69 Nuclear receptor (PXR, CAR) agonists induce adaptive hepatic transporter and enzyme expression in mouse liver

Journal of Hepatology ◽

10.1016/s0168-8278(04)90069-4 ◽

2004 ◽

Vol 40 ◽

pp. 25

Author(s):

M. Wagner ◽

E. Halibasic ◽

P. Fickert ◽

G. Zollner ◽

A. Fuchsbichler ◽

...

Keyword(s):

Nuclear Receptor ◽

Mouse Liver ◽

Enzyme Expression ◽

Hepatic Transporter

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Nuclear receptor co-repressor RIP140 regulates diurnal expression of cytochrome P450 2b10 in mouse liver

Xenobiotica ◽

10.1080/00498254.2020.1751342 ◽

2020 ◽

Vol 50 (10) ◽

pp. 1139-1148 ◽

Author(s):

Mengjing Zhao ◽

Huan Zhao ◽

Luomin Lin ◽

Yi Wang ◽

Menglin Chen ◽

...

Keyword(s):

Cytochrome P450 ◽

Nuclear Receptor ◽

Mouse Liver ◽

Diurnal Expression

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Hepatic Transporter Alterations by Nuclear Receptor Agonist T0901317 in Sandwich-Cultured Human Hepatocytes: Proteomic Analysis and PBPK Modeling to Evaluate Drug-Drug Interaction Risk

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.119.263459 ◽

2020 ◽

Vol 373 (2) ◽

pp. 261-268

Author(s):

Katsuaki Ito ◽

Noora Sjöstedt ◽

Melina M. Malinen ◽

Cen Guo ◽

Kim L.R. Brouwer

Keyword(s):

Drug Interaction ◽

Nuclear Receptor ◽

Proteomic Analysis ◽

Receptor Agonist ◽

Human Hepatocytes ◽

Pbpk Modeling ◽

Hepatic Transporter ◽

Drug Drug Interaction

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Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response

Biochemical and Biophysical Research Communications ◽

10.1016/s0006-291x(02)00196-1 ◽

2002 ◽

Vol 293 (1) ◽

pp. 145-149 ◽

Author(s):

Anne P Beigneux ◽

Arthur H Moser ◽

Judy K Shigenaga ◽

Carl Grunfeld ◽

Kenneth R Feingold

Keyword(s):

Acute Phase ◽

Acute Phase Response ◽

Mouse Liver ◽

Constitutive Androstane Receptor ◽

Pregnane X Receptor ◽

Phase Response ◽

Enzyme Expression ◽

Cytochrome P 450

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The Nuclear Receptor Constitutively Active/Androstane Receptor Regulates Type 1 Deiodinase and Thyroid Hormone Activity in the Regenerating Mouse Liver

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.106.112706 ◽

2006 ◽

Vol 320 (1) ◽

pp. 307-313 ◽

Author(s):

Eric S. Tien ◽

Kenji Matsui ◽

Rick Moore ◽

Masahiko Negishi

Keyword(s):

Thyroid Hormone ◽

Nuclear Receptor ◽

Mouse Liver ◽

Hormone Activity ◽

Constitutively Active

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Faculty Opinions recommendation of Critical illness evokes elevated circulating bile acids related to altered hepatic transporter and nuclear receptor expression.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13972976.15429083 ◽

2012 ◽

Author(s):

Michael Bauer

Keyword(s):

Critical Illness ◽

Nuclear Receptor ◽

Receptor Expression ◽

Hepatic Transporter

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Localization of the nuclear receptor CAR at the cell membrane of mouse liver

FEBS Letters ◽

10.1016/j.febslet.2005.10.070 ◽

2005 ◽

Vol 579 (30) ◽

pp. 6733-6736 ◽

Author(s):

Chika Koike ◽

Rick Moore ◽

Masahiko Negishi

Keyword(s):

Cell Membrane ◽

Nuclear Receptor ◽

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NUCLEAR RECEPTOR, PREGNANE X RECEPTOR, IS REQUIRED FOR INDUCTION OF UDP-GLUCURONOSYLTRANSFERASES IN MOUSE LIVER BY PREGNENOLONE-16α-CARBONITRILE

Drug Metabolism and Disposition ◽

10.1124/dmd.31.7.908 ◽

2003 ◽

Vol 31 (7) ◽

pp. 908-915 ◽

Author(s):

Chuan Chen ◽

Jeff L. Staudinger ◽

Curtis D. Klaassen

Keyword(s):

Nuclear Receptor ◽

Mouse Liver ◽

Pregnane X Receptor

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Correction: Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium

PLoS ONE ◽

10.1371/journal.pone.0124224 ◽

2015 ◽

Vol 10 (4) ◽

pp. e0124224 ◽

Author(s):

Keyword(s):

Gene Expression ◽

Nuclear Receptor ◽

Mouse Liver ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

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Overexpression of the Rho-guanine nucleotide exchange factor ECT2 inhibits nuclear translocation of nuclear receptor CAR in the mouse liver

FEBS Letters ◽

10.1016/j.febslet.2007.09.024 ◽

2007 ◽

Vol 581 (25) ◽

pp. 4937-4942 ◽

Author(s):

Fardin Hosseinpour ◽

Yoav Timsit ◽

Chika Koike ◽

Kenji Matsui ◽

Yukio Yamamoto ◽

...

Keyword(s):

Nuclear Receptor ◽

Mouse Liver ◽

Nuclear Translocation ◽

Guanine Nucleotide Exchange Factor ◽

Guanine Nucleotide ◽

Nucleotide Exchange ◽

Exchange Factor ◽

Guanine Nucleotide Exchange ◽

Nucleotide Exchange Factor

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Nuclear receptor CAR-regulated expression of the FAM84A gene during the development of mouse liver tumors

International Journal of Oncology ◽

10.3892/ijo.2011.980 ◽

2011 ◽

Author(s):

Masahiko Negishi

Keyword(s):

Nuclear Receptor ◽

Mouse Liver ◽

Liver Tumors ◽

Regulated Expression

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