The potential role of spinal cord cyclooxygenase-2 in the development of Freund's complete adjuvant-induced changes in hyperalgesia and allodynia

Neuroscience ◽  
1997 ◽  
Vol 78 (3) ◽  
pp. 843-850 ◽  
Author(s):  
C.H Hay ◽  
M.A Trevethick ◽  
A Wheeldon ◽  
J.S Bowers ◽  
J.S De Belleroche
Author(s):  
A. Kawaoi

Numbers of immunological approach have been made to the amyloidosis through the variety of predisposing human diseases and the experimentally induced animals by the greater number of agents. The results suggest an important role of impaired immunity involving both humoral and cell-mediated aspects.Recently the author has succeeded in producing amyloidosis in the rabbits and mice by the injections of immune complex of heat denatured DNA.The aim of this report is to demonstrate the details of the ultrastructure of the amyloidosis induced by heterologous insoluble immune complex. Eleven of twelve mice, dd strain, subcutaneously injected twice a week with Freund's complete adjuvant and four of seven animals intraperitonially injected developed systemic amyloidosis two months later from the initial injections. The spleens were electron microscopically observed.


1998 ◽  
Vol 62 (2) ◽  
pp. 228-235 ◽  
Author(s):  
Janice L Arruda ◽  
Raymond W Colburn ◽  
Amy J Rickman ◽  
Maria D Rutkowski ◽  
Joyce A DeLeo

Spinal Cord ◽  
2013 ◽  
Vol 51 (9) ◽  
pp. 656-662 ◽  
Author(s):  
T Lam ◽  
Z Chen ◽  
M M Sayed-Ahmed ◽  
A Krassioukov ◽  
A A Al-Yahya

Author(s):  
Laverne D. Gugino ◽  
Rafael Romero ◽  
Marcella Rameriz ◽  
Marc E. Richardson ◽  
Linda S. Aglio

Two stimulation approaches developed for selectively exciting descending motor pathways are, transcranial electrical (TES) and transcranial magnetic (TMS) stimulation. This article highlights the comparison between electrical and magnetic transcranial stimulation. Magnetic stimulation is relatively painless; therefore it is the more preferred technique. The article reviews the use of TMS for monitoring the functional integrity of the descending motor systems during surgery and discusses the potential role of TMS in the preoperative period for conscious patients planning to undergo neurosurgical procedures involving the cerebral cortex. Selective monitoring of spinal cord motor function involves acquisition of TMS-induced epidural and/or myogenic responses. As patients are generally given anesthesia before spinal cord surgeries, this article discusses the effect of general anesthetic agents on the myogenic responses.


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