Short-term variability of blood pressure and heart rate in Guillain-Barré syndrome without respiratory failure

1999 ◽  
Vol 96 (6) ◽  
pp. 613 ◽  
Author(s):  
Djillali ANNANE ◽  
Véronique BAUDRIE ◽  
Anne-Sophie BLANC ◽  
Dominique LAUDE ◽  
Jean-Claude RAPHAL ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Respiratory Failure ◽  
Guillain Barre Syndrome ◽  
Short Term ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Short Term Variability

Short-term variability of blood pressure and heart rate in Guillain-Barreá syndrome without respiratory failure

1999 ◽  
Vol 96 (6) ◽  
pp. 613-621 ◽  
Author(s):  
Djillali ANNANE ◽  
Véronique BAUDRIE ◽  
Anne-Sophie BLANC ◽  
Dominique LAUDE ◽  
Jean-Claude RAPHAËL ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Respiratory Failure ◽  
Plasma Noradrenaline ◽  
Heart Period ◽  
Short Term ◽  
Heart Period Variability ◽  
Period Variability ◽  
Head Up Tilt ◽  
Short Term Variability

The effect of Guillain-Barré syndrome (GBS) on the short-term variability of blood pressure and heart rate was evaluated in six patients presenting with a moderate form of the syndrome, i.e. unable to stand up unaided and without respiratory failure, at the height of the disease and during recovery. The patients were compared with six age-matched healthy volunteers. During the acute phase of the syndrome, GBS patients exhibited a significant heart rate elevation (+26 beats/min compared with healthy subjects), but the acceleratory response to atropine, or to 60 ° head-up tilt, was maintained. Resting plasma noradrenaline levels were high in acute GBS, but the secretory response to tilt was preserved. Desensitization to noradrenaline was observed in acute GBS with a reduced pressor action of this α-adrenoceptor agonist. Blood pressure levels were normal and head-up tilt did not induce orthostatic hypotension in this moderate form of GBS. Power spectral analysis demonstrated marked alterations in cardiovascular variability. The overall heart period variability was markedly reduced with the reduction predominantly in the high-frequency (respiratory) range (-73%). The low-frequency component of heart period variability was also reduced (-54%). This cardiovascular profile of moderate GBS at the height of the disease could result from a demyelination of the reflex loop controlling respiratory oscillations in heart rate and from a desensitization of the arterial tree to an elevated plasma noradrenaline. Sympathetic nervous activation may contribute to the high resting heart rate in acute GBS.

scholarly journals Is a second cycle of immunoglobulin justified in axonal forms of Guillain-Barré syndrome?

2015 ◽  
Vol 73 (10) ◽  
pp. 848-851 ◽  
Author(s):  
Daniel Agustin Godoy ◽  
Alejandro Rabinstein
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Mechanical Ventilation ◽  
Case Report ◽  
Intravenous Immunoglobulin ◽  
Treatment Option ◽  
Guillain Barre Syndrome ◽  
Ivig Infusion ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Objective In certain situations, severe forms of Guillain-Barré syndrome (GBS) show no response or continue to deteriorate after intravenous immunoglobulin (IVIg) infusion. It is unclear what the best treatment option would be in these circumstances.Method This is a case report on patients with severe axonal GBS in whom a second cycle of IVIg was used.Results Three patients on mechanical ventilation who presented axonal variants of GBS, with autonomic dysfunction, bulbar impairment and Erasmus score > 6, showed no improvement after IVIg infusion of 400 mg/kg/d for 5 days. After 6 weeks, we started a second cycle of IVIg using the same doses and regimen as in the previous one. On average, 5 days after the second infusion, all the patients were weaned off mechanical ventilation and showed resolution of their blood pressure and heart rate fluctuations.Conclusions A second cycle of IVIg may be an option for treating severe forms of GBS.

scholarly journals The clinical characteristics and short-term prognosis in elderly patients with Guillain–Barré syndrome

Medicine ◽  
2017 ◽  
Vol 96 (1) ◽  
pp. e5848 ◽  
Author(s):  
Bing Zhang ◽  
Xiujuan Wu ◽  
Donghui Shen ◽  
Ting Li ◽  
Chunrong Li ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Clinical Characteristics ◽  
Guillain Barre Syndrome ◽  
Short Term ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Differential Effects of Enalapril and Hydralazine on Short-Term Variability of Blood Pressure and Heart Rate in Rats

1992 ◽  
Vol 19 (6) ◽  
pp. 863-869 ◽  
Author(s):  
Marie-Laure Grichois ◽  
Jocelyne Blanc ◽  
Valerie Deckert ◽  
Jean-Luc Elghozi
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Short Term ◽  
Differential Effects ◽  
Short Term Variability

Changes in short-term variability of blood pressure and heart rate during the development of obesity-associated hypertension in high-fat fed dogs

1999 ◽  
Vol 17 (8) ◽  
pp. 1135-1143 ◽  
Author(s):  
P Verwaerde ◽  
J M. Sénard ◽  
M Galinier ◽  
P Rougé ◽  
P Massabuau ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
High Fat ◽  
Short Term ◽  
Short Term Variability

scholarly journals Risk Factors of Respiratory Failure in Children with Guillain-Barré Syndrome

2012 ◽  
Vol 53 (5) ◽  
pp. 295-299 ◽  
Author(s):  
Mei-Hua Hu ◽  
Chiung-Mei Chen ◽  
Kuang-Lin Lin ◽  
Huei-Shyong Wang ◽  
Shao-Hsuan Hsia ◽  
...  
Keyword(s):  
Risk Factors ◽  
Respiratory Failure ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals Dysautonomia and hyponatraemia as harbingers of Guillain-Barre syndrome

2019 ◽  
Vol 12 (4) ◽  
pp. e226925 ◽  
Author(s):  
Preet Mukesh Shah ◽  
Vijay Waman Dhakre ◽  
Ramya Veerasuri ◽  
Anand Bhabhor
Keyword(s):  
Blood Pressure ◽  
Secondary Hypertension ◽  
Guillain Barre Syndrome ◽  
Rare Presentation ◽  
Normal Ranges ◽  
Guillain Barré Syndrome ◽  
History Of ◽  
Autonomic Disturbances ◽  
Guillain Barré ◽  
Time Of Presentation

A 56-year-old woman with a medical history of hypertension presented to our hospital with back pain, abdominal pain, vomiting and elevated blood pressure. The laboratory parameters including evaluation for secondary hypertension were within normal ranges at the time of presentation. During her hospitalisation, fluctuations in her blood pressure and pulse were observed which were attributed to autonomic disturbances, the cause of which was unknown. On the seventh day after presentation to the hospital, the patient developed focal seizures and slurred speech which was believed to be secondary to hyponatraemia detected at that time. Hyponatraemia improved with hypertonic saline and she experienced no further seizures. On the eighth day of her admission, she developed acute flaccid paralysis of all her limbs and respiratory distress. We concluded this to be secondary to Guillain-Barre syndrome (GBS). She responded to plasmapheresis.The presence of dysautonomia and hyponatraemia before the onset of paralysis makes this a rare presentation of GBS.

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