Chromatographic separation of racemic amino acids by use of chiral crown ether-coated reversed-phase packings

1987 ◽  
Vol 405 ◽  
pp. 145-153 ◽  
Author(s):  
Toshio Shinbo ◽  
Tomohiko Yamaguchi ◽  
Koichiro Nishimura ◽  
Masaaki Sugiura
Keyword(s):  
Amino Acids ◽  
Crown Ether ◽  
Chromatographic Separation ◽  
Reversed Phase ◽  
Chiral Crown Ether

ENANTIOMER RESOLUTION OF AMINO ACIDS BY A POLYMER-SUPPORTED LIQUID MEMBRANE CONTAINING A CHIRAL CROWN ETHER

1985 ◽  
Vol 14 (10) ◽  
pp. 1549-1552 ◽  
Author(s):  
Tomohiko Yamaguchi ◽  
Koichiro Nishimura ◽  
Toshio Shinbo ◽  
Masaaki Sugiura
Keyword(s):  
Amino Acids ◽  
Crown Ether ◽  
Liquid Membrane ◽  
Supported Liquid Membrane ◽  
Chiral Crown Ether ◽  
Enantiomer Resolution ◽  
Polymer Supported

scholarly journals USING OPTICALLY ACTIVE CHIRAL CROWN ETHER AT ENANTIOMERIC SEPARATION OF AMINES

2021 ◽  
pp. 59-62
Author(s):  
U.A. Hasanova ◽  
◽  
Z.O. Qahramanova ◽  
P.F. Huseynova ◽  
◽  
...  
Keyword(s):  
Crown Ether ◽  
Optical Activity ◽  
Column Chromatography ◽  
Chromatographic Separation ◽  
Enantiomeric Separation ◽  
Optically Active ◽  
Racemic Mixture ◽  
Chiral Crown Ether ◽  
Physicochemical Methods ◽  
Formation Of Complexes

The synthesized S-enantiomer of the crown ether was used as an adsorbent to separate the racemic mixture of L-alanine ether of phenamine into individual diastereomers by column chromatography. Chromatographic separation occurred due to the formation of complexes of different stability between diastereomers and optically selective adsorbents on a host-guest principle. The separated diastereomers were converted into enantiomers by hydrolysis. The structure and optical activity of the synthesized crown ether and separated enantiomers were investigated by physicochemical methods

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