scholarly journals The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of cDNA from tracheal and gastric tissues

1990 ◽  
Vol 265 (33) ◽  
pp. 20455-20462
Author(s):  
N P Gerard ◽  
R L Eddy ◽  
T B Shows ◽  
C Gerard
Keyword(s):  
Molecular Cloning ◽  
Neurokinin A ◽  
Chromosome Localization ◽  
Substance K

scholarly journals The metabolism of neuropeptides. Neurokinin A (substance K) is a substrate for endopeptidase-24.11 but not for peptidyl dipeptidase A (angiotensin-converting enzyme)

1985 ◽  
Vol 231 (2) ◽  
pp. 357-361 ◽  
Author(s):  
N M Hooper ◽  
A J Kenny ◽  
A J Turner
Keyword(s):  
Substance P ◽  
Selective Inhibitor ◽  
Synaptic Membranes ◽  
Neurokinin A ◽  
Pig Kidney ◽  
Endopeptidase 24.11 ◽  
The Family ◽  
General Capacity ◽  
Substance K ◽  
Hydrolysis Of

Both endopeptidase-24.11 and peptidyl dipeptidase A have previously been shown to hydrolyse the neuropeptide substance P. The structurally related peptide neurokinin A is also shown to be hydrolysed by pig kidney endopeptidase-24.11. The identified products indicated hydrolysis at two sites, Ser5-Phe6 and Gly8-Leu9, consistent with the known specificity of the enzyme. The pattern of hydrolysis of neurokinin A by synaptic membranes prepared from pig striatum was similar to that observed with purified endopeptidase-24.11, and hydrolysis was substantially abolished by the selective inhibitor phosphoramidon. Peptidyl dipeptidase A purified from pig kidney was shown to hydrolyse substance P but not neurokinin A. It is concluded that endopeptidase-24.11 has the general capacity to hydrolyse and inactivate the family of tachykinin peptides, including substance P and neurokinin A.

Distribution of substance K (neurokinin A) in the brain and peripheral tissues of rats

1986 ◽  
Vol 369 (1-2) ◽  
pp. 400-404 ◽  
Author(s):  
Yukio Takano ◽  
Akira Nagashima ◽  
Haruyuki Masui ◽  
Kenji Kuromizu ◽  
Hiro-o Kamiya
Keyword(s):  
Neurokinin A ◽  
Peripheral Tissues ◽  
Substance K ◽  
The Brain

Distinct binding sites for substance P and neurokinin A (substance K): Co-transmitters in rat brain

Peptides ◽  
1985 ◽  
Vol 6 (2) ◽  
pp. 343-345 ◽  
Author(s):  
C.W. Shults ◽  
S.H. Buck ◽  
E. Burcher ◽  
T.N. Chase ◽  
T.L. O'Donohue
Keyword(s):  
Substance P ◽  
Rat Brain ◽  
Binding Sites ◽  
Neurokinin A ◽  
Substance K

Evidence that neurokinin A (substance K) neurons project from the striatum to the substantia nigra in rats

1987 ◽  
Vol 77 (1) ◽  
pp. 103-108 ◽  
Author(s):  
Akira Nagashima ◽  
Yukio Takano ◽  
Harunori Masui ◽  
Hiro-o Kamiya
Keyword(s):  
Substantia Nigra ◽  
Neurokinin A ◽  
Substance K

scholarly journals Molecular Cloning of the cDNA and Chromosome Localization of the Gene for Human Ubiquitin-conjugating Enzyme 9

1996 ◽  
Vol 271 (40) ◽  
pp. 24811-24816 ◽  
Author(s):  
Zhao-Yi Wang ◽  
Qing-Qing Qiu ◽  
Wolfgang Seufert ◽  
Takahiro Taguchi ◽  
Joseph R. Testa ◽  
...  
Keyword(s):  
Molecular Cloning ◽  
Chromosome Localization ◽  
Human Ubiquitin ◽  
Ubiquitin Conjugating Enzyme ◽  
Conjugating Enzyme
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