49 The relationship of family history of hypertension and psychological traits to myocardial, vascular and dual hemodynamic reactivity patterns

1998 ◽  
Vol 30 (1-2) ◽  
pp. 21-22
Author(s):  
K.A. Lawler ◽  
J.S. Krishnamoorthy ◽  
I. Edgemon ◽  
J.E. Lawler
SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A248-A248
Author(s):  
Kristi Porterfield-Pruss ◽  
Denise Willis ◽  
Beverly Spray ◽  
Supriya Jambhekar

Abstract Introduction Limited evidence suggests a familial association of OSA. It is not known how often children who require positive airway pressure (PAP) devices have a family member with OSA or that requires PAP. It is felt that PAP adherence in children is affected by PAP adherence in parents. We wanted to explore the relationship of OSA in children requiring PAP to OSA in immediate family members as well as the association of obesity and adherence between children and family members. Methods Caregivers of children who utilize PAP devices at home were invited to complete an electronic questionnaire regarding family history of OSA. Descriptive statistics were utilized to summarize results. Results The study was completed by 75 participants. The majority of children were male (64%, 48/75), black (47%, 35/75) and non-Hispanic (88%, 66/75). The mean age was 11.8 years (median 13) and mean BMI was 32.8 (median 29.8). The mean AHI on the diagnostic polysomnogram was 28.4 events per hour (median 15.3). Mean adherence to PAP > 4 hours per night was 56.5 (Median 68.2). Most, 87% (65/75), have other underlying medical problems. Twenty-four percent (18/75) have a biological father with OSA of whom 61% (11/18) are considered moderately/extremely obese. Of mothers, 13% (10/75) have OSA and 70% (7/10) are obese. Overall, 29% (22/75) had either a paternal (11%, 8/75) or maternal (19%, 14/75) grandfather with OSA of which 36% (8/22) are obese. For grandmothers, 31% (23/75) have OSA and 22% (5/23) are obese with more being paternal (19%, 14/75) compared to maternal (12%, 9/75). Of the 73 total family members reported to have OSA, 86% (63/73) use PAP and most (65%, 41/63) use it for > 4 hours every night. Few participants had siblings with OSA. Conclusion There were more fathers with OSA than mothers, but mothers were reported to be obese more often. Grandparents were reported to have OSA but were reported to be obese less often than parents. Maternal grandparents with OSA were reported to be obese more than paternal grandparents. The majority of family members with OSA who use CPAP report nightly use. Support (if any):


2001 ◽  
Vol 35 (2) ◽  
pp. 217-223 ◽  
Author(s):  
Ross M. G. Norman ◽  
Ashok K. Malla

Objective: It has been hypothesized that patients with a diagnosis of schizophrenia who have a positive family history for schizophrenia will show greater reactivity of their symptoms to increasing levels of stress or negative affect than will patients without such a family history. In the past this hypothesis has only been tested through manipulations of negative affect in laboratory settings. In this paper we test this hypothesis using longitudinal clinical data. Method: Data were derived from an earlier longitudinal study using monthly assessments of daily stressors (Hassles Scale) and symptom measures (the Scale for the Assessment of Positive Symptoms and the Scale for the Assessment of Negative Symptoms). We compared longitudinal stress to symptom relations in 12 patients with schizophrenia for whom a positive family history of schizophrenia could be identified with 12 matched schizophrenic patients without any known family history of psychiatric illness. Results: There was evidence that patients with a family history of schizophrenia demonstrated a stronger relation between stress and total score on the Scale for the Assessment of Positive Symptoms. This difference appears to have primarily reflected a greater reactivity to stress of reality distortion symptoms in the positive family history group. The two groups did not differ in apparent reactivity to stress of the disorganization and psychomotor poverty dimensions of symptomatology. Conclusions: The results of this study provide support from a naturalistic, longitudinal clinical study for the hypothesis that reactivity to stress of some symptoms of schizophrenia may vary as a function of family history of the disorder.


1993 ◽  
Vol 55 (1) ◽  
pp. 70-77 ◽  
Author(s):  
F A Treiber ◽  
F McCaffrey ◽  
L Musante ◽  
T Rhodes ◽  
H Davis ◽  
...  

1983 ◽  
Vol 143 (2) ◽  
pp. 133-138 ◽  
Author(s):  
K. O'Sullivan ◽  
P. Whillans ◽  
M. Daly ◽  
B. Carroll ◽  
A. Clare ◽  
...  

SummaryThree hundred male Irish alcoholics were selected from 508 consecutive alcoholic admissions to hospital. Using well defined diagnostic criteria, they were divided into three subgroups (1) primary alcoholics, (2) alcoholics with secondary affective disorder and (3) those with primary affective disorder and secondary alcoholism. Although the three groups reported differences in past history and family history of affective disorder and in time spent in hospital for both alcoholism and affective disorder, there was little to distinguish them in behaviour associated with alcoholism or in family history of alcoholism. The implications of these findings and their significance for the relationship of affective disorder and alcoholism are discussed.


1979 ◽  
Vol 1 (2) ◽  
pp. 105-113 ◽  
Author(s):  
Bruce Hensel ◽  
David L. Dunner ◽  
Ronald R. Fieve

2020 ◽  
Author(s):  
Dwi Ayu Lestari ◽  
Ichsan Trisutrino ◽  
Kustia Anggereni ◽  
Resita Nurbayani

Hypertension is a non-communicable disease which causes death in the world, including in Indonesia. Increased prevalence of hypertension can be caused by lifestyle, stress and others. The purpose of this study was to determine the relationship between the incidence of hypertension and family history of suffering from hypertension. This study used an analytical survey with aCross-Sectional Study design conducted in August 2019. The research instrument was a questionnaire and blood pressure measurement. A total of 177 Summarecon Mall Serpong visitors were respondents in the study taken by accidental sampling. Data analysis using Chi Square test. The results of this study indicate that respondents who suffer from hypertension with a family history of hypertension by 60% and respondents who do not suffer from hypertension 17.5%, the incidence of hypertension with a family history of hypertension namely (OR = 7.05; 95%; CI 3.54 -14.05; p-value = 0,000). People who have a family history of suffering from hypertension 7x more at risk of developing hypertension. The conclusion of this study is that there is a relationship between the incidence of hypertension with a family history of hypertension in Summarecon Mall Serpong Visitors


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