Effects of substrate feed rates on heterologous protein expression by Pichia pastoris in DO-stat fed-batch fermentation

Fed Batch ◽

Translational Arrest Due to Cytoplasmic Redox Stress Delays Adaptation to Growth on Methanol and Heterologous Protein Expression in a Typical Fed-Batch Culture of Pichia pastoris

PLoS ONE ◽

10.1371/journal.pone.0119637 ◽

2015 ◽

Vol 10 (3) ◽

pp. e0119637 ◽

Cited By ~ 10

Author(s):

Bryn Edwards-Jones ◽

Rochelle Aw ◽

Geraint R. Barton ◽

Gregory D. Tredwell ◽

Jacob G. Bundy ◽

...

Keyword(s):

Pichia Pastoris ◽

Protein Expression ◽

Batch Culture ◽

Heterologous Protein ◽

Fed Batch ◽

Redox Stress ◽

Translational Arrest ◽

Fed Batch Culture

Overexpression of the regulatory subunit of protein kinase A increases heterologous protein expression in Pichia pastoris

Biotechnology Letters ◽

10.1007/s10529-020-02977-z ◽

2020 ◽

Vol 42 (12) ◽

pp. 2685-2692 ◽

Cited By ~ 1

Author(s):

Xihao Liao ◽

Wenyang Lin ◽

Nanzhu Chen ◽

Lu Li ◽

Dafu Huang ◽

...

Keyword(s):

Protein Kinase ◽

Pichia Pastoris ◽

Protein Expression ◽

Protein Kinase A ◽

Heterologous Protein ◽

Regulatory Subunit ◽

Kinase A

Author response for "Holistic process development to mitigate proteolysis of a subunit rotavirus vaccine candidate produced in Pichia pastoris by means of an acid pH pulse during fed‐batch fermentation"

10.1002/btpr.2966/v2/response1 ◽

2020 ◽

Author(s):

M. Lourdes Velez‐Suberbie ◽

Stephen A. Morris ◽

Kawaljit Kaur ◽

John M. Hickey ◽

Sangeeta B. Joshi ◽

...

Keyword(s):

Pichia Pastoris ◽

Batch Fermentation ◽

Process Development ◽

Vaccine Candidate ◽

Author Response ◽

Rotavirus Vaccine ◽

Fed Batch ◽

Holistic Process ◽

Fed Batch Fermentation ◽

A Subunit

Enhancing the Production of Fc Fusion Protein in Fed-Batch Fermentation of Pichia pastoris by Design of Experiments

Biotechnology Progress ◽

10.1021/bp0603199 ◽

2008 ◽

Vol 23 (3) ◽

pp. 621-625 ◽

Cited By ~ 20

Author(s):

Henry Lin ◽

Tina Kim ◽

Fei Xiong ◽

Xiaoming Yang

Keyword(s):

Pichia Pastoris ◽

Fusion Protein ◽

Design Of Experiments ◽

Batch Fermentation ◽

Fed Batch ◽

Fc Fusion Protein ◽

Large-Scale Production of Glaciozyma antarctica Antifreeze Protein 1 (Afp1) by Fed-Batch Fermentation of Pichia pastoris

Arabian Journal for Science and Engineering ◽

10.1007/s13369-017-2738-1 ◽

2017 ◽

Vol 43 (1) ◽

pp. 133-141 ◽

Cited By ~ 2

Author(s):

Mahzan Md Tab ◽

Noor Haza Fazlin Hashim ◽

Nazalan Najimudin ◽

Nor Muhammad Mahadi ◽

Farah Diba Abu Bakar ◽

...

Keyword(s):

Pichia Pastoris ◽

Batch Fermentation ◽

Large Scale ◽

Antifreeze Protein ◽

Scale Production ◽

Fed Batch ◽

Large Scale Production ◽

Coupling aerobic biodegradation of methanol vapors with heterologous protein expression of endochitinase Ech42 from Trichoderma atroviride in Pichia pastoris

Bioresource Technology ◽

10.1016/j.biortech.2010.06.092 ◽

2010 ◽

Vol 101 (24) ◽

pp. 9661-9665 ◽

Cited By ~ 8

Author(s):

Sonia Arriaga ◽

Julia A. Acosta-Munguía ◽

Ana S. Pérez-Martínez ◽

Antonio De León-Rodríguez ◽

Ana P. Barba de la Rosa

Keyword(s):

Pichia Pastoris ◽

Protein Expression ◽

Heterologous Protein ◽

Aerobic Biodegradation ◽

Trichoderma Atroviride

Maximization of Production of Secreted Recombinant Proteins in Pichia pastoris Fed-Batch Fermentation

Biotechnology Progress ◽

10.1021/bp049811n ◽

2008 ◽

Vol 21 (2) ◽

pp. 386-393 ◽

Cited By ~ 39

Author(s):

Wenhui Zhang ◽

Jayanta Sinha ◽

Leonard A. Smith ◽

Mehmet Inan ◽

Michael M. Meagher

Keyword(s):

Pichia Pastoris ◽

Recombinant Proteins ◽

Batch Fermentation ◽

Fed Batch ◽

Review for "Holistic process development to mitigate proteolysis of a subunit rotavirus vaccine candidate produced in Pichia pastoris by means of an acid pH pulse during fed‐batch fermentation"

10.1002/btpr.2966/v1/review1 ◽

2019 ◽

Keyword(s):

Pichia Pastoris ◽

Batch Fermentation ◽

Process Development ◽

Vaccine Candidate ◽

Rotavirus Vaccine ◽

Fed Batch ◽

Acid Ph ◽

Holistic Process ◽

Fed Batch Fermentation ◽

A Subunit

Incomplete protein disulphide bond conformation and decreased protein expression result from high cell growth during heterologous protein expression in Pichia pastoris

Journal of Biotechnology ◽

10.1016/j.jbiotec.2011.08.032 ◽

2012 ◽

Vol 157 (1) ◽

pp. 107-112 ◽

Cited By ~ 6

Author(s):

Dan Wu ◽

Ju Chu ◽

Yu-You Hao ◽

Yong-Hong Wang ◽

Ying-Ping Zhuang ◽

...

Keyword(s):

Cell Growth ◽

Pichia Pastoris ◽

Protein Expression ◽

Heterologous Protein ◽

Disulphide Bond ◽

High Cell

Continuous operation, a realistic alternative to fed-batch fermentation for the production of recombinant lipase B from Candida antarctica under the constitutive promoter PGK in Pichia pastoris

Biochemical Engineering Journal ◽

10.1016/j.bej.2019.03.027 ◽

2019 ◽

Vol 147 ◽

pp. 39-47 ◽

Cited By ~ 4

Author(s):

Julia de Macedo Robert ◽

Xavier Garcia-Ortega ◽

José Luis Montesinos-Seguí ◽

Denise Maria Guimaraes Freire ◽

Francisco Valero

Keyword(s):

Pichia Pastoris ◽

Batch Fermentation ◽

Candida Antarctica ◽

Continuous Operation ◽

Constitutive Promoter ◽

Fed Batch ◽

Lipase B ◽

Recombinant Lipase ◽