M.441 Lipid profile and number of cardiovascular risk factors (CVRF) in the prevencat study

Abstract Objectives Lipid profiles appear to be altered in SLE patients due to disease activity and inflammation. Cholesterol efflux capacity (CEC) is the ability of high-density lipoprotein cholesterol to accept cholesterol from macrophages. CEC has been linked to cardiovascular events in the general population and is impaired in SLE patients. The aim of this study was to establish whether CEC is related to subclinical carotid atherosclerosis in SLE patients. Methods The present report is of a cross-sectional study that encompassed 418 individuals: 195 SLE patients and 223 controls. CEC, using an in vitro assay, and lipoprotein serum concentrations were assessed in patients and controls. Carotid intima-media thickness and carotid plaques were evaluated in SLE patients. A multivariable analysis was performed to study the relationship of CEC to SLE-related data, lipid profile and subclinical carotid atherosclerosis. Results CEC was downregulated in SLE patients [8.1 (4.2) % vs 16.9 (10.4) %, P = 0.004). This occurred independently of traditional cardiovascular risk factors, statin use or other variations in the lipid profile related to the disease. Traditional cardiovascular risk factors, both in patients and controls, and SLE-related data such as activity, severity or damage were not associated with CEC. After multivariable regression analysis including lipid profile–related molecules, CEC was inversely and independently associated with the presence of carotid plaques in SLE patients [odds ratio 0.87 (95% CI: 0.78, 0.97), P = 0.014]. Conclusion CEC is impaired in SLE patients independently of other inflammation-related lipid profile modifications that occur during the disease. CEC is associated with carotid plaques in SLE patients.

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Abnormal lipid profile and hyperinsulinaemia after a mixed meal: additional cardiovascular risk factors in young adults born preterm

Diabetologia ◽

10.1007/s00125-008-1029-5 ◽

2008 ◽

Vol 51 (7) ◽

pp. 1269-1275 ◽

Cited By ~ 22

Author(s):

J. Rotteveel ◽

M. M. van Weissenbruch ◽

J. W. R. Twisk ◽

H. A. Delemarre-Van de Waal

Keyword(s):

Risk Factors ◽

Young Adults ◽

Cardiovascular Risk ◽

Lipid Profile ◽

Cardiovascular Risk Factors ◽

Mixed Meal

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High Levels of Cardiovascular Risk Factors among Pakistanis in Norway Compared to Pakistanis in Pakistan

Journal of Obesity ◽

10.1155/2011/163749 ◽

2011 ◽

Vol 2011 ◽

pp. 1-5 ◽

Cited By ~ 7

Author(s):

Naeem Zahid ◽

Haakon E. Meyer ◽

Bernadette N. Kumar ◽

Bjørgulf Claussen ◽

Akhtar Hussain

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Lipid Profile ◽

Total Cholesterol ◽

Cardiovascular Risk Factors ◽

Additional Risk ◽

Increased Risk ◽

Males And Females ◽

Diabetes And Obesity

Objectives. Previous studies have shown that the Norwegian-Pakistanis had considerably higher prevalence for diabetes and obesity compared to Norwegians. We studied the additional risk of obesity, dyslipidemia, and hypertension among Pakistanis in Norway compared to Pakistanis living in Pakistan.Method. 770 Norwegian-Pakistani adults (53.9% men and 46.1% women) born in Pakistan from two surveys conducted in Norway between 2000 and 2002 were compared with a sample of 1230 individuals (29.1% men and 70.9% women) that participated in a survey in Pakistan in 2006.Results. Both populations had similar height, but Norwegian-Pakistanis had considerably higher mean weight. Of the Norwegian-Pakistanis, 56% of the males and 40% of the females had a BMI above 25 kg/m2, as opposed to 30% and 56% in Pakistan, for males and females, respectively. Norwegian-Pakistanis had higher total cholesterol.Conclusion. Obesity and an unfavourable lipid profile were widely prevalent in both populations; the highest level was recorded amongst those living in Norway. The increased risk for obesity and dyslipidemia may be ascribed to change of lifestyle after migration.

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Atherogenic lipid profile and cardiovascular risk factors in HIV-infected patients (Nétar Study)

International Journal of STD & AIDS ◽

10.1258/095646205774357398 ◽

2005 ◽

Vol 16 (10) ◽

pp. 677-680 ◽

Cited By ~ 30

Author(s):

J Santos ◽

R Palacios ◽

M González ◽

J Ruiz ◽

M Márquez

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Lipid Profile ◽

Cardiovascular Risk Factors ◽

Atherogenic Lipid Profile ◽

Atherogenic Lipid

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Deranged Lipid Profile: A Cardiovascular Risk Factors among Adolescents

Pediatric Education and Research ◽

10.21088/per.2321.1644.3315.3 ◽

2015 ◽

Vol 3 (3) ◽

pp. 97-105

Author(s):

Pranam G.M. ◽

◽

Usha Pranam G. ◽

Tejesh S. ◽

Manjunath G.A. ◽

...

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Lipid Profile ◽

Cardiovascular Risk Factors

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The Effect of Anethum Graveolens L. (Dill) on Lipid Profile in Adults with Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis of Controlled Clinical Trials

Critical Comments in Biomedicine ◽

10.18502/ccb.v2i1.5870 ◽

2021 ◽

Author(s):

Anahita Mansoori ◽

Zahra Salimi ◽

Seyyed Ahmad Hosseini ◽

Razie Hormoznejad ◽

Maryam Asadi

Keyword(s):

Risk Factors ◽

Systematic Review ◽

Clinical Trials ◽

Cardiovascular Risk ◽

Lipid Profile ◽

Cardiovascular Risk Factors ◽

Meta Analysis ◽

Controlled Clinical Trials ◽

Anethum Graveolens ◽

Randomized Controlled

Background: Several randomized clinical trials (RCTs) has assessed the effect of Anethum graveolens L. (AG) or dill supplementation on lipid profile in adults with cardiovascular risk factors with different results. Therefore, we decided to conduct a systematic review and meta-analysis regarding the available randomized controlled trials to assess AG supplementation's efficacy on lipid profile in adults with cardiovascular risk factors. Methods: PubMed, Embase, Cochrane's database, Ovid, Web of Science, ProQuest, Scopus, and Google Scholar were searched to find relevant articles investigating the effect of AG on the lipid profile of adults with risk factors for cardiovascular disease up to December 2020. Six trials with seven treatment armsmet the inclusion criteria. A random-effects model was used in the meta-analysis. To test heterogeneity, I2 statistics and Cochrane Q test were applied. Results: The results reported a significant improving effect of AG on TG [WMD = -29.20, 95% confidence interval (CI): -34.73,-23.68 mg/dL, p < 0.001], TC (WMD = -16.46, 95%CI: -21.54,-11.39 mg/dL, p < 0.001), LDL-C (WMD = -13.90, 95%CI: -16.08, -11.72 mg/dL, p < 0.001), and HDL-C (WMD = 4.01, 95%CI: 3.48, 4.54 mg/dL, p < 0.001). Conclusion: This meta-analysis of randomized controlled clinical trials revealed that consuming AG extract for more than six weeks might improve lipid profile in adults with cardiovascular risk factors.

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