Sa157 CORRELATION OF IMPEDANCE-PH MONITORING AND REFLUX SCINTIGRAPHY RESULTS IN LARYNGOPHARYNGEAL REFLUX DISEASE

2021 ◽  
Vol 160 (6) ◽  
pp. S-442-S-443
Author(s):  
Jin-soo Park ◽  
Hans Van Der Wall ◽  
Gregory L. Falk
2009 ◽  
Vol 123 (S31) ◽  
pp. 42-47 ◽  
Author(s):  
K Sato ◽  
H Umeno ◽  
S Chitose ◽  
T Nakashima

AbstractObjectives:Double-probe, 24-hour pH monitoring remains the ‘gold standard’ for the diagnosis of laryngopharyngeal reflux disease, even though there is no consensus on how to interpret the data collected.Methods:Tetra-probe, 24-hour pH monitoring was performed in 56 patients with suspected laryngopharyngeal reflux, in order to investigate patterns of laryngopharyngeal and gastroesophageal reflux.Results:The number of reflux episodes and the total and percentage time periods spent with pH < 4.0 were correlated with the distance of the probe from the lower oesophageal sphincter. The number of reflux episodes and the total and percentage time periods with pH < 4.0 were greater when patients were upright (i.e. during the daytime). There were few laryngopharyngeal reflux events recorded for pH levels of <4.0; however, there were a significant number of laryngopharyngeal reflux events recorded for pH levels of <5.0, a level capable of causing laryngopharyngeal reflux disease. When a pH level of <5.0 was used, the number, total time and percentage time of laryngopharyngeal reflux episodes was greater during the supine period (i.e. during sleeping) in a quarter of the cases, compared with results when a pH of <4.0 was used.Conclusions:It is valid to use a pH level of 5.0 as indicative of laryngopharyngeal reflux in the hypopharynx.


2021 ◽  
Author(s):  
Gang Wang ◽  
Lei Wang ◽  
Zhezhe Sun ◽  
Yuzhu Guo ◽  
Hongdan Liu ◽  
...  

Abstract ObjectiveTo assess the diagnostic value of W score which was supposed to identify laryngopharyngeal reflux disease (LPRD) patients from the normal population by Dx-pH monitoring, comparing with Ryan score.MethodsOne hundred and eight patients with suspected LPRD and complete follow-up results after more than 8 weeks of anti-reflux therapy were enrolled from the Department of Otolaryngology-Head and Neck Surgery, Gastroenterology and Respiratory Medicine of seven hospitals. Their Dx-pH monitoring data before treatment were reanalyzed to obtain the W score besides Ryan score and then the diagnostic sensitivity and specificity were compared according to the result of anti-reflux therapy.ResultsEighty-seven (80.6%) cases were anti-reflux therapy effective, and 21 patients (19.4%) were ineffective. Twenty-seven patients (25.0%) had a positive Ryan score. The W score was positive in 79 (73.1%) patients. There were 52 patients who had a negative Ryan score, but a positive W score. The diagnostic sensitivity, specificity, positive predictive value and negative predictive value of the Ryan score were 28.7%, 90.5%, 92.6% and 23.5%, respectively (kappa = 0.092, p = 0.068), whereas those of the W score for LPRD were 83.9%, 71.4%, 92.4% and 51.7%, respectively (kappa = 0.484, p < 0.001).ConclusionsW score is much more sensitive for the diagnosis of LPRD. Prospective studies with larger patient populations are necessary to validate and improve the new diagnostic criteria.Trial RegistrationChinese Clinical Trial Registry: ChiCTR1800014931.


e-CliniC ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 457
Author(s):  
Karin I. Rompas ◽  
Steward K. Mengko ◽  
Ora Et Labora I. Palandeng

