Dentin permeability, dentin sensitivity, and treatment through tubule occlusion

1986 ◽  
Vol 12 (10) ◽  
pp. 465-474 ◽  
Author(s):  
David H. Pashley
1997 ◽  
Vol 11 (4) ◽  
pp. 487-501 ◽  
Author(s):  
D.G. Gillam ◽  
N.J. Mordan ◽  
H.N. Newman

Dentin sensitivity (DS) is a painful clinical condition which may affect 8-35% of the population. Various treatment modalities have claimed success in relieving DS, although at present there does not appear to be a universally accepted desensitizing agent. Current opinion based on Brannstrom's Hydrodynamic Theory would suggest that following exposure of the dentin surface (through attrition, abrasion, or erosion), the presence of open dentinal tubules, patent to the pulp, may be a prerequisite for DS. The concept of tubule occlusion as a method of dentin desensitization, therefore, is a logical conclusion from the hydrodynamic theory. The fact that many of the agents used clinically to desensitize dentin are also effective in reducing dentin permeability tends to support the hydrodynamic theory. This paper reviews the in vitro evaluation of desensitizing agents, the techniques used to characterize their effects on the prepared dentin surface, and the ability of these agents to reduce permeability through tubule occlusion, and presents recent findings from ongoing research based on the Pashley Dentin Disc model. It can be concluded that the use of this model to determine surface characteristics, and reductions in dentin permeability through tubule narrowing or occlusion, provides a useful screening method for evaluating potential desensitizing agents. Interpreting changes observed in vitro is difficult, and extrapolation to the clinical situation must be tempered with caution.


2021 ◽  
Vol 71 (11) ◽  
pp. 2604-2610
Author(s):  
Hashmat Gul ◽  
Muhammad Asad Ghaffar ◽  
Muhammad Kaleem ◽  
Abdul Samad Khan

Objective: This study reviews different modes of application of hydroxyapatite for treatment of dentin hypersensitivity via dentinal tubule occlusion. Methods: Literature search was performed using keywords, “hydroxyapatite and dentin hypersensitivity, hydroxyapatite and dentinal tubule occlusion, hydroxyapatite and dentin permeability, dentinal tubule occlusion” on Pubmed, Science Direct and Web of Science, which involved the results of previous 10 years (2009-2018). After screening, 16 studies were included in systematic review. Results: The results of in-vitro studies showed that application of hydroxyapatite caused dentinal tubule occlusion leading to reduction in dentin permeability and reduction in dentin hypersensitivity. Conclusion: Hydroxyapatite has the potential to reduce dentin hypersensitivity via dentinal tubule occlusion within 2-8 weeks. Keywords: Dentin hypersensitivity, Hydroxyapatite, Dentinal tubule occlusion. Continuous...


2018 ◽  
Vol 19 (5) ◽  
pp. 285
Author(s):  
J S Nojosa ◽  
T A D Mendes ◽  
M V S Lemos ◽  
V P Feitosa ◽  
S L Santiago ◽  
...  

Objetivou-se avaliar fitocomplexos, como agentes de oclusão de dentina tubular, para o tratamento da hipersensibilidade dentinária. Dezesseis terceiros molares foram cortados transversalmente para obtenção de discos de dentina com espessura de 1 mm. Os espécimes foram divididos em 4 grupos (n4), de acordo com o tratamento: oxa-gel (Kota) (controle), extrato seco liofilizado de manjericão, hortelã e espinafre, na concentração de 5%. No teste de permeabilidade dentinária, os discos foram submetidos ao condicionamento com ácido fosfórico 37%, para medição da condutância hidráulica (Pmax). Após aplicação dos tratamentos por 5 minutos, mediu-se a condutância hidraúlica (Pmin). A resistência dos tratamentos ao desafio ácido foi avaliada após aplicação do ácido cítrico 7%, por 1 min. Para verificar a formação de oxalato de cálcio no FTIR, os discos foram tratados, conforme seu respectivo grupo, por 5 min. Na análise estatística, realizou-se o teste ANOVA um fator, seguido do pós-teste de Tukey (p≤0,05) para analisar a permeabilidade. Entre os tratamentos não houve diferença significante na permeabilidade dentinária (p0,683), porém quando todos tratamentos foram comparados, mostraram-se resistentes ao desafio ácido (p0,01). No FTIR realizou-se uma análise qualitativa, onde apenas o grupo hortelã não apresentou uma precipitação de oxalato considerável. Conclui-se que os fitocomplexos foram capazes de ocluir os túbulos dentinários e permitiram a deposição de oxalato de cálcio, sendo bastante promissores no tratamento da hipersensibilidade dentinária.Palavras-chave: Dentin Sensitivity. Dentin Permeability. Calcium Oxalate.


