Enantiomeric separation of tocainide and its analogues on an optically active crown ether-based stationary phase by liquid chromatography

2003 ◽  
Vol 996 (1-2) ◽  
pp. 233-237 ◽  
Author(s):  
Myung Ho Hyun ◽  
Hye Jung Min ◽  
Yoon Jae Cho
Keyword(s):  
Liquid Chromatography ◽  
Crown Ether ◽  
Stationary Phase ◽  
Enantiomeric Separation ◽  
Optically Active

scholarly journals USING OPTICALLY ACTIVE CHIRAL CROWN ETHER AT ENANTIOMERIC SEPARATION OF AMINES

2021 ◽  
pp. 59-62
Author(s):  
U.A. Hasanova ◽  
◽  
Z.O. Qahramanova ◽  
P.F. Huseynova ◽  
◽  
...  
Keyword(s):  
Crown Ether ◽  
Optical Activity ◽  
Column Chromatography ◽  
Chromatographic Separation ◽  
Enantiomeric Separation ◽  
Optically Active ◽  
Racemic Mixture ◽  
Chiral Crown Ether ◽  
Physicochemical Methods ◽  
Formation Of Complexes

The synthesized S-enantiomer of the crown ether was used as an adsorbent to separate the racemic mixture of L-alanine ether of phenamine into individual diastereomers by column chromatography. Chromatographic separation occurred due to the formation of complexes of different stability between diastereomers and optically selective adsorbents on a host-guest principle. The separated diastereomers were converted into enantiomers by hydrolysis. The structure and optical activity of the synthesized crown ether and separated enantiomers were investigated by physicochemical methods

Poly(Crown Ether)-Modified Silica for Stationary Phase of Liquid Chromatography

1980 ◽  
Vol 13 (9) ◽  
pp. 741-750 ◽  
Author(s):  
Keiichi Kimura ◽  
Masaki Nakajima ◽  
Toshiyuki Shono
Keyword(s):  
Liquid Chromatography ◽  
Crown Ether ◽  
Stationary Phase ◽  
Modified Silica
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