Isolation and synthesis of 1-methylisoguanosine, a potent pharmacologically active constituent from the marine sponge

1980 ◽  
Vol 21 (6) ◽  
pp. 567-568 ◽  
Author(s):  
Ronald J. Quiann ◽  
Richard P. Gregson ◽  
Alan F. Cook ◽  
Robert T. Bartlett
1983 ◽  
Vol 36 (1) ◽  
pp. 165 ◽  
Author(s):  
R Kazlauskas ◽  
PT Murphy ◽  
RJBJA Wells ◽  
DD Jamieson

4-Amino-5-bromopyrrolo[2,3-d]pyrimidine has been isolated from a sponge (Echinodictyum sp.). The pharmacologically active constituent of the red alga Hypnea valendiae has been identified as 4-amino-7-(5'-deoxyribos-1'β-yl)-5-iodopyrrolo[2,3-d]pyrimidine (7). A second nucleoside, tentatively assigned as the 1'α isomer of (7), has also been isolated.


1980 ◽  
Vol 45 (20) ◽  
pp. 4020-4025 ◽  
Author(s):  
Alan F. Cook ◽  
Robert T. Bartlett ◽  
Richard P. Gregson ◽  
Ronald J. Quinn

2020 ◽  
Vol 2 (1) ◽  
pp. 52-66
Author(s):  
Wendy Alexander Tanod ◽  
Muliadin ◽  
Yeldi S. Adel ◽  
Didit Kustantio Dewanto

Marine organisms are a source of natural products and produce compounds with a molecular structure that is unique and useful. Thousands of new compounds have biological activitity for anticancer, antiviral, and antimicrobial. This compounds isolated from various marine organism, including from marine-derived fungi. Investigation of chemical compounds from marine-derived fungi isolated from sponge has increased steadily, indicating the important role of marine-derived fungi in the discovery of drug compounds. The sponge has produced various kinds of fungi, which have reported to provide a variety of pharmacologically active metabolites and structurally diverse. Study literature showed that many fungal genera isolated from the marine sponge dominated the genus Acremonium, Aspergillus, Penicillium, Phoma, and Fusarium. The high proportion of genera and new compounds showed that the fungi isolated from the sponge could develop.


Author(s):  
Alexandra E. Kelly-Hunt ◽  
Aman Mehan ◽  
Sarah Brooks ◽  
Miron A. Leanca ◽  
Jack E. D. McKay ◽  
...  

1982 ◽  
Vol 30 (10) ◽  
pp. 3544-3547 ◽  
Author(s):  
HIROYUKI KIKUCHI ◽  
YASUMASA TSUKITANI ◽  
TOSHITAKA MANDA ◽  
TAKASHI FUJII ◽  
HAJIME NAKANISHI ◽  
...  

1981 ◽  
Vol 12 (4) ◽  
Author(s):  
A. F. COOK ◽  
R. T. BARTLETT ◽  
R. P. GREGSON ◽  
R. J. QUINN

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
I Kajahn ◽  
Z Yu ◽  
G Lang ◽  
R Schmaljohann ◽  
JF Imhoff

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