Modulation of IL-1β, IL-6 and TNF-α Secretion and mRNA Expression by the Trichothecene Vomitoxin in the RAW 264.7 Murine Macrophage Cell Line

1998 ◽  
Vol 36 (5) ◽  
pp. 409-419 ◽  
Author(s):  
S.-S. Wong ◽  
H.-R. Zhou ◽  
M.L. Marin-Martinez ◽  
K. Brooks ◽  
J.J. Pestka
Shock ◽  
1997 ◽  
Vol 7 (Supplement) ◽  
pp. 92
Author(s):  
David Williams ◽  
Tuanzhu Ha ◽  
Chuanfu Li ◽  
Antje Müller ◽  
John Raptis ◽  
...  

BioTechniques ◽  
1999 ◽  
Vol 27 (4) ◽  
pp. 824-832 ◽  
Author(s):  
C.D. Thompson ◽  
M.R. Frazier-Jessen ◽  
R. Rawat ◽  
R.P. Nordan ◽  
R.T. Brown

2002 ◽  
Vol 25 (6) ◽  
pp. 895-902 ◽  
Author(s):  
Shinha Han ◽  
Ki -Hyun Sung ◽  
Dongsool Yim ◽  
Sookyeon Lee ◽  
Kyunghae Cho ◽  
...  

2000 ◽  
Vol 28 (02) ◽  
pp. 217-226 ◽  
Author(s):  
Hiroshi Kawamata ◽  
Hiroshi Ochiai ◽  
Naoki Mantani ◽  
Katsutoshi Terasawa

We have investigated the effect of Juzen-taiho-to (TJ-48) on inducible NO synthase (iNOS) expression and nitric oxide (NO) production in RAW264.7 cells, a murine macrophage cell line. TJ-48-lipopolysaccharide (LPS) combination induced iNOS mRNA expression earlier, stronger and remained longer that paralleled but with a higher NO production compared to LPS stimulation. TJ-48 itself showed no inducible effect either no NO production or iNOS mRNA expression. This phenomenon could be considered to contribute, at least in part, to the beneficial effects of TJ-48 through the iNOS-mediated activation of biodefense mechanism.


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