Hydrodynamics of the Normal Multicalyceal Pyeloureter in Pigs: The Pelvic Pressure Response to Increasing Flow Rates, Its Normal Ranges and Intra-Individual Variations

1985 ◽  
Vol 133 (4) ◽  
pp. 704-708 ◽  
Author(s):  
J. Mortensen ◽  
J.C. Djurhuus
1976 ◽  
Vol 22 (8) ◽  
pp. 1288-1291 ◽  
Author(s):  
R A Chalmers ◽  
M J Healy ◽  
A M Lawson ◽  
R W Watts

Abstract We have assessed individual variations in urinary acidic metabolite excretion and the effects of extreme alterations in dietary composition on these metabolites in selected normal persons who we considered representative of the general ambulant normal population. Extreme dietary alterations produced relatively small changes in the patterns or amounts of metabolite excretion, but large individual within-subject variations were observed. Our results indicate that variation in the ranges of excretion for the normal population mainly depend on individual metabolic variations rather than on dietary factors, and provide a basis for the assessment of the normal ranges determined from population surveys. Our results are discussed in relation to previous studies on the variability of urinary acidic metabolite excretion in man.


1972 ◽  
Vol 18 (3) ◽  
pp. 244-249 ◽  
Author(s):  
Eugene K Harris ◽  
David L DeMets

Abstract When healthy individuals are surveyed to estimate the "normal range" of some measured variable, generally only a single determination of the variable is obtained for each person. The distribution of such values reflects intra-individual variations, (including analytic deviations) as well as the differences among individuals with respect to such parameters as mean or variance. These underlying sources of variation have been expressed in a conditional probability model from which general equations have been derived showing the effects of these variations on the shape parameters (skewness and kurtosis) of a single-sample distribution. These results may help to explain the shape of a given distribution. More generally, they imply that methods of calculating normal ranges would benefit from a study of various mathematical transformations that could convert distributions of almost any shape to approximately gaussian form. Data from recent blood-chemistry studies are used to compare observed shape statistics with those calculated from the model.


2012 ◽  
Vol 22 (01n02) ◽  
pp. 87-93
Author(s):  
TODD SAUNDERS ◽  
SHOHEI KURODA ◽  
TSUYOSHI NAKAMURA ◽  
TOMOMI YAMADA ◽  
KOICHIRO SERA ◽  
...  

Hair mineral content has become a useful biomarker to measure exposure to elements both safe and unsafe. To promote the use of hair mineral volumes in clinical practice, it would seem crucial to first determine their normal ranges by the statistical analysis of hair minerals sampled from a large healthy population. This paper used Proton Induced X-ray emissions (PIXE) to measure mineral concentrations in the hair of 842 mother-infant pairs. The data were then statistically analyzed to determine their normal ranges and categorized into 4 groups based on distributional characteristics. Intra-individual variations are also identified and discussed with regard to risk analysis.


1972 ◽  
Vol 12 (06) ◽  
pp. 499-507 ◽  
Author(s):  
C.H. Kuo

Abstract This theoretical research deals with the use of periodic variable-rate flow tests for obtaining reservoir parameters. During the test period, the flow rate at a test well is varied periodically, either sinusoidally or in a repeated sequence of constant flow rates, while the accompanying resultant pressures are measured at the test well itself (single-well test) and/or at nearby responding wells (multiwell test). Theoretical pressure equations due to these periodic rates of fluid flow at a test well are derived. Methods of interpreting the test results are proposed. For the general periodic variable-rate flow tests, reservoir properties can be calculated from the slope and the intercept in a linear plot of the measured pressure responses vs a known time function. In cases where a sinusoidal rate is imposed at a test well, it is only necessary to measure the maximum pressure response amplitude and the phase lag in order to calculate the formation parameters. A single-well test yields the kh value and the skin factor. A multiwell test yields the average kh value and the storage capacity between wells. When the same wells are used, differences in the kh values from these tests would be indicative of reservoir heterogeneities. Since the tests can be carried out simultaneously, this combination provides more information about the reservoir than would be available from either test alone. A frequency analysis of the pressure responses also offers the possibility of determining the heterogeneity distribution within the reservoir. Introduction Pressure buildup analysis is one of the most common means of determining reservoir properties from well tests. The method is operationally simple, and the theory is well developed. Unfortunately, interpretation of pressure buildup test results is often difficult for reservoirs of very high or very low permeability. Another method involving use of two or more wells to evaluate reservoir properties is the interference test. This method, however, has not been used often because of the long interruption of normal field operations usually required to obtain useful data. To eliminate this drawback, a new method of interference testing, called pulse testing, recently was proposed by Johnson et al. The test utilizes a sensitive pressure gauge at a responding well to measure the response generated by a series of flow-rate changes at a test well. A key feature of these pulse test is that, because of the cyclic nature of the pressure response, the arrival of the response can be distinguished from the background pressure. Thus, the time required to obtain a diagnostic pressure response is very short (usually a few hours or less) compared with conventional interference testing. The field applications of this pulse-testing technique, made to determine the distribution of reservoir properties, also have been reported. This theoretical research investigates the use of periodically varying flow rates to obtain reservoir parameters. Two types of flow rates, sinusoidal and periodic multiple rates, are considered in this study. The pressure response can be measured simultaneously at both the test well and a nearby responding well. In this report, when the pressure response is measured at the test well, the test will be called a "single-well test"; if the pressure is measured at a responding well some distance away from the test well, the test will be termed a "multiwell test". Theoretical pressure response equations for these tests are derived in this report. Interpretation methods for evaluating the formation parameters are also developed. The advantages and the drawbacks of these tests will be discussed. THEORETICAL DEVELOPMENT In a manner analogous to that used in developing the theoretical pressure response for many other types of well tests, the reservoir is considered to be a homogeneous and isotropic porous medium. This reservoir has a finite thickness h. The porosity phi and the permeability k are assumed to be constants. A test well is located in this porous medium of infinite radial extent. SPEJ P. 499ˆ


