A B Cell line from a patient with pure red cell aplasia produces an immunoglobulin that suppresses erythropoiesis

1991 ◽  
Vol 61 (1) ◽  
pp. 18-28 ◽  
Author(s):  
Masayuki Nagasawa ◽  
Hiroji Okawa ◽  
Junichi Yata
2002 ◽  
Vol 119 (1) ◽  
pp. 125-127 ◽  
Author(s):  
Kevin W. Song ◽  
Peter Mollee ◽  
Bruce Patterson ◽  
William Brien ◽  
Michael Crump

2013 ◽  
Vol 2013 (nov14 1) ◽  
pp. bcr2013201027-bcr2013201027 ◽  
Author(s):  
P. Dharmshaktu ◽  
N. Gupta ◽  
D. K. Dhanwal

2014 ◽  
Vol 93 (9) ◽  
pp. 1611-1612
Author(s):  
Maria Ilaria Del Principe ◽  
Mariagiovanna Cefalo ◽  
Francesco Buccisano ◽  
Lucia Anemona ◽  
Chiara Sarlo ◽  
...  

2004 ◽  
Vol 5 (6) ◽  
pp. 546-547 ◽  
Author(s):  
Despina Pantelidou ◽  
Costas Tsatalas ◽  
Dimitris Margaritis ◽  
Vasiliki Kaloutsi ◽  
Emmanuel Spanoudakis ◽  
...  

2005 ◽  
Vol 33 (4) ◽  
pp. 460-466 ◽  
Author(s):  
Y Hatta ◽  
Y Kura ◽  
T Yano ◽  
H Ushiyama ◽  
M Sugitani ◽  
...  

We describe an unusual case of B-cell neoplasm accompanied by pure red cell aplasia (PRCA) and myelofibrosis in a 67-year-old male presenting with severe anaemia. A few unclassified, myeloperoxidase-negative blastoid cells were seen on bone marrow aspiration, and erythroid cell hypoplasia and myelofibrosis on bone marrow biopsy. An autoimmune PRCA was suspected, as serum CH50, C3 and C4 levels were consistently low. Ciclosporin was effective in treating the anaemia, but anaemia returned when the drug was discontinued. Thirteen months later, the patient was admitted with pleural effusion and ascites that contained monoclonal CD19+ CD20+ immature blast cells with a complex karyotype, thought to be neoplastic B-cells. The unclassified blastoid cells seen earlier may therefore have been from the same origin. The patient deteriorated rapidly and died. Only one case of non-Hodgkin's lymphoma with PRCA and myelofibrosis has been reported previously. We discuss the possibility that dysregulated T-cells induced by neoplastic B-cells may have given rise to concomitant PRCA and myelofibrosis.


2006 ◽  
Vol 30 (1) ◽  
pp. 109-114 ◽  
Author(s):  
Kalyani Narra ◽  
Hossein Borghaei ◽  
Tahseen Al-Saleem ◽  
Martin Höglund ◽  
Mitchell R. Smith

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