The level of preconceptional peripheral blood natural killer cells which expected a successful treatment outcome using low-dose intravenous gamma immunoglobulin (IVIg) infusion in patients with recurrent spontaneous abortion

2003 ◽  
Vol 80 ◽  
pp. 288-289
Author(s):  
Kwangmoon Yang ◽  
Chanwoo Park ◽  
Keunjae Yoo ◽  
Inok Song ◽  
Jinyoung Kim ◽  
...  
Immunobiology ◽  
2014 ◽  
Vol 219 (3) ◽  
pp. 167-171 ◽  
Author(s):  
Boris V. Dons’koi ◽  
Viktor P. Chernyshov ◽  
Vera Y. Sirenko ◽  
Galina V. Strelko ◽  
Dariia V. Osypchuk

2003 ◽  
Vol 80 ◽  
pp. 691-697 ◽  
Author(s):  
Vassiliki I Michou ◽  
Panagiotis Kanavaros ◽  
Vassilis Athanassiou ◽  
George B Chronis ◽  
Stelios Stabamas ◽  
...  

2017 ◽  
Vol 1 (2) ◽  
pp. 108-114 ◽  
Author(s):  
Kim D. Lu ◽  
Shlomit Radom-Aizik ◽  
Fadia Haddad ◽  
Frank Zaldivar ◽  
Monica Kraft ◽  
...  

IntroductionThe glucocorticoid receptor (GR) is a key receptor involved in inflammatory responses and is influenced by sex steroids. This study measured GR expression on circulating leukocyte subtypes in males and females.MethodsA total of 23 healthy adults (12 female) participated in this study. GR expression was measured in leukocyte subtypes using flow cytometry. Peripheral blood mononuclear cell (PBMC) gene expression of GR (NR3C1), GR β, TGF-β1 and 2, and glucocorticoid-induced leucine zipper (GILZ) were determined by real-time polymerase chain reaction.ResultsLeukocyte GR was lower in females, particularly in granulocytes, natural killer cells, and peripheral blood mononuclear cells (p≤0.01). GR protein expression was different across leukocyte subtypes, with higher expression in eosinophils compared with granulocytes, T lymphocytes, and natural killer cells (p<0.05). There was higher gene expression of GR β in males (p=0.03).ConclusionsThis is the first study to identify sexual dimorphism in GR expression in healthy adults using flow cytometry. These results may begin to explain the sexual dimorphism seen in many diseases and sex differences in glucocorticoid responsiveness.


HemaSphere ◽  
2019 ◽  
Vol 3 (S1) ◽  
pp. 1062
Author(s):  
M. Barbosa ◽  
V. Molla ◽  
A. Mendroni Junior ◽  
M. Goncalves ◽  
E. Kimura ◽  
...  

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