Epigastric abdominal pain in children: Combined empiric treatment and specific H. pylori screening and treatment decrease cost of evaluation

1998 ◽  
Vol 114 ◽  
pp. A898
Author(s):  
AD Olson ◽  
D Deutsch
Keyword(s):  
Abdominal Pain ◽  
Empiric Treatment ◽  
H Pylori ◽  
Epigastric Abdominal Pain

scholarly journals Are Synbiotics added to the Standard Therapy to eradicate Helicobacter pylori in Children Beneficial? A Randomized Controlled Study

2017 ◽  
Vol 7 (1) ◽  
pp. 17-22 ◽  
Author(s):  
Banu N Şirvan ◽  
Merve K Usta ◽  
Nuray U Kızılkan ◽  
Nafiye Urgancı
Keyword(s):  
Helicobacter Pylori ◽  
Abdominal Pain ◽  
Triple Therapy ◽  
Standard Therapy ◽  
Randomized Controlled Study ◽  
Controlled Study ◽  
Randomized Controlled ◽  
Group I ◽  
Dyspeptic Symptoms ◽  
H Pylori

ABSTRACT Aim We aimed to evaluate the role of the addition of Bifidobacterium lactis-containing synbiotic to the triple therapy in the case of Helicobacter pylori eradication, the dyspeptic symptoms, and reducing the side effects of antibiotics. Materials and methods A total of 104 children aged between 5 and 17 years, who were histopathologically diagnosed with H. pylori were enrolled in this study, of whom 100 were included in the analysis. Patients were randomly classified into two groups. In the first group, 50 patients were administered amoxicillin + clarithromycin + lansoprazole for 14 days and B. lactis-containing synbiotic. In the second group, 50 patients were treated with the standard triple therapy. All patients were given information after completion of therapy. Results H. pylori eradication was achieved in 88% in group I who received standard therapy with additional synbiotic and 72% in group II (p = 0.046). The number of patients in the second group who suffered from abdominal pain between the 3rd and 14th day of the treatment was higher (p < 0.05). The addition of probiotics to the triple therapy significantly reduced the frequency of diarrhea, but no significant difference was detected in the frequency of metallic taste (p = 0.04, p = 0.418 respectively). Conclusion The addition of synbiotic to the triple therapy is effective for eradicating H. pylori infection in children and is usually helpful to reduce or eliminate dyspeptic symptoms like abdominal pain, diarrhea, and vomiting. This study suggest that improved tolerance to the eradication treatment also reduces the treatment failure by adding probiotics and encourages the future study using probiotic supplementation in H. pylori treatment. How to cite this article Şirvan BN, Usta MK, Kızılkan NU, Urgancı N. Are Synbiotics added to the Standard Therapy to eradicate Helicobacter Pylori in Children Beneficial? A Randomized Controlled Study. Euroasian J Hepato-Gastroenterol 2017;7(1):17-22.

PP-7 CHILDHOOD RECURRENT ABDOMINAL PAIN IS ASSOCIATED WITH DUODENAL EOSINOPHILIA REGARDLESS OF H. PYLORI INFECTION

2015 ◽  
Vol 61 (4) ◽  
pp. 522-523 ◽  
Author(s):  
L. Wauters ◽  
P. Harris ◽  
C. Serrano ◽  
A. Villagrán ◽  
I. Duarte ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Recurrent Abdominal Pain ◽  
H Pylori

Severe Epigastric Abdominal Pain

Surgery ◽  
2015 ◽  
pp. 493-499
Author(s):  
Michael D. Sgroi ◽  
Brian R. Smith
Keyword(s):  
Abdominal Pain ◽  
Epigastric Abdominal Pain

scholarly journals Porphyria Cutanea Tarda Associated With Acute Hemorrhagic Pancreatitis

2019 ◽  
Vol 7 ◽  
pp. 232470961985276
Author(s):  
Manasi Singh ◽  
Ashley Duckett ◽  
Marc Heincelman
Keyword(s):  
Abdominal Pain ◽  
Physical Examination ◽  
Community Hospital ◽  
Porphyria Cutanea Tarda ◽  
Acute Onset ◽  
Laboratory Evaluation ◽  
Hemorrhagic Pancreatitis ◽  
Acute Hemorrhagic Pancreatitis ◽  
Epigastric Abdominal Pain ◽  
New Onset

Porphyria cutanea tarda (PCT) is a condition of dysregulated heme synthesis that leads to accumulation of photosensitizing precursors with resultant fragility and blistering of the skin. It can be hereditary or acquired and has been known to be associated with hepatic C virus, alcohol, HIV, and estrogen. In this article, we report an unusual presentation of PCT associated with acute hemorrhagic pancreatitis in a 57-year-old man. He presented initially to a community hospital with acute onset of epigastric abdominal pain and new-onset ascites. Lipase was elevated. Diagnostic paracentesis was grossly bloody. He was then transferred to our institution for concern for acute hemorrhagic pancreatitis. On arrival, physical examination demonstrated vesicles and bullae with erythematous bases, in different stages of healing seen over the dorsal aspects of both hands with scaling, scarring, and hypopigmentation and hyperpigmentation of the skin. Laboratory evaluation and skin biopsy confirmed the diagnosis of PCT. Search for an underlying etiology failed to reveal typical predisposing factors. This report illustrates that acute hemorrhagic pancreatitis may be an underlying etiology for PCT.

