SERUM-INSULIN IN ESSENTIAL HYPERTENSION AND IN PERIPHERAL VASCULAR DISEASE

The Lancet ◽  
1966 ◽  
Vol 287 (7451) ◽  
pp. 1336-1337 ◽  
Author(s):  
T.A. Welborn ◽  
A. Breckenridge ◽  
A.H. Rubinstein ◽  
C.T. Dollery ◽  
T.Russell Fraser
PEDIATRICS ◽  
1986 ◽  
Vol 78 (5) ◽  
pp. 956-957
Author(s):  
CHARLES J. GLUECK

In Reply.— Because the anatomic, biochemical, epidemiologic, nutritional, genetic, and clinical genesis of atherosclerosis is in childhood,1,2 it is important to consider models for sampling in childhood for the dyslipoproteinemias. At a minimum, I would recommend a family history-triggered high-risk strategy with sampling of all children whose parents had sustained premature (≤age 60 years) myocardial infarction, angina, cerebrovascular accident, or peripheral vascular disease.1,2 Second, all children with known parental dyslipoproteinemia should be sampled, as should all children with parental history of essential hypertension gout/hyperuricemia, and/or diabetes.


1982 ◽  
Vol 20 (9) ◽  
pp. 33-35

Indoramin (Baratol - Wyeth) has been recently introduced for the treatment of all grades of essential hypertension. The manufacturer claims that it causes arteriolar dilatation without a compensatory tachycardia and is without risk of exacerbating bronchospasm or the symptoms of peripheral vascular disease.


1982 ◽  
Vol 48 (03) ◽  
pp. 289-293 ◽  
Author(s):  
B A van Oost ◽  
B F E Veldhuyzen ◽  
H C van Houwelingen ◽  
A P M Timmermans ◽  
J J Sixma

SummaryPlatelets tests, acute phase reactants and serum lipids were measured in patients with diabetes mellitus and patients with peripheral vascular disease. Patients frequently had abnormal platelet tests and significantly increased acute phase reactants and serum lipids, compared to young healthy control subjects. These differences were compared with multidiscriminant analysis. Patients could be separated in part from the control subjects with variables derived from the measurement of acute phase proteins and serum lipids. Platelet test results improved the separation between diabetics and control subjects, but not between patients with peripheral vascular disease and control subjects. Diabetic patients with severe retinopathy frequently had evidence of platelet activation. They also had increased acute phase reactants and serum lipids compared to diabetics with absent or nonproliferative retinopathy. In patients with peripheral vascular disease, only the fibrinogen concentration was related to the degree of vessel damage by arteriography.


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