Author(s):  
R. Chen

ABSTRACT:Cutaneous reflexes in the upper limb were elicited by stimulating digital nerves and recorded by averaging rectified EMG from proximal and distal upper limb muscles during voluntary contraction. Distal muscles often showed a triphasic response: an inhibition with onset about 50 ms (Il) followed by a facilitation with onset about 60 ms (E2) followed by another inhibition with onset about 80 ms (12). Proximal muscles generally showed biphasic responses beginning with facilitation or inhibition with onset at about 40 ms. Normal ranges for the amplitude of these components were established from recordings on 22 arms of 11 healthy subjects. An attempt was made to determine the alterent fibers responsible for the various components by varying the stimulus intensity, by causing ischemic block of larger fibers and by estimating the afferent conduction velocities. The central pathways mediating these reflexes were examined by estimating central delays and by studying patients with focal lesions


Author(s):  
Billy Irwin

Abstract Purpose: This article discusses impaired prosody production subsequent to traumatic brain injury (TBI). Prosody may affect naturalness and intelligibility of speech significantly, often for the long term, and TBI may result in a variety of impairments. Method: Intonation, rate, and stress production are discussed in terms of the perceptual, physiological, and acoustic characteristics associated with TBI. Results and Conclusions: All aspects of prosodic production are susceptible to the effects of damage resulting from TBI. There are commonly associated prosodic impairments; however, individual variations in specific aspects of prosody require detailed analysis.


1987 ◽  
Vol 57 (03) ◽  
pp. 263-268 ◽  
Author(s):  
P Toulon ◽  
C Jacquot ◽  
L Capron ◽  
M -O Frydman ◽  
D Vignon ◽  
...  

SummaryHeparin enhances the inhibition rate of thrombin by both antithrombin III (AT III) and heparin cofactor II (HC II). We studied the activity of these two plasma proteins in patients with chronic renal failure (CRF) undergoing regular hemodialysis as their heparin requirements varied widely. In 77 normal blood donors, normal ranges (mean ± 2 SD) were 82-122% for AT III and 65-145% for HC II. When compared with these controls 82 dialyzed CRF patients had a subnormal AT III activity and a significantly (p <0.001) lower HC II activity. To evaluate the effect of hemodialysis we compared AT III, HC II and total proteins in plasma before and after dialysis in. 24 patients (12 with normal and 12 with low basal HC II activity). AT III and HC II activities significantly (p <0.001) increased in absolute value. When related to total plasma proteins, in order to suppress the influence of hemoconcentration induced by dialysis, AT III decreased significantly (p <0.01) whereas HC II increased slightly but significantly (p <0.01) in the 12 patients with low initial HC II activity. The decrease of AT III induced by heparin administrated during dialysis is likely to account for this relative decrease of AT III activity. A modification of the distribution of both HC II and heparin between the vascular wall and the circulating blood is evoked to explain the relative increase in HC II activity and the need for higher heparin dosage in patients with low HC II levels.


1995 ◽  
Vol 74 (05) ◽  
pp. 1271-1275 ◽  
Author(s):  
C M A Henkens ◽  
V J J Bom ◽  
W van der Schaaf ◽  
P M Pelsma ◽  
C Th Smit Sibinga ◽  
...  

SummaryWe measured total and free protein S (PS), protein C (PC) and factor X (FX) in 393 healthy blood donors to assess differences in relation to sex, hormonal state and age. All measured proteins were lower in women as compared to men, as were levels in premenopausal women as compared to postmenopausal women. Multiple regression analysis showed that both age and subgroup (men, pre- and postmenopausal women) were of significance for the levels of total and free PS and PC, the subgroup effect being caused by the differences between the premenopausal women and the other groups. This indicates a role of sex-hormones, most likely estrogens, in the regulation of levels of pro- and anticoagulant factors under physiologic conditions. These differences should be taken into account in daily clinical practice and may necessitate different normal ranges for men, pre- and postmenopausal women.


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