ACUTE H. PYLORI INFECTION AS A CAUSE OF ABDOMINAL PAIN IN CHILDREN

1999 ◽  
Vol 29 (4) ◽  
pp. 492
Author(s):  
M A Gilger ◽  
A R Opekun ◽  
S Phillips ◽  
W Karnsakul ◽  
M H Nirken ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
H Pylori

Epigastric Abdominal Pain and Weight Loss in a 17-Year-Old Male

2018 ◽  
Vol 57 (10) ◽  
pp. 1250-1253 ◽  
Author(s):  
Maria Josefina Sanchez ◽  
Benjamin C. Lee
Keyword(s):  
Weight Loss ◽  
Abdominal Pain ◽  
Epigastric Abdominal Pain

scholarly journals Helicobacter pylori associated with breastfeeding, nutritional status and recurrent abdominal pain in healthy Nigerian children

2014 ◽  
Vol 8 (04) ◽  
pp. 448-453 ◽  
Author(s):  
Idowu O Senbanjo ◽  
Kazeem A Oshikoya ◽  
Olisamedua F Njokanma
Keyword(s):  
Helicobacter Pylori ◽  
Abdominal Pain ◽  
Nutritional Status ◽  
Recurrent Abdominal Pain ◽  
University Teaching ◽  
Breastfeeding Duration ◽  
Pediatric Care ◽  
Enzyme Linked Immunosorbent Assay ◽  
Healthy Children ◽  
H Pylori

Introduction: There is limited knowledge about the associations of Helicobacter pylori (H. pylori) infections in developing countries. This study aimed to determine the current prevalence and associations of H. pylori infection with breastfeeding practices, nutritional status, and recurrent abdominal pain (RAP) in a group of apparently healthy children and adolescents in Lagos, Nigeria. Methodology: This was a prospective hospital-based study conducted at the Lagos State University Teaching Hospital that involved 118 children who came to the hospital for routine pediatric care. Seroprevalence status of the children was determined by measuring immunoglobulin G antibodies against H. pylori using enzyme-linked immunosorbent assay (ELISA). Results: Seventy-five (63.6%) children were seropositive for H. pylori. The prevalence of H. pylori infection increased significantly from 40.4% in children less than five years of age to 85.1% at six to ten years of age (χ2 = 20.9, p < 0.001). H. pylori infection was associated with low social class (OR = 3.24; 95% CI = 1.20-8.23, p = 0.016) and with RAP (OR = 3.47; 95% CI = 1.55-7.79, p = 0.002), but no association was observed with exclusive breastfeeding, duration of breastfeeding, and under-nutrition. Conclusions: The prevalence of H. pylori infection is high, particularly among children from low socioeconomic backgrounds in Lagos, Nigeria. It is associated with RAP. The effect of this infection on children’s health requires further studies.

scholarly journals Prevalence and factors associated with Helicobacter Pylori infection among children with sickle cell anemia attending Mulago hospital, in Uganda

2019 ◽  
Author(s):  
IDRIS SWALEH MUBIRU ◽  
Phillip Gita Kasirye ◽  
Heather Hume ◽  
Grace Ndeezi
Keyword(s):  
Helicobacter Pylori ◽  
Abdominal Pain ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Epigastric Pain ◽  
Pneumococcal Vaccination ◽  
Helicobacter Pylori Infection ◽  
Mulago Hospital ◽  
Factors Associated ◽  
H Pylori

Abstract Background Children with sickle cell anemia (SCA) have a high predisposition to a range of infections and gastrointestinal disorders. Studies of children living in low income countries have shown high levels of infection with Helicobacter Pylori (H. Pylori), however, there are no reports in children with sickle cell anemia.Objectives We aimed to describe the prevalence and factors associated with Helicobacter pylori infection among children with sickle cell anemia at Mulago Hospital Sickle Cell Clinic, in Uganda.Methods A cross sectional design was employed to consecutively enroll 369 children with confirmed sickle cell anemia aged 5-18 years, attending the Mulago hospital sickle cell clinic. Assessments included; abdominal pain (current, recurrent, generalized or epigastric), dyspeptic symptoms, other relevant medical and social histories. Blood and stool samples were collected and an antigen test (test kit SD Bioline) was carried out on the latter to determine H.pylori infection. Ethical approval, consent and assent (for children above 8 years of age) were obtained. Data was entered using EPI DATA version 3.1 and analysed using STATA version 12.0. H. pylori prevalence was determined as a proportion of children with a positive stool test expressed as a percentage. Adjusted Odds ratios (aOR) were used to determine factors associated with H.pylori infection.Results H.pylori infection was detected in 47.7% (176/379), 95% CI (42.9-53.1) of the cases. Having epigastric pain was independently associated with H.pylori infection; aOR 2.22, 95%CI: (1.1 – 4.6), p-value= 0.03 . Pneumococcal vaccination aOR 0.41, 95% (CI 0.2-0.9; p=0.019 ) or H.pyroli combination therapy aOR 0.183, 95% (CI 0.1- 0.6; p=0.006 ) were protective against H.pylori. Recurrent abdominal pain did not predict H.pyroli infection. Conclusions H.pylori infection was common among children with sickle cell anemia and was independently associated with epigastric pain but not recurrent pain. Pneumococcal vaccination and combination H. pylori treatment were protective against the infection. Screening for H.Pylori should be carried out in sickle cell anaemia children with epigastric pain.

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