scholarly journals Metanalysis of antiarrhythmic drugs for conversion of atrial fibrillation and the maintenance of sinus rhythm: Combining efficacy and adverse effects

2003 ◽  
Vol 41 (6) ◽  
pp. 536 ◽  
Author(s):  
Leonardo Tamariz ◽  
Robert McNamara ◽  
Eric Bass
1990 ◽  
Vol 16 (7) ◽  
pp. 1722-1727 ◽  
Author(s):  
Maarten J. Suttorp ◽  
J.Herre Kingma ◽  
Emile R. Jessurun ◽  
Loraine Lie-A-Huen ◽  
Norbert M. Van Hemel ◽  
...  

2021 ◽  
Vol 11 (3) ◽  
pp. 173-185
Author(s):  
G. A. Ignatenko ◽  
G. G. Taradin ◽  
N. T. Vatutin ◽  
A. A. Kaluga ◽  
Yu. D. Kostyamin

The current information about features of atrial fibrillation in patients with hypertrophic cardiomyopathy is presented in this review. The data about prevalence, pathogenesis and its various complications in these patients are disclosed. The article contains updated clinical recommendations of authoritative medical societies on the discussing problem. There is detailed discussion of risk factors of atrial fibrillation onset in setting of hypertrophic cardiomyopathy with demonstration of results of different studies concerning to investigation of relationship between risk factors and probability of the arrhythmia development. There is description of detection methods, clinical manifestations, and the course of atrial fibrillation in patients with hypertrophic cardiomyopathy. The contemporary literature data are presented regarding to the management of patients with atrial fibrillation with use of anticoagulants, antiarrhythmic drugs, indications for performing of radiofrequency ablation and results of studies concerning long-term efficacy of such procedure are demonstrated. The discussion on the management of the patients in cases of sinus rhythm restoration or maintenance failure is described.


Author(s):  
Mazhar Warraich ◽  
Christina Peter ◽  
Mahmood Ahmad ◽  
Shazaib Sheikh ◽  
George R Abraham ◽  
...  

2001 ◽  
Vol 6 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Eduardo Corrêa Barbosa ◽  
Paulo Roberto Benchimol Barbosa ◽  
Paulo Ginefra ◽  
Alfredo Bomfim ◽  
Silvia Helena Cardoso Boghossian ◽  
...  

2021 ◽  
Vol 63 (1) ◽  
pp. 1-7
Author(s):  
AMAR Talib AL-HAMDI ◽  
Azad J. Ali

Background: Atrial fibrillation is the most frequent cardiac arrhythmia encountered in general medicine and cardiology practice. Synchronized direct current shock is a known safe and effective procedure to revert long standing persistent atrial fibrillation into sinus rhythm. Patients and Methods: Patients with long-standing atrial fibrillation who were seen at the author’s private clinic and Al-Hassani Heart Center in Sulaimanya from April 2018 to December 2020 were chosen for rhythm control subjected to synchronized direct current cardioversion under heavy sedation applying a modified anterolateral paddles position with 200J and 300J successively according to the reversion dose required. Objectives: The Objective of current study was to assess the efficacy of synchronized direct current shock in reverting long-standing persistent atrial fibrillation into sinus rhythm and recognizing factors that help in achieving high success rate. Results: In this case series study 61 patients were included thirty-one males 30 females The success rate was 89%. Even patients with atrial fibrillation duration more than 2 years showed a success rate of 84%. The recurrence rate of atrial fibrillation was 30% within a follow up period of one month to 2 years. The modified paddles position has helped in achieving high reversion rate where success increased from 62% to 85% and failure rate decreased from 38% to 15%. The shock dose needed for reversion ranged from 200J to 300 J.  There was no correlation between the needed dose for reversion and body weight where patients with body weight of 71-80kg, more than 80% reverted with 200J. Pre shock antiarrhythmic drugs did not facilitate the conversion, the reversion rate in patients with or without antiarrhythmic drugs were 85% and 82% successively.  No per procedure complications were seen.  Conclusion: Electrical cardioversion of atrial fibrillation with modified paddles position is a safe, effective and smooth procedure with significantly high success rate and very low incidence of complications even with very long-standing atrial fibrillation.


ESC CardioMed ◽  
2018 ◽  
pp. 187-195
Author(s):  
Federico Guerra ◽  
Alessandro Capucci

Antiarrhythmic drugs are the cornerstone of supraventricular and ventricular arrhythmias therapy. Despite the increasing interest in invasive and ablative approaches to treating many arrhythmias, such as atrial fibrillation and ventricular tachycardia, antiarrhythmic drugs are still widely used for both acute management and chronic prophylaxis. Unfortunately, many antiarrhythmic drugs currently available have a narrow therapeutic window and many issues regarding potential serious adverse effects, proarrhythmic properties, and multiorgan toxicity. The current Vaughan Williams classification of antiarrhythmic drugs is shown in a table. The aim this chapter is to provide basic information regarding the most used compounds in clinical practice.


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