Thermal Stability of Collagen Triple Helix

2009 ◽  
pp. 211-232 ◽  
Author(s):  
Yujia Xu
Keyword(s):  
Thermal Stability ◽  
Triple Helix ◽  
Collagen Triple Helix ◽  
Thermal Stability Of

scholarly journals Anionic surfactant sulfate dodecyl sodium (SDS)-induced thermodynamics and conformational changes of collagen by ultrasensitive microcalorimetry

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Jie Zhang ◽  
Chunhua Wang ◽  
Fengteng Zhang ◽  
Wei Lin
Keyword(s):  
Thermal Stability ◽  
Conformational Changes ◽  
Triple Helix ◽  
Striking Difference ◽  
Thermal Transition ◽  
Scanning Calorimetry ◽  
Helix Structure ◽  
Stabilizing Effect ◽  
Collagen Molecules ◽  
Thermal Stability Of

Abstract In this communication, sulfate dodecyl sodium (SDS)-induced thermodynamics and conformational changes of collagen were studied. We used ultrasensitive differential scanning calorimetry (US-DSC) to directly monitor the thermal transition of collagen in the presence of SDS. The results show that SDS affects the conformation and thermal stability of collagen very differently depending on its concentrations. At CSDS ≤ 0.05 mM, the enhanced thermal stability of collagen indicates the stabilizing effect by SDS. However, a further increase of SDS leads to the denaturation of collagen, verifying the well-known ability of SDS to unfold proteins. This striking difference in thermodynamics and conformational changes of collagen caused by SDS concentrations can be explained in terms of their interactions. With increasing SDS, the binding of SDS to collagen can be dominated by electrostatic interaction shifting to hydrophobic interaction, and the latter plays a key role in loosening and unfolding the triple-helix structure of collagen. The important finding in the present study is the stabilizing effect of SDS on collagen molecules at extreme low concentration. Graphical abstract

A recombinant homotrimer of type I procollagen that lacks the central two D-periods. The thermal stability of the triple helix is decreased by 2 to 4 °C

1997 ◽  
Vol 16 (5) ◽  
pp. 245-253 ◽  
Author(s):  
Khaja Zafarullah ◽  
Aleksander L. Sieron ◽  
Andrzej Fertala ◽  
Gerard Tromp ◽  
Helena Kuivaniemi ◽  
...  
Keyword(s):  
Thermal Stability ◽  
Triple Helix ◽  
Type I ◽  
Type I Procollagen ◽  
Thermal Stability Of

The Ordered Phase Formation in Ti-Al-Ga Alloys

1970 ◽  
Vol 28 ◽  
pp. 440-441
Author(s):  
Shiro Fujishiro ◽  
Harold L. Gegel
Keyword(s):  
Thermal Stability ◽  
High Temperature ◽  
Titanium Alloys ◽  
Growth Kinetics ◽  
Stoichiometric Composition ◽  
Good Potential ◽  
Alpha Titanium ◽  
Cold Rolled ◽  
Kinetics Of ◽  
Thermal Stability Of

Ordered-alpha titanium alloys having a DO19 type structure have good potential for high temperature (600°C) applications, due to the thermal stability of the ordered phase and the inherent resistance to recrystallization of these alloys. Five different Ti-Al-Ga alloys consisting of equal atomic percents of aluminum and gallium solute additions up to the stoichiometric composition, Ti3(Al, Ga), were used to study the growth kinetics of the ordered phase and the nature of its interface.The alloys were homogenized in the beta region in a vacuum of about 5×10-7 torr, furnace cooled; reheated in air to 50°C below the alpha transus for hot working. The alloys were subsequently acid cleaned, annealed in vacuo, and cold rolled to about. 050 inch prior to additional homogenization

Sign in / Sign up

Export Citation Format

Share Document