Cerebral cortical blood flow during loss of consciousness induced by gravitational stress in rhesus monkeys

2001 ◽  
Vol 305 (2) ◽  
pp. 99-102 ◽  
Author(s):  
Geneviève Florence ◽  
Richard Bonnier ◽  
Laurent Riondet ◽  
Didier Plagnes ◽  
Didier Lagarde ◽  
...  
Keyword(s):  
Blood Flow ◽  
Rhesus Monkeys ◽  
Loss Of Consciousness ◽  
Cortical Blood Flow ◽  
Gravitational Stress ◽  
Cerebral Cortical Blood Flow

Postnatal developmental changes in blood flow to choroid plexuses and cerebral cortex of the rat

1994 ◽  
Vol 266 (5) ◽  
pp. R1488-R1492
Author(s):  
J. Szmydynger-Chodobska ◽  
A. Chodobski ◽  
C. E. Johanson
Keyword(s):  
Blood Flow ◽  
Cerebral Cortex ◽  
Vascular System ◽  
Developmental Changes ◽  
Choroidal Blood Flow ◽  
Flow Rates ◽  
Cortical Blood Flow ◽  
Choroid Plexuses ◽  
Choroidal Epithelium ◽  
Cerebral Cortical Blood Flow

Postnatal developmental changes in blood flow to choroid plexuses of the lateral (LVCP) and fourth (4VCP) ventricles and cerebral cortex were studied in pentobarbital-anesthetized rats at 2, 3, 5, and 7-8 wk. Blood flow was measured by indicator fractionation with N-isopropyl-p-[125I]iodoamphetamine as the marker. Blood flow to the LVCP and 4VCP was 2.5 +/- 0.1 and 2.7 +/- 0.1 ml.g-1.min-1, respectively, and did not change between the 2nd and 3rd wk. However, it increased by 34% between the 3rd and 5th wk. From the age of 5 wk on, 4VCP was characterized by higher blood flow rates than LVCP. Cerebral cortical blood flow gradually increased between the 2nd and 5th wk. There was no difference in cortical blood flow between 5-wk-old and adult animals. The changes in choroidal blood flow likely represent a continuing adjustment of the choroidal vascular system to steadily increasing secretory capabilities of the maturing choroidal epithelium.

scholarly journals Bexarotene Exerts Protective Effects Through Modulation of the Cerebral Vascular Smooth Muscle Cell Phenotypic Transformation by Regulating PPARγ/FLAP/LTB4 After Subarachnoid Hemorrhage in Rats

2019 ◽  
Vol 28 (9-10) ◽  
pp. 1161-1172 ◽  
Author(s):  
Zhaosi Zhang ◽  
Guosheng Zhao ◽  
Liu Liu ◽  
Junchi He ◽  
Rami Darwazeh ◽  
...  
Keyword(s):  
Blood Flow ◽  
Smooth Muscle ◽  
Subarachnoid Hemorrhage ◽  
Vascular Smooth Muscle ◽  
Neurological Impairment ◽  
Peroxisome Proliferator ◽  
Protective Effects ◽  
Cortical Blood Flow ◽  
Phenotypic Transformation ◽  
Cerebral Cortical Blood Flow

Vascular smooth muscle cells (VSMCs) play an important role after a subarachnoid hemorrhage (SAH). The changes in VSMCs following bexarotene treatment after SAH are unknown. In the present study, neurological impairment, decreased cerebral cortical blood flow and transformation of cerebral VSMCs from a contractile to a synthetic phenotype were observed after SAH. Bexarotene reduced neurological impairment, improved cerebral cortical blood flow, inhibited VSMC phenotypic transformation and suppressed the expression of 5-lipoxygenase-activating protein (FLAP) and leukotriene B4 (LTB4), which was partly reversed by GW9662, an inhibitor of peroxisome proliferator-activated receptor gamma (PPARγ). Mechanistically, sh-PPARγ-mediated phenotypic transformation of VSMCs was partially suppressed by MK886, an antagonist of FLAP. Therefore, we conclude that bexarotene reduced neurological impairment, improved cerebral cortical blood flow and inhibited the VSMC phenotypic transformation after SAH, which was achieved by activating PPARγ-mediated inhibition of FLAP/LTB4 in VSMCs

Neuropeptide Y in the Human Circle of Willis and Its Effect on Cerebral Cortical Blood Flow

1984 ◽  
Vol 67 (s9) ◽  
pp. 19P-19P
Author(s):  
J M Allen ◽  
F Schon ◽  
N Todd ◽  
J C Yeats ◽  
H A Crockard ◽  
...  
Keyword(s):  
Blood Flow ◽  
Neuropeptide Y ◽  
Circle Of Willis ◽  
Cortical Blood Flow ◽  
Cerebral Cortical Blood Flow

scholarly journals Cerebral Cortical Blood Flow and Oxygen Metabolism in Normocythemic Hyperviscous Newborn Piglets

1988 ◽  
Vol 24 (4) ◽  
pp. 486-489 ◽  
Author(s):  
Marshall Goldstein ◽  
Barbara S Stonestreet ◽  
Benjamin S Brann ◽  
O H William
Keyword(s):  
Blood Flow ◽  
Oxygen Metabolism ◽  
Cortical Blood Flow ◽  
Newborn Piglets ◽  
Cerebral Cortical Blood Flow

Cervical spinal cord stimulation increases cerebral cortical blood flow in an experimental cerebral vasospasm model

2004 ◽  
Vol 147 (1) ◽  
pp. 79-84 ◽  
Author(s):  
Ö. Karadağ ◽  
E. Eroğlu ◽  
M. Gürelik ◽  
H. M. Göksel ◽  
E. Kılıç ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Blood Flow ◽  
Cerebral Vasospasm ◽  
Spinal Cord Stimulation ◽  
Cervical Spinal Cord ◽  
Cortical Blood Flow ◽  
Cerebral Cortical Blood Flow
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