Comparison of Conservative and Dynamic Management of Premature Rupture of Membranes/Premature Labor Syndrome: New Approaches to the Delivery of Infants Which May Minimize the Need for Intensive Care

1980 ◽  
Vol 7 (1) ◽  
pp. 17-31 ◽  
Author(s):  
David J. Nochimson ◽  
Roy H. Petrie ◽  
Bhavesh L. Shah ◽  
Narasingrao Pampati ◽  
Diane Brunelle
Keyword(s):  
Intensive Care ◽  
Premature Labor ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Dynamic Management ◽  
New Approaches

scholarly journals Epidemiological characteristics of neonatal admissions in a public maternity / Características epidemiológicas das internações neonatais em uma maternidade pública / Características epidemiológicas de admisión neonatal en una maternidad..

2018 ◽  
Vol 6 (4) ◽  
pp. 28
Author(s):  
Danubia Jacomo Da Silva Cardoso ◽  
Beatriz Schumacher
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Medical Records ◽  
Preterm Labor ◽  
Neonatal Intensive Care ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Maternal Complications ◽  
Epidemiological Characteristics

Descriptive retrospective Research with quantitative approach. Aims: Meet the epidemiological characteristics of hospitalization in Neonatal intensive care unit, relating them to the possible maternal factors, in a public maternity in southern Brazil. Performed with newborns that they put in the NICU, forwarded with the clinical summary to the Municipal program precious baby. The data were collected, with the following variables: maternal age, type of birth, number of pre-natal consultations, complications in pregnancy, and number of days of hospitalization in neonatal intensive care unit, in the period from January to December 2013. Were analyzed medical records 72, prematurity was the most prevalent with 61% of the babies, and their consequences such as the use of mechanical ventilation and apneas 55.5% were repeated and 52.7% respectively. Among the most frequent maternal complications was observed the Preterm Labor (31.3%) and premature rupture of membranes (23.8%). Thus the identification of the factors that lead to preterm labor and premature rupture of membranes, could meet the maternal background and consequently reduce the prematurity and low birth weight.

scholarly journals Management of Gestation with Abnormal Invasive Placenta Complicated by an Extra-preterm Premature Rupture of Membranes in a Tertiary Perinatal Centre

2020 ◽  
Vol 27 (3) ◽  
pp. 113-124
Author(s):  
N. V. Mingaleva ◽  
T. B. Makukhina ◽  
E. S. Lebedenko ◽  
T. A. Anikina ◽  
M. D. Kotleva ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Blood Loss ◽  
Multidisciplinary Approach ◽  
Second Phase ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Increased Risk ◽  
Invasive Placenta

Aim. Assessment of methods for prolonging gestation after an extra-preterm premature rupture of membranes (PROM) in a patient with abnormal invasive placenta and the efficacy of a multidisciplinary approach for treatment of a combined obstetric pathology in a tertiary perinatal centre.Results. A clinical case is reported of PROM at 22+6 weeks’ gestation in a patient with two caesarean scars on the uterus and abnormal invasive placenta. In a tertiary perinatal centre, pregnancy was prolonged to 36+3 weeks’ term. The period between PROM and delivery was 96 days. A planned caesarean section and metroplasty were performed in the setting of temporary balloon occlusion of common iliac arteries. Blood loss was 75 mL/kg. Placenta increta without chorioamnionitis was confirmed histologically. The patient stayed in the intensive care unit for two days and was discharged home on the 8th day. The newborn was assigned the Apgar score of 6/6. For two days, ventilatory support was rendered in a neonatal intensive care unit. The newborn was diagnosed with congenital pneumonia, the first-degree hypoxic-ischemic damage of the central nervous system and transferred to the second phase of nursing.Conclusions. A multidisciplinary approach and high technology facilities in the setting of a tertiary perinatal centre allow to reduce perinatal losses and provide high-quality care to patients with an increased risk of massive blood loss with the capacity to manage organ-preserving operative delivery with full rehabilitation in the postoperative period.

scholarly journals The association between SARS-CoV-2 infection and preterm delivery: a prospective study with a multivariable analysis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Oscar Martinez-Perez ◽  
◽  
Pilar Prats Rodriguez ◽  
Marta Muner Hernandez ◽  
Maria Begoña Encinas Pardilla ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Prospective Study ◽  
Preterm Delivery ◽  
Neonatal Intensive Care ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Obstetric Morbidity ◽  
In Pregnancy

