DOPPLER FLOW VELOCITY IN ANTERIOR CEREBRAL ARTERY FOR PREDICTION OF OUTCOME AFTER PERINATAL ASPHYXIA

The Lancet ◽  
1987 ◽  
Vol 329 (8532) ◽  
pp. 562 ◽  
Author(s):  
LyaDen Ouden ◽  
Frank Van Bel ◽  
Margot Van De Bor ◽  
Theo Stijnen ◽  
Jan Ruys ◽  
...  
Keyword(s):  
Flow Velocity ◽  
Cerebral Artery ◽  
Anterior Cerebral Artery ◽  
Perinatal Asphyxia ◽  
Prediction Of Outcome ◽  
Doppler Flow

scholarly journals Doppler Flow Velocity Indices (RI, PI, S/D & PSV) of Fetal Middle Cerebral Artery in Normal Pregnancies: Correlation with Gestational Age of 20 to 40 Weeks

2012 ◽  
Vol 2 (2) ◽  
pp. 77-80
Author(s):  
Md Abu Taher ◽  
Nuzhat Tasmin ◽  
AS Mohiuddin ◽  
Md Mohit Ul Alam ◽  
Md Mofazzal Sharif ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Flow Velocity ◽  
Cerebral Artery ◽  
Gestational Age ◽  
Resistance Index ◽  
Peak Systolic Velocity ◽  
Doppler Flow ◽  
Significant Difference ◽  
Before And After ◽  
Doppler Indices

This observational type of descriptive study was carried out in the Department of Radiology and Imaging, BIRDEM selecting 70 Bangladeshi pregnant babies with the aim to find out the normogram of foetal middle cerebral artery Doppler flow velocity indices and correlation between Doppler flow velocity indices [Resistance Index (RI), Pulsatility Index (PI), Systolic/Diastolic ratio (S/D) & Peak Systolic Velocity (PSV)] of foetal middle cerebral artery and gestational age in normal pregnancies of 20 to 40 weeks. It was observed that RI, PI and S/D were decreased with the advance of gestational age but PSV was increases with the advance of gestational age. Statistical analyses showed there were significant difference between mean PSV, RI and PI before and after 25 weeks of gestation. No significant difference was found between mean S/D before and after 25 weeks of gestation. It was observed from Correlation analysis between Doppler indices with independent gestational age that all the Doppler indices of foetal middle cerebra artery was positively correlated with the whole gestation period. The statistical analysis showed only PSV and RI were significantly correlated with the gestational age. Simple regression analysis between dependent Doppler index with independent gestational age before and after 25 weeks revealed that all the Doppler indices had positive relationship with the corresponding gestational age but relationship between PSV and PI (before 25 weeks) with their corresponding gestational ages were only statistically significant.DOI: http://dx.doi.org/10.3329/birdem.v2i2.12306 Birdem Med J 2012; 2(2) 77-80

Validity of Doppler Measurements of Anterior Cerebral Artery Blood Flow Velocity: Correlation with Brain Blood Flow in Piglets

PEDIATRICS ◽  
1983 ◽  
Vol 72 (4) ◽  
pp. 526-531
Author(s):  
Nancy B. Hansen ◽  
Barbara S. Stonestreet ◽  
Ted S. Rosenkrantz ◽  
William Oh
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
Continuous Wave ◽  
Anterior Cerebral Artery ◽  
Brain Blood Flow ◽  
Velocity Measurements ◽  
Doppler Flow ◽  
Continuous Wave Doppler

Continuous wave Doppler ultrasonography through the anterior fontanel has recently been used to assess changes in cerebral blood flow in human neonates. There has been controversy concerning whether measurements of Doppler blood flow velocity indeed correlate with brain blood flow. An in vivo correlation was performed between brain blood flow as measured by the microsphere method and Doppler flow velocity measurements of the cerebral arteries via an artificial fontanel in young piglets. The peak systolic velocity (r = .76, P < .001), end diastolic velocity (r = .72, P < .001) and area under the velocity curve (r = .86, P<.001) all showed significant positive correlations with brain blood flow. The pulsatility index did not correlate with brain blood flow. Although continuous wave Doppler flow velocity measurements of the anterior cerebral artery cannot quantitatively assess cerebral blood flow, this methodology can be used to correlate changes in cerebral blood flow and provide a meaningful trend analysis following physiologic or pharmacologic perturbation of the cerebral circulation.

