scholarly journals 346 INCREASED LIVER EXPRESSION OF INFLAMMATORY MEDIATORS IS ASSOCIATED WITH HEPATIC INSULIN RESISTANCE IN LEAN, NON-DIABETIC PATIENTS WITH CHRONIC HEPATITIS C

2009 ◽  
Vol 50 ◽  
pp. S133
Author(s):  
E. Vanni ◽  
M.L. Abate ◽  
E. Gentilcore ◽  
C. Elia ◽  
R. Gambino ◽  
...  
2012 ◽  
Vol 29 (1) ◽  
Author(s):  
Zareen Kiran ◽  
Bader Faiyaz Zuberi ◽  
Daniah Anis ◽  
Rashid Qadeer ◽  
Khalid Hasan ◽  
...  

2011 ◽  
Vol 55 (6) ◽  
pp. 412-418 ◽  
Author(s):  
Aécio Flávio Meirelles de Souza ◽  
Fábio Heleno de Lima Pace ◽  
Júlio Maria Fonseca Chebli ◽  
Lincoln Eduardo Villela Vieira de Castro Ferreira

OBJECTIVES: To determine the prevalence of insulin resistance (IR) in non-diabetic patients with chronic hepatitis C, and to assess the association between IR, laboratory parameters and histological findings. SUBJECTS AND METHODS: Eighty-two patients had their serum analyzed for glucose, lipid profile, C-reactive protein (CRP), ferritin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), HOMA-IR, viral load and HCV genotype. Patients with HOMA-IR levels > 2.5 were considered as carriers of insulin resistance. RESULTS: IR was observed in 27% of patients and was associated with age, waist circumference and body mass index. IR patients were more likely to have more advanced hepatic fibrosis and necroinflammatory activity, higher levels of aminotransferases and liver steatosis than patients without IR. CONCLUSIONS: Insulin resistance is often present in patients with chronic hepatitis C, and this parameter is associated with more advanced HCV-related hepatic fibrosis.


2010 ◽  
Vol 138 (3) ◽  
pp. 932-941.e3 ◽  
Author(s):  
Kerry–Lee Milner ◽  
David van der Poorten ◽  
Michael Trenell ◽  
Arthur B. Jenkins ◽  
Aimin Xu ◽  
...  

2012 ◽  
Vol 33 (3) ◽  
pp. 410-419 ◽  
Author(s):  
Venessa Pattullo ◽  
Andres Duarte-Rojo ◽  
Wael Soliman ◽  
Florencia Vargas-Vorackova ◽  
Sanjeev Sockalingam ◽  
...  

2011 ◽  
Vol 54 (1) ◽  
pp. 142-152 ◽  
Author(s):  
Carmelo García-Monzón ◽  
Oreste Lo Iacono ◽  
Rafael Mayoral ◽  
Águeda González-Rodríguez ◽  
María E. Miquilena-Colina ◽  
...  

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