Determination of serum and plasma concentrations of retinol using high-performance liquid chromatography

1984 ◽  
Vol 311 ◽  
pp. 239-248 ◽  
Author(s):  
David W. Nierenberg
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Plasma Concentrations

Determination of cocaine concentrations in plasma by high-performance liquid chromatography

1990 ◽  
Vol 36 (8) ◽  
pp. 1436-1439 ◽  
Author(s):  
P Jatlow ◽  
H Nadim
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Plasma Concentrations ◽  
Internal Standard ◽  
Reversed Phase ◽  
Dilute Acid ◽  
Nitrogen Detection ◽  
Chromatographic Procedure

Abstract We describe a procedure for measuring concentrations of cocaine in plasma by reversed-phase high-performance liquid chromatography, with ion-pairing. The procedure involves solvent extraction followed by back-extraction with dilute acid. The n-propyl ester of benzoylecgonine is used as an internal standard. An evaporation step is not required, and concentrations as low as 5 micrograms/L can be quantified. Plasma concentrations of cocaine determined by high-performance liquid chromatography correlated well with those determined by a previously reported gas-chromatographic procedure with nitrogen detection.

Sign in / Sign up

Export Citation Format

Share Document