1222 Immunohistochemical analysis of developmental stage of apoptotic granule neurons in neonatal rat cerebellum

1997 ◽  
Vol 28 ◽  
pp. S155
Author(s):  
Masahiko Tanaka ◽  
Tohru Marunouchi
1974 ◽  
Vol 16 (3) ◽  
pp. 205-211 ◽  
Author(s):  
SETSUYA FUJITA ◽  
TAKANORI HATTORI ◽  
MASARU FUKUDA ◽  
TADAHISA KITAMURA

1982 ◽  
Vol 3 (4) ◽  
pp. 509-527 ◽  
Author(s):  
Shinobu Inagaki ◽  
Sadao Shiosaka ◽  
Kenichi Takatsuki ◽  
Hisashi Iida ◽  
Masahiro Sakanaka ◽  
...  

2003 ◽  
Vol 284 (4) ◽  
pp. R1138-R1146 ◽  
Author(s):  
Jing He ◽  
M. Thamotharan ◽  
Sherin U. Devaskar

We examined the effect of insulin on fetal/neonatal rat skeletal muscle GLUT-1 and GLUT-4 concentrations and subcellular distribution by employing immunohistochemical analysis and subcellular fractionation followed by Western blot analysis. We observed that insulin did not alter total GLUT-1 or GLUT-4 concentrations or the GLUT-1 subcellular distribution in fetal/neonatal or adult skeletal muscle in 60 min. The basal and insulin-induced changes in subcellular distribution of GLUT-4 were different between the fetal/neonatal and adult skeletal muscle. Under basal conditions, sarcolemma-associated GLUT-4 was higher in the newborn compared with the adult, translating into a higher glucose transport. In contrast, insulin-induced translocation of GLUT-4 to the sarcolemma- and insulin-induced glucose transport was lower in the newborn compared with the adult. This age-related change results in enhanced basal glucose transport to fuel myocytic proliferation and differentiation while relatively curbing the insulin-dependent glucose transport in the newborn.


2014 ◽  
Vol 8 (2) ◽  
pp. 121-124
Author(s):  
E. V. Stelmashook ◽  
S. V. Novikova ◽  
G. A. Amelkina ◽  
E. E. Genrikhs ◽  
L. G. Khaspekov ◽  
...  

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