Determination of disopyramide and its mono-N-dealkylated metabolite in blood serum and urine

1975 ◽  
Vol 106 (1) ◽  
pp. 151-158 ◽  
Author(s):  
T.C. Hutsell ◽  
S.J. Stachelski
Keyword(s):  
Blood Serum ◽  
Serum And Urine

Automated enzymic determination of ethanol in blood, serum, and urine with a miniature centrifugal analyzer.

1976 ◽  
Vol 22 (6) ◽  
pp. 802-805 ◽  
Author(s):  
T P Hadjiioannou ◽  
S I Hadjiioannou ◽  
J Avery ◽  
H V Malmstadt
Keyword(s):  
Blood Serum ◽  
Reaction Rates ◽  
Rate Of Change ◽  
Coefficients Of Variation ◽  
Analytical Recovery ◽  
Rate Method ◽  
Relative Errors ◽  
Urine Specimens ◽  
Serum And Urine

Abstract We describe an automated spectrophotometric reaction-rate method for determination of ethanol in serum and urine with a miniature centrifugal analyzer. The theanol is selectively oxidized in the presence of alcochol dehydrogenase and NAD+ to form NADH, which is measured by the rate of change of its absorbance. Reaction rates are determined automatically, and unknown concentrations are calculated from a computer-generated working curve based on aqueous ethanol standards. Blood, serum, or urine specimens need not be deproteinized. The method permits duplicate analysis of at least 30 samples per hour. Coefficients of variation and relative errors are about 2-3% for ethanol concentrations of 0.3-3.0 mug per 2 mul of sample. Analytical recovery of ethanol added to serum is 92-103% (average, 98.5%). Comparisons with distillation-oxidation, gas-chromatographic, and conventional enzymic procedures give satisfactory agreement.

Spectrophotofluorometric Determination of Salicylamide in Blood Serum and Urine

1971 ◽  
Vol 60 (7) ◽  
pp. 1092-1095 ◽  
Author(s):  
Stephen A. Veresh ◽  
Foo Song Hom ◽  
John J. Miskel
Keyword(s):  
Blood Serum ◽  
Serum And Urine
Sign in / Sign up

Export Citation Format

Share Document