Abstract: Lifestyle and behavior changes can have bad impacts on our health. One of the diseases that can be caused by lifestyle changes is pharyngeal larynx reflux. Pharyngeal laryngeal reflux is a state of return of the contents of the stomach to the larynx and pharynx causing an inflammatory reaction to the mucous membranes of the larynx and pharynx. In an attempt to diagnose pharyngeal larynx reflux, a follow-up examination is required. In this case there are several examinations that can be done to confirm the diagnosis of pharyngeal larynx reflux. This study was aimed to obtain the diagnostic approaches in laringopharyngeal reflux cases. This was a literature review study using two databases namely PubMed and ClinicalKey. The keywords used were laringophaingeal reflux and laryngopharyngeal reflux disease. After being selected based on inclusion and exclusion criteria, nine literatures using experimental research methods. were obtained. The results showed that several examinations that could be performed in diagnosing laringofaringeal reflux, as follows: anamnesis, physical examination, pH-monitoring, reflux findings score, reflux symptom score, PEP-test, reflux sign assessment, reflux symptom score, immunohistochemistry, and fiber-optic laryngoscopy. In conclusion, supporting examinations are needed to confirm the diagnosis of pharyngeal larynx reflux.Keywords: refluks laring faring; laryngopharyngeal reflux disease. Abstrak: Perubahan gaya hidup dan perilaku dapat berdampak pada kesehatan tubuh. Salah satu penyakit yang dapat diakibatkan oleh perubahan gaya hidup yaitu refluks laring faring. Refluks laring faring merupakan keadaan kembalinya isi lambung ke laring dan faring sehingga menyebabkan reaksi inflamasi pada selaput lendir laring dan faring. Untuk menegakkan diagnosis refluks laring faring dibutuhkan pemeriksaan lanjutan. Penelitian ini bertujuan untuk mengetahui pendekatan diagnosis yang dapat dilakukan dalam pemeriksaan kasus refluks laring faring. Jenis penelitian ialah literature review dengan pencarian data menggunakan dua database yaitu PubMed dan ClinicalKey. Kata kunci yang digunakan yaitu refluks laring faring and laryngopharyngeal reflux disease. Setelah diseleksi berdasarkan kriteria inklusi dan eksklusi, didapatkan sembilan literatur yang menggunakan metode penelitian eksperimental. Hasil peneli-tian mendapatkan pemeriksaan-pemeriksaan yang dilakukan dalam menegakkan diagnosis refluks laring faring ialah: anamnesis, pemeriksaan fisik, pH-monitoring, skor temuan refluks, skor gejala refluks, PEP-test, reflux sign assessment, reflux symptom score, immunohistochemistry, dan fiber-optic laryngoscopy. Simpulan penelitian ini ialah pemeriksaan penunjang perlu dilakukan untuk menegakkan diagnosis refluks laring faring.Kata kunci: refluks laring faring; laryngopharyngeal reflux disease


2019 ◽  
Vol 48 (3) ◽  
pp. 030006051988831 ◽  
Author(s):  
Junbo Zhang ◽  
Shuifang Xiao ◽  
Xiaowan Du ◽  
Xin Zhao ◽  
Junxiao Jia

Objective This study aimed to evaluate knowledge of laryngopharyngeal reflux disease (LPRD) among otolaryngologists in 3A hospitals in Beijing. Methods A cross-sectional questionnaire survey of LPRD knowledge was conducted with otolaryngologists in 40 3A hospitals in Beijing. A response rate of <80% was obtained from one hospital, so data from 331 valid questionnaires from the other 39 hospitals were analysed. Results The most common source of LPRD knowledge was academic lectures (80.1%). The most commonly known risk factors, symptoms, clinical signs and associated diseases were unhealthy eating habits (49.2%), foreign body sensation in the pharynx (71.0%), hyperaemia (42.3%) and pharyngolaryngitis (63.7%), respectively. Only 57.7% of otolaryngologists knew about 24-hour pH monitoring as a gold standard diagnostic test for LPRD. The most commonly known treatment option was medication (93.1%). Most physicians (86.7%) had made a clinical diagnosis of LPRD; however, only 59.9% of them had followed up the treatment outcomes. The most common treatment provided was medication (82.6%). Conclusions Knowledge of LPRD among otolaryngologists in 3A hospitals in Beijing was insufficient. Educational programs are needed to increase the knowledge of LPRD among otolaryngologists.


Author(s):  
Manoj Kumar L. ◽  
Anand K. H. ◽  
Raadhika Shree N.

<p class="abstract"><strong>Background:</strong> Laryngopharyngeal reflux disease is an under diagnosed condition due to unavailability of the diagnostic tool that is dual probe pH monitoring and is on the rise in adult population according to El Serag by 4% every year since 1976.</p><p class="abstract"><strong>Methods:</strong> Adult patients coming to the outpatient department between April 2017 to April 2018 were evaluated using reflux symptom index score (RSI). Score greater than 13 were suggestive of laryngopharyngeal reflux and patients underwent 24 hours ambulatory dual probe pH monitoring. 7 or more reflux events in study period were diagnostic of laryngopharygeal reflux.  </p><p class="abstract"><strong>Results:</strong> 3000 adult patients were screened for RSI and 1756 (58.3%) had scored greater than 13. Among these patients 893 patients had 7 or more reflux events in pH monitoring. We found a prevalence of 29.76% in our study population.</p><p class="abstract"><strong>Conclusions:</strong> Prevalence laryngopharyngeal reflux disease needs to assess periodically at regular intervals to create more awareness of the disease and patient education thus preventing from causing chronic illnesses.</p><p class="abstract"> </p>


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