scholarly journals Informativity of blood flow distribution in the precerebral arteries for determining the hemodynamic significance of carotid stenosis

2021 ◽  
Vol 20 (2) ◽  
pp. 45-51
Author(s):  
V. B. Semenyutin ◽  
А. А. Nikiforova ◽  
V. A. Aliev ◽  
G. К. Panuntsev
Keyword(s):  
Blood Flow ◽  
Carotid Artery ◽  
Flow Velocity ◽  
Carotid Stenosis ◽  
Cerebral Artery ◽  
Blood Flow Velocity ◽  
Anterior Cerebral Artery ◽  
Flow Distribution ◽  
External Carotid ◽  
Blood Flow Distribution

Introduction. Conventionally, hemodynamic significance of carotid stenosis is characterized with an increased peak systolic velocity up to 230 cm/s, which corresponds to 70 % carotid stenosis. This does not take into account changes of cerebral hemodynamics or collateral circulation, which can be determined by assessment of blood flow distribution in precerebral arteries. Aim – to evaluate blood flow redistribution in precerebral arteries in patients with critical carotid stenosis. Materials and methods. 40 patients (aged 49–80 y. o.) with critical carotid stenosis were studied (13 patients had 70–79 % stenosis, 11 patients – 80–89 %, and 16 patients – 90–99 % stenosis). Flow velocity index in precerebral arteries was determined with duplex scanning (Vivid e, USA), whereas linear blood flow velocity in intracranial arteries – with transcranial Doppler (MultiDop X, Germany). Results. In 60 % of patients, flow velocity index in ipsilateral carotid artery was reliably decreased (p<0.05). In 49 % of patients flow velocity index in contralateral carotid artery and blood flow velocity in contralateral anterior cerebral artery were reliably increased (p<0.05), as well as linear blood flow velocity in the contralateral anterior cerebral artery. Just in 39 % of patients flow velocity index in ipsilateral vertebral artery and linear blood flow velocity in ipsilateral posterior cerebral artery were increased (p<0.05). In 13 % of cases flow velocity index in the external carotid artery was increased (p<0.05). Conclusion. Thus, critical degree of carotid stenosis does not always indicate its hemodynamic significance. Flow velocity index distribution in precerebral arteries can be used as an additional criterion for assessing hemodynamic significance of carotid stenosis and, along with other indicators, should be taken into account when choosing treatment modality.

Resistive Index in Late-Onset Neonatal Sepsis

2018 ◽  
Vol 32 (4) ◽  
pp. 93-97
Author(s):  
Rameshwor Yengkhom ◽  
Pradeep Suryawanshi ◽  
Snehal Ingale ◽  
Bhvya Gupta ◽  
Sujata Deshpande
Keyword(s):  
Cerebral Artery ◽  
Neonatal Sepsis ◽  
Anterior Cerebral Artery ◽  
Late Onset ◽  
Perinatal Asphyxia ◽  
Newborn Infants ◽  
Resistive Index ◽  
Genetic Syndromes ◽  
Hemodynamic State ◽  
The Mean

Background and Objectives: Hemodynamics in neonatal sepsis is complex and poorly understood. Several studies have reported conflicting findings on cerebral blood flow (CBF) in sepsis from severely increased flow to severely decreased flow. The objective of our study was to study CBF by measuring the resistive index (RI) of the anterior cerebral artery in late-onset neonatal sepsis (LONS). Methods: All newborn infants admitted in our neonatal intensive care unit with suspected LONS during the period from January 2017 to December 2017 underwent point-of-care transcranial Doppler ultrasonography to measure the RI of the anterior cerebral artery within 24 h of clinical presentation before starting inotropes if at all required. Infants with congenital heart disease, perinatal asphyxia, major congenital malformations, and genetic syndromes were excluded. Neonates with positive culture were included in the final analysis. Results: Of 89 suspected LONS, 33 were culture positive and were analyzed. The mean admission weight was 2.33 ± 0.76 kg. The mean gestational age was 33.5 ± 3.4 wk. Most common organism isolated was Klebsiella pneumoniae (82%). The RI was high in 54.5% (17 of 33) and normal in 45.5% (15 of 33) cases. Conclusions: LONS is a unique and complex hemodynamic state and we found it associated with the high RI indicating decreased CBF. A larger study may help in more understanding of this unique hemodynamic association.

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