Value of Transient Elastography (Fibroscan®) in Patients with Autoimmune Hepatitis on Immunosuppressive Treatment

We report a case of a 25-year-old female patient who showed chronic hepatopathy with elevated levels of autoantibodies and gamma globulins, resembling autoimmune hepatitis. After 8 weeks of unsuccessful immunosuppressive treatment, further evaluation showed laboratorial and histological findings suggestive of Wilson’s disease. The new treatment with D-penicillamine resulted in positive outcome, despite the initial misleading diagnosis.

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Immunosuppressive Treatment Regimens in Autoimmune Hepatitis: Systematic Reviews and Meta‐Analyses Supporting American Association for the Study of Liver Diseases Guidelines

Hepatology ◽

10.1002/hep.31407 ◽

2020 ◽

Vol 72 (2) ◽

pp. 753-769 ◽

Cited By ~ 1

Author(s):

John M. Vierling ◽

Nanda Kerkar ◽

Albert J. Czaja ◽

Cara L. Mack ◽

David Adams ◽

...

Keyword(s):

Autoimmune Hepatitis ◽

Systematic Reviews ◽

Liver Diseases ◽

American Association ◽

Immunosuppressive Treatment ◽

Treatment Regimens ◽

Meta Analyses

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PTH-101 Accuracy of Transient Elastography in Predicting Histological Fibrosis Severity in Treated Autoimmune Hepatitis?: Abstract PTH-101 Table 1

Gut ◽

10.1136/gutjnl-2016-312388.505 ◽

2016 ◽

Vol 65 (Suppl 1) ◽

pp. A268-A269

Author(s):

L Harrison ◽

E McFarlane ◽

A Dube ◽

D Gleeson

Keyword(s):

Autoimmune Hepatitis ◽

Transient Elastography

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Transient elastography in patients with chronic autoimmune hepatitis: is a good tool in evaluation of hepatic fibrosis?

Digestive and Liver Disease ◽

10.1016/j.dld.2015.01.139 ◽

2015 ◽

Vol 47 ◽

pp. e64

Author(s):

S. Onali ◽

S. Cappellini ◽

G. Serra ◽

T. Zolfino ◽

D. Murgia ◽

...

Keyword(s):

Autoimmune Hepatitis ◽

Hepatic Fibrosis ◽

Transient Elastography ◽

Good Tool

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Complete regression of cirrhosis after immunosuppressive treatment in autoimmune hepatitis

Pediatrics International ◽

10.1111/j.1442-200x.2008.02714.x ◽

2008 ◽

Vol 50 (5) ◽

pp. 711-713 ◽

Cited By ~ 6

Author(s):

Gonca Ustundag ◽

Zarife Kuloglu ◽

Ceyda Tuna Kırsaçlıoğlu ◽

Aydan Kansu ◽

Esra Erden ◽

...

Keyword(s):

Autoimmune Hepatitis ◽

Immunosuppressive Treatment ◽

Complete Regression

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Pancolitis with Ischemic Injury as a Complication of Immunosuppressive Treatment in a Patient with Autoimmune Hepatitis: A Case Report

Case Reports in Gastrointestinal Medicine ◽

10.1155/2012/698404 ◽

2012 ◽

Vol 2012 ◽

pp. 1-3 ◽

Cited By ~ 1

Author(s):

A. Dalbeni ◽

E. Capoferro ◽

L. Bernardoni ◽

P. Capelli ◽

A. Caliò ◽

...

Keyword(s):

Autoimmune Hepatitis ◽

Ischemic Colitis ◽

Hepatitis A ◽

Immunosuppressive Treatment ◽

Ischemic Injury ◽

Entire Colon ◽

Drug Induced ◽

First Case ◽

Inflammatory Bowel ◽

Massive Rectal Bleeding

Ischemic colitis is a serious drug-induced adverse event. There are only few cases of immunosuppression-associated ischemic colitis described in the literature, but none with a pancolitis-like manifestation. We report the case of a 72-year-old female patient who developed a pancolitis with ischemic injury on immunosuppressive treatment with steroids and azathioprine for autoimmune hepatitis. The patient presented with massive rectal bleeding. Colonoscopy confirmed the diagnosis of pancolitis. The results of histological examination indicated drug-induced ischemic colitis involving the entire colon. This is the first case of ischemic pancolitis mimicking an inflammatory bowel disease (IBD) in a patient with immunosuppressive therapy.

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