Sa1029 Clostridium difficile Infection Among Patients Who Have Undergone Orthotropic Liver Transplantation

2014 ◽  
Vol 146 (5) ◽  
pp. S-942 ◽  
Author(s):  
Shashank Garg ◽  
Amy Wozniak ◽  
Shmuel Shoham ◽  
James P. Hamilton ◽  
Ahmet Gurakar
Keyword(s):  
Liver Transplantation ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection

scholarly journals 453Association of Clostridium difficile Infection (CDI) with Excess Mortality after Liver Transplantation (LT) for Hilar Cholangiocarcinoma (CCA)

2014 ◽  
Vol 1 (suppl_1) ◽  
pp. S171-S171
Author(s):  
Poornima Ramanan ◽  
Nathan W. Cummins ◽  
Mark P. Wilhelm ◽  
Julie K. Heimbach ◽  
Ross Dierkhising ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Hilar Cholangiocarcinoma ◽  
Excess Mortality

Liver Graft Failure and Hyperbilirubinemia in Liver Transplantation Recipients After Clostridium difficile Infection

2011 ◽  
Vol 43 (10) ◽  
pp. 3819-3823 ◽  
Author(s):  
C. Rochon ◽  
A. Kardashian ◽  
B. Mahadevappa ◽  
G. Gunasekaran ◽  
J. Sharma ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Graft Failure ◽  
Liver Graft

scholarly journals Successful Fecal Microbiota Transplantation in a Patient with Severe Complicated Clostridium difficile Infection after Liver Transplantation

2018 ◽  
Vol 12 (1) ◽  
pp. 76-84 ◽  
Author(s):  
Kai Markus Schneider ◽  
Theresa H. Wirtz ◽  
Daniela Kroy ◽  
Stefanie Albers ◽  
Ulf Peter Neumann ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Disease Burden ◽  
Fecal Microbiota Transplantation ◽  
Solid Organ Transplantation ◽  
Fecal Microbiota ◽  
Solid Organ ◽  
Healthcare Associated

Clostridium difficile infection (CDI) represents one of the most common healthcare-associated infections. Due to increasing numbers of recurrences and therapy failures, CDI has become a major disease burden. Studies have shown that fecal microbiota transplantation (FMT) can both be a safe and highly efficacious therapy for patients with therapy-refractory CDI. However, patients undergoing solid organ transplantation are at high risk for CDI due to long-term immunosuppression, previous antibiotic therapy, and proton pump inhibitor use. Additionally, these patients may be especially prone to adverse events related to FMT. Here, we report a successful FMT in a patient with severe therapy-refractory CDI after liver transplantation.

Repeated Clostridium difficile infection after living donor liver transplantation

2018 ◽  
Vol 11 (4) ◽  
pp. 309-311
Author(s):  
Kyohei Abe ◽  
Hiroaki Shiba ◽  
Kenei Furukawa ◽  
Taro Sakamoto ◽  
Yuichi Ishida ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Donor Liver ◽  
Donor Liver Transplantation

Self-Administered Home Series Fecal “Minitransplants” for Recurrent Clostridium difficile Infection on a Rectal Remnant

2015 ◽  
Vol 24 (4) ◽  
pp. 531-533 ◽  
Author(s):  
Daniel Popa ◽  
Mihaela Laszlo ◽  
Lidia Ciobanu ◽  
Elena Ucenic ◽  
Manuela Mihalache ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Toxic Megacolon ◽  
Fecal Microbiota ◽  
Recurrent Infections ◽  
Resonance Imaging ◽  
Vaginal Infection ◽  
Fecal Microbiota Transplant ◽  
Recurrent Clostridium Difficile Infection

A fecal microbiota transplant has proved to be an extremely effective method for patients with recurrent infections with Clostridium difficile. We present the case of a 65-year-old female patient with multiple Clostridium difficile infection (CDI) relapses on the rectal remnant, post-colectomy for a CDI-related toxic megacolon. The patient also evidenced associated symptomatic Clostridium difficile vaginal infection. She was successfully treated with serial fecal “minitransplants” (self-administered at home) and metronidazole ovules.Abbreviations: GI: gastrointestinal; MRI: magnetic resonance imaging; CDI: Clostridium difficile infection; FMT: fecal microbiota transplant.

Serendipity in Refractory Celiac Disease: Full Recovery of Duodenal Villi and Clinical Symptoms after Fecal Microbiota Transfer

2016 ◽  
Vol 25 (3) ◽  
pp. 385-388 ◽  
Author(s):  
Yvette H. Van Beurden ◽  
Tom Van Gils ◽  
Nienke A. Van Gils ◽  
Zain Kassam ◽  
Chris J.J. Mulder ◽  
...  
Keyword(s):  
Celiac Disease ◽  
T Cell ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Cell Lymphoma ◽  
Fecal Microbiota ◽  
Disease Type ◽  
T Cell Lymphoma ◽  
Type Ii ◽  
Refractory Celiac Disease

Treatment of refractory celiac disease type II (RCD II) and preventing the development of an enteropathy associated T-cell lymphoma in these patients is still difficult. In this case report, we describe a patient with RCD II who received fecal microbiota transfer as treatment for a recurrent Clostridium difficile infection, and remarkably showed a full recovery of duodenal villi and disappearance of celiac symptoms. This case suggests that altering the gut microbiota may hold promise in improving the clinical and histological consequences of celiac disease and/or RCD II. Abbreviations: CDI: Clostridium difficile infection; EATL : enteropathy associated T-cell lymphoma; FMT: fecal microbiota transfer; IEL: intraepithelial lymphocytes; RCD II: refractory celiac disease type II; TPN: total parenteral nutrition.

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