Cognitive impairment in spontaneously hypertensive rats: role of central nicotinic receptors. Part II

1997 ◽  
Vol 771 (1) ◽  
pp. 104-114 ◽  
Author(s):  
Mahanandeeshwar Gattu ◽  
Alvin V Terry ◽  
James R Pauly ◽  
Jerry J Buccafusco
1997 ◽  
Vol 771 (1) ◽  
pp. 89-103 ◽  
Author(s):  
Mahanandeeshwar Gattu ◽  
James R Pauly ◽  
Kenneth L Boss ◽  
James B Summers ◽  
Jerry J Buccafusco

1999 ◽  
Vol 277 (4) ◽  
pp. R1057-R1062 ◽  
Author(s):  
Takahiro Nagayama ◽  
Takayuki Matsumoto ◽  
Makoto Yoshida ◽  
Mizue Suzuki-Kusaba ◽  
Hiroaki Hisa ◽  
...  

We investigated the role of nicotinic and muscarinic receptors in secretion of catecholamines induced by transmural electrical stimulation (ES) from isolated perfused adrenal glands of spontaneously hypertensive rats (SHRs) and normotensive Wistar-Kyoto (WKY) rats. ES (1–10 Hz) produced frequency-dependent increases in epinephrine (Epi) and norepinephrine (NE) output as measured in perfusate. The ES-induced increases in NE output, but not Epi output, were significantly greater in adrenal glands of SHRs than in those of WKY rats. Hexamethonium (10–100 μM) markedly inhibited the ES-induced increases in Epi and NE output from adrenal glands of SHRs and WKY rats. Atropine (0.3–3 μM) inhibited the ES-induced increases in Epi and NE output from adrenal glands of SHRs, but not from those of WKY rats. These results suggest that endogenous acetylcholine-induced secretion of adrenal catecholamines is predominantly mediated by nicotinic receptors in SHRs and WKY rats and that the contribution of muscarinic receptors may be different between these two strains.


1994 ◽  
Vol 113 (3) ◽  
pp. 1022-1028 ◽  
Author(s):  
Eneida G. Silva ◽  
Eugenio Frediani-Neto ◽  
Alice T. Ferreira ◽  
Antonio CM. Paiva ◽  
Therezinha B. Paiva

2002 ◽  
Vol 135 (1) ◽  
pp. 206-216 ◽  
Author(s):  
Regina Gisbert ◽  
Khalid Ziani ◽  
Raquel Miquel ◽  
M Antonia Noguera ◽  
M Dolores Ivorra ◽  
...  

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