Abstract Background To determine whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, the cause of COVID-19 disease) exposure in pregnancy, compared to non-exposure, is associated with infection-related obstetric morbidity. Methods We conducted a multicentre prospective study in pregnancy based on a universal antenatal screening program for SARS-CoV-2 infection. Throughout Spain 45 hospitals tested all women at admission on delivery ward using polymerase-chain-reaction (PCR) for COVID-19 since late March 2020. The cohort of positive mothers and the concurrent sample of negative mothers was followed up until 6-weeks post-partum. Multivariable logistic regression analysis, adjusting for known confounding variables, determined the adjusted odds ratio (aOR) with 95% confidence intervals (95% CI) of the association of SARS-CoV-2 infection and obstetric outcomes. Main outcome measures: Preterm delivery (primary), premature rupture of membranes and neonatal intensive care unit admissions. Results Among 1009 screened pregnancies, 246 were SARS-CoV-2 positive. Compared to negative mothers (763 cases), SARS-CoV-2 infection increased the odds of preterm birth (34 vs 51, 13.8% vs 6.7%, aOR 2.12, 95% CI 1.32–3.36, p = 0.002); iatrogenic preterm delivery was more frequent in infected women (4.9% vs 1.3%, p = 0.001), while the occurrence of spontaneous preterm deliveries was statistically similar (6.1% vs 4.7%). An increased risk of premature rupture of membranes at term (39 vs 75, 15.8% vs 9.8%, aOR 1.70, 95% CI 1.11–2.57, p = 0.013) and neonatal intensive care unit admissions (23 vs 18, 9.3% vs 2.4%, aOR 4.62, 95% CI 2.43–8.94, p <  0.001) was also observed in positive mothers. Conclusion This prospective multicentre study demonstrated that pregnant women infected with SARS-CoV-2 have more infection-related obstetric morbidity. This hypothesis merits evaluation of a causal association in further research.

scholarly journals Safety of pregnancy in uterine fibroids

2018 ◽  
Vol 7 (8) ◽  
pp. 2985
Author(s):  
Maha Alhainiah ◽  
Elaf Aljifry ◽  
Ayman Alghamdi ◽  
Lujain Alrabghi ◽  
Abdullah Alharbi ◽  
...  
Keyword(s):  
Intrauterine Growth Retardation ◽  
Uterine Fibroids ◽  
Reproductive Age ◽  
Premature Labor ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Abruptio Placentae ◽  
Intrauterine Growth ◽  
Peripartum Hemorrhage ◽  
Highly Correlated

Uterine fibroid is one of the most common intrauterine masses among females at the reproductive age. Pregnancy and uterine fibroids are highly correlated. Pregnancy-related hormones influence the size of uterine fibroids, and fibroids have many impacts on pregnancy. Although most if the uterine fibroids are asymptomatic during pregnancy, serious complications may occur. The main complications include abortion, premature rupture of membranes, premature labor, abruptio placentae, peripartum hemorrhage, fetal malpresentation, fetal intrauterine growth retardation, small for gestational age infants, and fetal anomalies. The main risk factors for complications are related to the fibroid number, size, volume, location, and type. Large, multiple, retroplacental, submucosal, subserosal, pedunculated, or low-lying fibroids carries the highest risk for complications during pregnancy. This review will address the prevalence of uterine fibroids during pregnancy, its effects, and complications.

Time-dependent changes in bone, placental, intestinal, and hepatic alkaline phosphatase activities in serum during human pregnancy.

1987 ◽  
Vol 33 (10) ◽  
pp. 1801-1806 ◽  
Author(s):  
G J Valenzuela ◽  
L A Munson ◽  
N M Tarbaux ◽  
J R Farley
Keyword(s):  
Alkaline Phosphatase ◽  
Pregnant Women ◽  
Bone Alkaline Phosphatase ◽  
Premature Labor ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Serum Samples ◽  
Lactating Women ◽  
Alp Activity ◽  
Duration Of Pregnancy

Abstract To measure changes in bone alkaline phosphatase (EC 3.1.3.1) activity in serum as a function of duration of pregnancy, we adapted our existing alkaline phosphatase (ALP) isoenzyme assay (which has been used to measure bone, hepatic, and intestinal ALP activities in serum, in the absence of placental ALP) to allow quantification of individual ALP isoenzyme activities in the presence of placental ALP. The resulting CV for repeat measurements of bone ALP activity in artificial isoenzyme mixtures ranged from 23% for samples in which the bone isoenzyme represented 7% of total ALP activity to 11% for samples in which bone ALP accounted for 48% of total ALP activity. Values for repeat determinations of bone ALP activity in human serum samples (i.e., including samples obtained from pregnant women and from nonpregnant controls) varied by an average of 18%. We find, in initial applications of this method, that (a) the amount of bone ALP activity in serum is increased during pregnancy (P less than .001), and remains increased at six weeks postpartum, in non-lactating women (P less than .001), and (b) bone ALP activity at term was not significantly different in pregnant women with pre-eclampsia, diabetes, premature rupture of membranes, or premature labor, compared with normal pregnancies at term. Our data support the hypothesis that maternal bone formation may be increased during pregnancy.

scholarly journals Pregnancy outcome in a bicornuate uterus with bilateral pregnancy presenting as threatened abortion: a case report

2021 ◽  
Vol 10 (11) ◽  
pp. 4334
Author(s):  
Tanaya Acharyya ◽  
Bandana Shyam Gohain ◽  
Kripanath Morang
Keyword(s):  
Case Report ◽  
Pregnancy Outcome ◽  
Premature Labor ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Mullerian Anomalies ◽  
Bicornuate Uterus ◽  
Spontaneous Conception ◽  
Uterine Anomalies ◽  
Threatened Abortion

Congenital uterine anomalies or mullerian anomalies are prevalent in 0.4 to 10% of women in general and are often manifested by reproductive challenges like miscarriage, premature labor, premature rupture of membranes or malpresentation. Having a bilateral pregnancy in a bicornuate uterus is extremely rare, especially if it is a spontaneous conception.

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