2019 ◽  
Vol 86 ◽  
pp. 53-59 ◽  
Author(s):  
Alana Cristina Machado ◽  
Fernanda Ellen Mercatelli Rabelo ◽  
Vinicius Maximiano ◽  
Raquel Marianna Lopes ◽  
Ana Cecilia Corrêa Aranha ◽  
...  

2017 ◽  
Vol 28 (2) ◽  
pp. 216-224 ◽  
Author(s):  
Gabriela D. Canali ◽  
Rodrigo N. Rached ◽  
Rui F. Mazur ◽  
Evelise M. Souza

The aim of the study was to evaluate dentinal tubule occlusion, measuring the dentin permeability (Lp) and using different desensitizing agents before and after abrasive/erosive challenge. Dentin discs from 42 healthy human third molars were obtained. Minimum Lp was measured after a smear layer simulation using #600 SiC paper and maximum Lp after an immersion in 0.5 M EDTA. The specimens were treated with different desensitizers: two varnishes (Clinpro XT Varnish-CV, Fluor Protector-FP), a paste (Desensibilize Nano P-NP) and a gel (Oxa Gel-OG). The Lp of each specimen was measured immediately after the desensitizers’ application. The discs were subjected to erosion/abrasion cycles for 7 days, with 0.5% citric acid solution (6x/day) and tooth brushing (3x/day). Lp was measured after the first, fourth and seventh day of the challenge. The data were analyzed by 3-way ANOVA with repeated measurements and by a Games-Howell test (α=5%). FP and CV did not show significant differences in Lp immediately after application until the 7th day (p<0.05). OG showed a significant increase in Lp after the 4th and 7th days. NP resulted in a significantly higher permeability compared to the other materials immediately after the application and after the 1st day of challenge. All the desensitizers reduced the dentin permeability immediately after application. However, only the varnishes were able to maintain the occlusive effect after the erosion/abrasion challenge.


2021 ◽  
Vol 29 ◽  
Author(s):  
Vinícius MAXIMIANO ◽  
Alana Cristina MACHADO ◽  
Raquel Marianna LOPES ◽  
Fernanda Ellen Mercatelli RABELO ◽  
Stephanie Assimakopoulos GARÓFALO ◽  
...  

2010 ◽  
Vol 52 (1) ◽  
pp. 23-32 ◽  
Author(s):  
Shelon Cristina S. Pinto ◽  
Márcia T. Pochapski ◽  
Denise S. Wambier ◽  
Gibson L. Pilatti ◽  
Fábio A. Santos

Author(s):  
Ruthinea Faria de Moraes Cardoso ◽  
Rosanna Tarkany Basting ◽  
Fabiana Mantovani Gomes França ◽  
Flávia Lucisano Botelho do Amaral ◽  
Roberta Tarkany Basting

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Yuko Shinno ◽  
Takuya Ishimoto ◽  
Mitsuru Saito ◽  
Reo Uemura ◽  
Masumi Arino ◽  
...  

1988 ◽  
Vol 4 (2) ◽  
pp. 60-63 ◽  
Author(s):  
D.H. Pashley ◽  
G.D. Derkson ◽  
L. Tao ◽  
M. Derkson ◽  
S. Kalathoor

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