W1352 Nutritional Supplementation With Transforming Growth Factor-Beta (TGF-β) Affects Enterocyte Turnover in Correlation With TGF-β Receptor Expression After Massive Small Bowel Resection in a Rat

2010 ◽  
Vol 138 (5) ◽  
pp. S-705
Author(s):  
Ron Shaoul ◽  
Jorge Mogilner ◽  
Arnold G. Coran ◽  
Elena Chemodanov ◽  
Igor Sukhotnik
Keyword(s):  
Growth Factor ◽  
Small Bowel ◽  
Transforming Growth Factor Beta ◽  
Transforming Growth Factor ◽  
Bowel Resection ◽  
Small Bowel Resection ◽  
Receptor Expression ◽  
Growth Factor Beta ◽  
Β Receptor ◽  
Massive Small Bowel Resection

TGF-β Affects Enterocyte Turnover in Correlation With TGF-β Receptor Expression After Massive Small Bowel Resection

2012 ◽  
Vol 55 (6) ◽  
pp. 721-727 ◽  
Author(s):  
Igor Sukhotnik ◽  
Shani Ben Lulu ◽  
Yulia Pollak ◽  
Jacob Bejar ◽  
Arnold G. Coran ◽  
...  
Keyword(s):  
Small Bowel ◽  
Bowel Resection ◽  
Small Bowel Resection ◽  
Receptor Expression ◽  
Β Receptor ◽  
Massive Small Bowel Resection

Increasing Transforming Growth Factor Beta-1 and its Receptor Expression in Human Myocardium with End-Stage Congestive Heart Failure.

2000 ◽  
Vol 6 (S2) ◽  
pp. 612-613
Author(s):  
S. Ren ◽  
C. Wei
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Growth Factor ◽  
Transforming Growth Factor Beta ◽  
Transforming Growth Factor ◽  
Normal Subjects ◽  
Human Myocardium ◽  
Receptor Expression ◽  
Growth Factor Beta ◽  
End Stage

Transforming growth factor-beta (TGF-β) is a growth-regulating peptide that has been shown to enhance collagen production both in vivo and in vitro. The previous studies demonstrated that TGF-β 1 is present in the normal animal myocardium. However, the expression and localization of TGF-β 1 and TGF-P receptor in human myocardium remain unclear. Therefore, the present study was designed to determine the TGF-β 1 and its receptor in human myocardium in normal subjects and in patients with end-stage congestive heart failure (CHF).Human ventricular tissues were obtained from five normal subjects and five patients with end-stage CHF during cardiac transplantation. TGF-β 1 and TGF-beta type I receptor (TGF-βRI) were determined by immunohistochemical staining (IHCS). The results of IHCS was evaluated by staining density scores (0, no staining; 1, minimal staining; 2, mild staining; 3, moderate staining; and 4, strong staining). The positive staining area (+%) in entire section was also determined.

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