Dehydroepiandrosterone Sulfate as a Digitalis Like Factor in Plasma of Healthy Human Adults

1986 ◽  
Vol 135 (3) ◽  
pp. 664-664
Author(s):  
S. Vasdev ◽  
L. Longerich ◽  
E. Johnson ◽  
D. Brent ◽  
M.H. Gault
2019 ◽  
Vol 76 (5) ◽  
pp. 391-400
Author(s):  
Anna Reimann ◽  
Rudolf Beyer ◽  
Rebekka Mumm ◽  
Christiane Scheffler

Vaccine ◽  
2004 ◽  
Vol 22 (23-24) ◽  
pp. 3182-3186 ◽  
Author(s):  
Karen S Slobod ◽  
Jerry L Shenep ◽  
Jorge Luján-Zilbermann ◽  
Kim Allison ◽  
Brita Brown ◽  
...  

2015 ◽  
Vol 133 ◽  
pp. 1-6 ◽  
Author(s):  
Adrian Hase ◽  
Sophie E. Jung ◽  
Marije aan het Rot

2019 ◽  
Vol 50 (4) ◽  
pp. 1160-1168 ◽  
Author(s):  
Gani Gashi ◽  
Philipp Madoerin ◽  
Claudia I. Maushart ◽  
Regina Michel ◽  
Jaël‐Rut Senn ◽  
...  

1997 ◽  
Vol 352 (1354) ◽  
pp. 743-750 ◽  
Author(s):  
H. R. Heekeren ◽  
H. Obrig ◽  
R. Wenzel ◽  
K. Eberle ◽  
J. Ruben ◽  
...  

Using near–infrared spectroscopy, we investigated the time–course of the concentrations of oxygenated haemoglobin, [oxy–Hb], and deoxygenated haemoglobin, [deoxy–Hb], in the occipital cortex of healthy human adults during sustained visual stimulation. Within a few seconds after stimulation (coloured dodecahedrons) we observed a decrease in [deoxy–Hb], peaking after 13 s (‘initial undershoot’). In the subsequent 1–2 min, in seven out of ten subjects, [deoxy–Hb] gradually returned to a plateau closer to the baseline level. After cessation of stimulation, there was a ‘post–stimulus overshoot’ in the concentration of deoxyhaemoglobin. There was a statistically significant correlation between the size of the ‘initial undershoot’ and the ‘post–stimulus overshoot’. The concentration of oxyhaemoglobin increased upon functional activation. However, in the mean across all subjects there was no initial overshoot. After approximately 19 s it reached a plateau and remained constantly elevated throughout the activation period. After cessation of activation there was a ‘post–stimulus undershoot’ of oxyhaemoglobin. It is important to consider the time–course of haemoglobin oxygenation when interpreting functional activation data, especially those data obtained with oxygenation–sensitive methods, such as BOLD contrast fMRI.


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