pressure and pulse were observed which were attributed to autonomic disturbances, the cause of which was unknown. On the seventh day after presentation to the hospital, the patient developed focal seizures and slurred speech which was believed to be secondary to hyponatraemia detected at that time. Hyponatraemia improved with hypertonic saline and she experienced no further seizures. On the eighth day of her admission, she developed acute flaccid paralysis of all her limbs and respiratory distress. We concluded this to be secondary to Guillain-Barre syndrome (GBS). She responded to plasmapheresis.The presence of dysautonomia and hyponatraemia before the onset of paralysis makes this a rare presentation of GBS.


2021 ◽  
pp. practneurol-2021-003110
Author(s):  
Neha Kumta ◽  
Angus Carter ◽  
Peter Schuller ◽  
Hannah Evans ◽  
Anika Graffunder

A 48-year-old man with severe Guillain-Barré syndrome suffered complete paralysis, and for 31 days could not communicate with the outside world, while remaining fully conscious. After recovery, he provided feedback on aspects of his care, such as mechanical ventilation, physical therapy, and communication. Conventional low tidal volume normocapnic ventilation induced ongoing and profound dyspnoea, occasionally relieved by modest increases in minute ventilation. Routine and apparently benign physical therapy was extremely painful, which was not reflected in heart rate or blood pressure changes. When he eventually re-established communication after many weeks, via slight eye movements, his first message was to express a particular distressing symptom. His case is a valuable reminder of the sometimes large gap between clinical measurements and assumptions and the subjective patient experience. We propose several approaches to address such issues in other paralysed but conscious patients.


1999 ◽  
Vol 96 (6) ◽  
pp. 613 ◽  
Author(s):  
Djillali ANNANE ◽  
Véronique BAUDRIE ◽  
Anne-Sophie BLANC ◽  
Dominique LAUDE ◽  
Jean-Claude RAPHAL ◽  
...  

2016 ◽  
Vol 74 (9) ◽  
pp. 718-722 ◽  
Author(s):  
Hasan Huseyin Ozdemir

ABSTRACT The purpose of this study was to investigate the prognostic value of the pretreatment and post-treatment albumin level, neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR) in subtypes of Guillain-Barré syndrome (GBS). A retrospective analysis of 62 patients with GBS treated between 2011 and 2015 in Dicle University Hospital, Turkey, was carried out. The pretreatment and post-treatment albumin, NLR, and PLR were documented, together with acute inflammatory demyelinating polyradiculoneuropathy (AIDP), acute motor axonal neuropathy, motor sensory axonal neuropathy, and Hughes’ scores. Post-treatment albumin levels in GBS were significantly reduced, and albumin level was negatively correlated with the Hughes scores. Elevated pretreatment NLRs and PLRs were significantly associated with AIDP. There were no correlations between the Hughes scores, NLR, and PLR. The results point to a negative correlation between albumin levels and GBS disability and suggest that the NLR and PLR may be promising blood biomarkers of AIDP.


2015 ◽  
Vol 73 (10) ◽  
pp. 848-851 ◽  
Author(s):  
Daniel Agustin Godoy ◽  
Alejandro Rabinstein

Objective In certain situations, severe forms of Guillain-Barré syndrome (GBS) show no response or continue to deteriorate after intravenous immunoglobulin (IVIg) infusion. It is unclear what the best treatment option would be in these circumstances.Method This is a case report on patients with severe axonal GBS in whom a second cycle of IVIg was used.Results Three patients on mechanical ventilation who presented axonal variants of GBS, with autonomic dysfunction, bulbar impairment and Erasmus score > 6, showed no improvement after IVIg infusion of 400 mg/kg/d for 5 days. After 6 weeks, we started a second cycle of IVIg using the same doses and regimen as in the previous one. On average, 5 days after the second infusion, all the patients were weaned off mechanical ventilation and showed resolution of their blood pressure and heart rate fluctuations.Conclusions A second cycle of IVIg may be an option for treating severe forms of GBS.


2007 ◽  
Vol 135 (1-2) ◽  
pp. 139
Author(s):  
Mana Higashihara ◽  
Masahiro Sonoo ◽  
Satoko Unno ◽  
Hideji Hashida ◽  
Katsuhiko Takeda

1993 ◽  
Vol 43 ◽  
pp. 80
Author(s):  
A. Ginanneschi ◽  
M. Marinoni ◽  
D. Inzitari ◽  
S. Piacentini ◽  
G. Marconi ◽  
...  

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