Mitochondrial uncoupling protein 2 in the central nervous system: neuromodulator and neuroprotector

The Central Nervous System

Faculty Opinions recommendation of Mitochondrial uncoupling protein-2 protects the immature brain from excitotoxic neuronal death.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1014060.192750 ◽

2003 ◽

Author(s):

Daniel Ricquier

Keyword(s):

Neuronal Death ◽

Uncoupling Protein ◽

Uncoupling Protein 2 ◽

Immature Brain ◽

Excitotoxic Neuronal Death

Mitochondrial Uncoupling protein‐2 regulates NLRP3 inflammasome

The FASEB Journal ◽

10.1096/fasebj.26.1_supplement.lb679 ◽

2012 ◽

Vol 26 (S1) ◽

Author(s):

Rajan babu Venugopal ◽

Ruan Rollin Cox ◽

prasanna Tamarappu Parthasarathy ◽

Richard F Lockey ◽

Narasaiah Kolliputi

Keyword(s):

Nlrp3 Inflammasome ◽

Uncoupling Protein ◽

Uncoupling Protein 2 ◽

Mitochondrial uncoupling protein 2 is up-regulated in human head and neck, skin, pancreatic, and prostate tumors

Cancer Biomarkers ◽

10.3233/cbm-130369 ◽

2013 ◽

Vol 13 (5) ◽

pp. 377-383 ◽

Cited By ~ 25

Author(s):

Wenjuan Li ◽

Krystle Nichols ◽

Cherie-Ann Nathan ◽

Yunfeng Zhao

Keyword(s):

Head And Neck ◽

Uncoupling Protein ◽

Human Head ◽

Uncoupling Protein 2 ◽

Prostate Tumors ◽

Deletion of Mitochondrial Uncoupling Protein 2 Exacerbates Mitochondrial Damage in Mice Subjected to Cerebral Ischemia and Reperfusion Injury under both Normo- and Hyperglycemic Conditions

International Journal of Biological Sciences ◽

10.7150/ijbs.48204 ◽

2020 ◽

Vol 16 (15) ◽

pp. 2788-2802

Author(s):

Maotao He ◽

Yanmei Ma ◽

Rui Wang ◽

Jianzhong Zhang ◽

Li Jing ◽

...

Keyword(s):

Cerebral Ischemia ◽

Reperfusion Injury ◽

Uncoupling Protein ◽

Mitochondrial Damage ◽

Uncoupling Protein 2 ◽

Ischemia And Reperfusion ◽

Ischemia And Reperfusion Injury ◽

Cerebral Ischemia And Reperfusion

Mitochondrial Uncoupling Proteins in the Central Nervous System

Antioxidants and Redox Signaling ◽

10.1089/ars.2005.7.1173 ◽

2005 ◽

Vol 7 (9-10) ◽

pp. 1173-1181 ◽

Cited By ~ 60

Author(s):

Jeong Sook Kim-Han ◽

Laura L. Dugan

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Uncoupling Proteins ◽

Mitochondrial Uncoupling Proteins ◽

The Central Nervous System

Glutamine regulates mitochondrial uncoupling protein 2 to promote glutaminolysis in neuroblastoma cells

Biochimica et Biophysica Acta (BBA) - Bioenergetics ◽

10.1016/j.bbabio.2019.03.006 ◽

2019 ◽

Vol 1860 (5) ◽

pp. 391-401 ◽

Cited By ~ 8

Author(s):

Anne Rupprecht ◽

Rudolf Moldzio ◽

Bernadette Mödl ◽

Elena E. Pohl

Keyword(s):

Uncoupling Protein ◽

Neuroblastoma Cells ◽

Uncoupling Protein 2 ◽

Tocopherylquinone d-alpha an oxidized form of vitamin E increases mitochondrial uncoupling protein 2 expression in human umbilical vein endothelial cells in vitro

International Journal of Cardiology ◽

10.1016/j.ijcard.2010.05.029 ◽

2010 ◽

Vol 145 (3) ◽

pp. 562-563

Author(s):

Y.M.C. Cheong ◽

Z.A. Almsherqi ◽

Y. Deng ◽

C.S. McLachlan

Keyword(s):

Endothelial Cells ◽

Vitamin E ◽

Uncoupling Protein ◽

Umbilical Vein ◽

Uncoupling Protein 2 ◽

Human Umbilical Vein ◽

Umbilical Vein Endothelial Cells

Mitochondrial uncoupling protein-2 is not involved in palmitate-induced impairment of glucose-stimulated insulin secretion in INS-1E insulinoma cells and is not needed for the amplification of insulin release

Biochemistry and Biophysics Reports ◽

10.1016/j.bbrep.2015.03.008 ◽

2015 ◽

Vol 1 ◽

pp. 8-15 ◽

Cited By ~ 4

Author(s):

Verena Hirschberg Jensen ◽

Charles Affourtit

Keyword(s):

Insulin Secretion ◽

Insulin Release ◽

Uncoupling Protein ◽

Uncoupling Protein 2 ◽

Glucose Stimulated Insulin Secretion ◽

Insulinoma Cells

Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2

Hepatology ◽

10.1053/jhep.2002.32028 ◽

2002 ◽

Vol 35 (4) ◽

pp. 753-761 ◽

Cited By ~ 61

Author(s):

György Baffy ◽

Chen-Yu Zhang ◽

Jonathan N. Glickman ◽

Bradford B. Lowell

Keyword(s):

Fatty Liver ◽

Uncoupling Protein ◽

Uncoupling Protein 2 ◽

Mitochondrial uncoupling protein 2 regulates the effects of paclitaxel on Stat3 activation and cellular survival in lung cancer cells

Carcinogenesis ◽

10.1093/carcin/bgs253 ◽

2012 ◽

Vol 33 (11) ◽

pp. 2065-2075 ◽

Cited By ~ 25

Author(s):

Wen-Pin Su ◽

Ya-Chin Lo ◽

Jin-Jou Yan ◽

I-Chuang Liao ◽

Pei-Jane Tsai ◽

...

Keyword(s):

Lung Cancer ◽

Cancer Cells ◽

Uncoupling Protein ◽

Lung Cancer Cells ◽

Uncoupling Protein 2 ◽

Cellular Survival ◽