Comparison of the novel drug Ensaculin with MK-801 on the reduction of hydroxyl radical production in rat striatum after local application of glutamate

2000 ◽  
Vol 857 (1-2) ◽  
pp. 165-171 ◽  
Author(s):  
Peter Teismann ◽  
Boris Ferger
Keyword(s):  
Hydroxyl Radical ◽  
Local Application ◽  
Rat Striatum ◽  
The Novel ◽  
Mk 801 ◽  
Radical Production ◽  
Novel Drug

Dual contradictory roles of cAMP signaling pathways in hydroxyl radical production in the rat striatum

2012 ◽  
Vol 52 (6) ◽  
pp. 1086-1092 ◽  
Author(s):  
Shuichi Hara ◽  
Masamune Kobayashi ◽  
Fumi Kuriiwa ◽  
Toshiji Mukai ◽  
Hajime Mizukami
Keyword(s):  
Hydroxyl Radical ◽  
Signaling Pathways ◽  
Camp Signaling ◽  
Rat Striatum ◽  
Radical Production

Repeated administration of high dose levodopa enhances hydroxyl radical production in the rat striatum denervated with 6-hydroxydopamine

2000 ◽  
Vol 290 (1) ◽  
pp. 33-36 ◽  
Author(s):  
Yasushi Ishida ◽  
Hiroyuki Hashiguchi ◽  
Kazunari Todaka ◽  
Yuta Ishizuka ◽  
Yoshio Mitsuyama
Keyword(s):  
Hydroxyl Radical ◽  
Repeated Administration ◽  
Rat Striatum ◽  
High Dose ◽  
Radical Production ◽  
6 Hydroxydopamine ◽  
Dose Levodopa

scholarly journals Effect of Hyperoxia after Transient Hypoxia-Ischemia on Hydroxyl Radical Production in Newborn Rat Striatum

1999 ◽  
Vol 45 (4, Part 2 of 2) ◽  
pp. 212A-212A
Author(s):  
Osamu Miyake ◽  
Masahiko Yonetani ◽  
Hajime Nakamura
Keyword(s):  
Hydroxyl Radical ◽  
Rat Striatum ◽  
Newborn Rat ◽  
Radical Production ◽  
Hypoxia Ischemia

Hydroxyl radical production via NADPH oxidase in rat striatum due to carbon monoxide poisoning

Toxicology ◽  
2018 ◽  
Vol 394 ◽  
pp. 63-71 ◽  
Author(s):  
Shuichi Hara ◽  
Masamune Kobayashi ◽  
Fumi Kuriiwa ◽  
Kazuya Ikematsu ◽  
Hajime Mizukami
Keyword(s):  
Carbon Monoxide ◽  
Nadph Oxidase ◽  
Hydroxyl Radical ◽  
Carbon Monoxide Poisoning ◽  
Rat Striatum ◽  
Radical Production

Endogenous released ascorbic acid suppresses ethanol-induced hydroxyl radical production in rat striatum

2002 ◽  
Vol 944 (1-2) ◽  
pp. 90-96 ◽  
Author(s):  
Mei Huang ◽  
Wen Liu ◽  
Qiang Li ◽  
Chun Fu Wu
Keyword(s):  
Ascorbic Acid ◽  
Hydroxyl Radical ◽  
Rat Striatum ◽  
Radical Production

A Review on Fast Dissolving Tablet

2017 ◽  
Vol 8 (03) ◽  
Author(s):  
Sagar T. Malsane ◽  
Smita S. Aher ◽  
R. B. Saudagar
Keyword(s):  
Drug Delivery ◽  
Patient Compliance ◽  
Research Area ◽  
Oral Route ◽  
Dosage Forms ◽  
The Novel ◽  
The Past ◽  
Orally Disintegrating Tablets ◽  
Novel Drug ◽  
Experience Difficulty

Oral route is presently the gold standard in the pharmaceutical industry where it is regarded as the safest, most economical and most convenient method of drug delivery resulting in highest patient compliance. Over the past three decades, orally disintegrating tablets (FDTs) have gained considerable attention due to patient compliance. Usually, elderly people experience difficulty in swallowing the conventional dosage forms like tablets, capsules, solutions and suspensions because of tremors of extremities and dysphagia. In some cases such as motion sickness, sudden episodes of allergic attack or coughing, and an unavailability of water, swallowing conventional tablets may be difficult. One such problem can be solved in the novel drug delivery system by formulating “Fast dissolving tablets” (FDTs) which disintegrates or dissolves rapidly without water within few seconds in the mouth due to the action of superdisintegrant or maximizing pore structure in the formulation. The review describes the various formulation aspects, superdisintegrants employed and technologies developed for FDTs, along with various excipients, evaluation tests, marketed formulation and drugs used in this research area.

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