Gain-of-function mutations of platelet-derived growth factor receptor α gene in gastrointestinal stromal tumors

Growth Factor Receptor ◽

Gain Of Function ◽

Correlation of KIT and platelet-derived growth factor receptor α mutations with gene activation and expression profiles in gastrointestinal stromal tumors

Oncogene ◽

10.1038/sj.onc.1208358 ◽

2004 ◽

Vol 24 (6) ◽

pp. 1066-1074 ◽

Cited By ~ 62

Author(s):

Hyun Ju Kang ◽

Suk Woo Nam ◽

Hyunki Kim ◽

Hwanseok Rhee ◽

Nam-Gyun Kim ◽

...

Keyword(s):

Growth Factor ◽

Expression Profiles ◽

Gene Activation ◽

Growth Factor Receptor ◽

Discovery of Potent, Selective Stem Cell Factor Receptor/Platelet Derived Growth Factor Receptor Alpha (c-KIT/PDGFRα) Dual Inhibitor for the Treatment of Imatinib-Resistant Gastrointestinal Stromal Tumors (GISTs)

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.7b00468 ◽

2017 ◽

Vol 60 (12) ◽

pp. 5099-5119 ◽

Cited By ~ 6

Author(s):

Yanli Lu ◽

Fei Mao ◽

Xiaokang Li ◽

Xinyu Zheng ◽

Manjiong Wang ◽

...

Keyword(s):

Stem Cell ◽

Growth Factor ◽

Stem Cell Factor ◽

Growth Factor Receptor ◽

Dual Inhibitor ◽

Stromal Tumors ◽

Imatinib Resistant ◽

Loss of DOG-1 expression associated with shift from spindled to epithelioid morphology in gastric gastrointestinal stromal tumors with KIT and platelet-derived growth factor receptor α mutations

Annals of Diagnostic Pathology ◽

10.1016/j.anndiagpath.2012.10.005 ◽

2013 ◽

Vol 17 (2) ◽

pp. 187-191 ◽

Cited By ~ 6

Author(s):

Abbas Agaimy ◽

Lai Mun Wang ◽

Matthias Eck ◽

Florian Haller ◽

Runjan Chetty

Keyword(s):

Growth Factor ◽

Growth Factor Receptor ◽

Outcome of Patients with Platelet-Derived Growth Factor Receptor Alpha–Mutated Gastrointestinal Stromal Tumors in the Tyrosine Kinase Inhibitor Era

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-11-3025 ◽

2012 ◽

Vol 18 (16) ◽

pp. 4458-4464 ◽

Cited By ~ 97

Author(s):

Philippe A. Cassier ◽

Elena Fumagalli ◽

Piotr Rutkowski ◽

Patrick Schöffski ◽

Martine Van Glabbeke ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Stromal Tumors ◽

Receptor Alpha ◽

Pediatric KIT–Wild-Type and Platelet-Derived Growth Factor Receptor α–Wild-Type Gastrointestinal Stromal Tumors Share KIT Activation but not Mechanisms of Genetic Progression with Adult Gastrointestinal Stromal Tumors

Cancer Research ◽

10.1158/0008-5472.can-07-1938 ◽

2007 ◽

Vol 67 (19) ◽

pp. 9084-9088 ◽

Cited By ~ 113

Author(s):

Katherine A. Janeway ◽

Bernadette Liegl ◽

Amy Harlow ◽

Claudia Le ◽

Antonio Perez-Atayde ◽

...

Keyword(s):

Growth Factor ◽

Growth Factor Receptor ◽

Wild Type ◽

9p21 locus analysis in high-risk gastrointestinal stromal tumors characterized forc-kit and platelet-derived growth factor receptor α gene alterations

Cancer ◽

10.1002/cncr.21113 ◽

2005 ◽

Vol 104 (1) ◽

pp. 159-169 ◽

Cited By ~ 46

Author(s):

Federica Perrone ◽

Elena Tamborini ◽

Gian Paolo Dagrada ◽

Federica Colombo ◽

Lorena Bonadiman ◽

...

Keyword(s):

Growth Factor ◽

High Risk ◽

Growth Factor Receptor ◽

Stromal Tumors ◽

9P21 Locus ◽

Gene Alterations

Abstract 3005: Comprehensive profile of platelet derived growth factor receptor alpha (PDGFRA) mutations in gastrointestinal stromal tumors

10.1158/1538-7445.am2020-3005 ◽

2020 ◽

Author(s):

Homma Khosroyani ◽

Lillian R. Klug ◽

Ajia Town ◽

Jonas Lategahn ◽

Johanna Falkenhorst ◽

...

Keyword(s):

Growth Factor ◽

Growth Factor Receptor ◽

Stromal Tumors ◽

Receptor Alpha ◽

High-Resolution Melting Amplicon Analysis as a Method to Detect c-kitand Platelet-Derived Growth Factor Receptor α Activating Mutations in Gastrointestinal Stromal Tumors

American Journal of Clinical Pathology ◽

10.1309/7teh56k6wwxennqy ◽

2007 ◽

Vol 128 (2) ◽

pp. 230-238 ◽

Cited By ~ 17

Author(s):

Joseph A. Holden ◽

Carlynn Willmore-Payne ◽

Domenico Coppola ◽

Christopher R. Garrett ◽

Lester J. Layfield

Keyword(s):

Growth Factor ◽

High Resolution ◽

High Resolution Melting ◽

Growth Factor Receptor ◽

Stromal Tumors ◽

Activating Mutations

Activating Oncogenic Mutations in C-Kit and Platelet-Derived Growth Factor Receptor (Pdgfr) Tyrosine Kinase Gene in Saudi Gastrointestinal Stromal Tumors (Gists)

Annals of Oncology ◽

10.1093/annonc/mdt203.119 ◽

2013 ◽

Vol 24 ◽

pp. iv70

Author(s):

Muhammad Faiyaz-Ul-Haque ◽

Asma Tulba ◽

Hala Abalkhai ◽

Mohamed Toulimat ◽

Hussa Husseini ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Growth Factor Receptor ◽

Kinase Gene ◽

Stromal Tumors ◽

Oncogenic Mutations ◽

Tyrosine Kinase Gene

Molecular and Immunohistochemical Study of Platelet Derived Growth Factor Receptor Alpha in KIT Negative Gastrointestinal Stromal Tumors; the First Report from Iran

Middle East Journal of Digestive Diseases ◽

10.15171/mejdd.2016.25 ◽

2016 ◽

Vol 8 (3) ◽

pp. 226-231

Author(s):

Bita Geramizadeh ◽

Zahra Jowkar ◽

Seyed-Javad Mousavi

Keyword(s):

Growth Factor ◽

Immunohistochemical Study ◽

Growth Factor Receptor ◽

First Report ◽

Stromal Tumors ◽

Receptor Alpha ◽