scholarly journals 1002-82 Impact of body mass index on outcomes after primary angioplasty in acute myocardial infarction: The obesity paradox

2004 ◽  
Vol 43 (5) ◽  
pp. A244 ◽  
Author(s):  
Eugenia Nikolsky ◽  
Roxana Mehran ◽  
Alexandra J Lansky ◽  
Cindy L Grines ◽  
David A Cox ◽  
...  
Medicina ◽  
2021 ◽  
Vol 57 (9) ◽  
pp. 926
Author(s):  
Sri Harsha Patlolla ◽  
Gayathri Gurumurthy ◽  
Pranathi R. Sundaragiri ◽  
Wisit Cheungpasitporn ◽  
Saraschandra Vallabhajosyula

Background and Objectives: Contemporary data on the prevalence, management and outcomes of acute myocardial infarction (AMI) in relation to body mass index (BMI) are limited. Materials and Methods: Using the National Inpatient Sample from 2008 through 2017, we identified adult AMI hospitalizations and categorized them into underweight (BMI < 19.9 kg/m2), normal BMI and overweight/obese (BMI > 24.9 kg/m2) groups. We evaluated in-hospital mortality, utilization of cardiac procedures and resource utilization among these groups. Results: Among 6,089,979 admissions for AMI, 38,070 (0.6%) were underweight, 5,094,721 (83.7%) had normal BMI, and 957,188 (15.7%) were overweight or obese. Over the study period, an increase in the prevalence of AMI was observed in underweight and overweight/obese admissions. Underweight AMI admissions were, on average, older, with higher comorbidity, whereas overweight/obese admissions were younger and had lower comorbidity. In comparison to the normal BMI and overweight/obese categories, significantly lower use of coronary angiography (62.3% vs. 74.6% vs. 37.9%) and PCI (40.8% vs. 47.7% vs. 19.6%) was observed in underweight admissions (all p < 0.001). The underweight category was associated with significantly higher in-hospital mortality (10.0% vs. 5.5%; OR 1.23 (95% CI 1.18–1.27), p < 0.001), whereas being overweight/obese was associated with significantly lower in-hospital mortality compared to normal BMI admissions (3.1% vs. 5.5%; OR 0.73 (95% CI 0.72–0.74), p < 0.001). Underweight AMI admissions had longer lengths of in-hospital stay with frequent discharges to skilled nursing facilities, while overweight/obese admissions had higher hospitalization costs. Conclusions: In-hospital management and outcomes of AMI vary by BMI. Underweight status was associated with worse outcomes, whereas the obesity paradox was apparent, with better outcomes for overweight/obese admissions.


2011 ◽  
Vol 13 (3) ◽  
pp. 123-128 ◽  
Author(s):  
Ana Teresa Timóteo ◽  
Ruben Ramos ◽  
Alexandra Toste ◽  
José Alberto Oliveira ◽  
Maria Lurdes Ferreira ◽  
...  

2006 ◽  
Vol 151 (1) ◽  
pp. 168-175 ◽  
Author(s):  
Eugenia Nikolsky ◽  
Gregg W. Stone ◽  
Cindy L. Grines ◽  
David A. Cox ◽  
Eulogio Garcia ◽  
...  

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
D.W Kim

Abstract Background Beneficial effects of overweight and obesity on mortality after acute myocardial infarction (AMI) have been described as “Body Mass Index (BMI) paradox”. However, the effects of BMI is still on debate. We analyzed the association between BMI and 1-year major cardiocerebrovascular events (MACCE) after AMI. Methods and findings Among 13,104 AMI patients registered in an Institute of Health in Korea between November 2011 and December 2015, 10,568 patients who eligible for this study were classified into 3 groups according to BMI (Group I; &lt;22 kg/m2, 22 ≤ Group II &lt;26 kg/m2, Group III; ≥26 kg/m2). The primary end point was a composite of cardiac death (CD), myocardial infarction (MI), target vessel revascularization (TVR), and cerebrovascular events at 1 year. Over the median follow-up of 12 months, the composite of primary end point occurred more frequently in the Group I patients than in the Group III patients (primary endpoint: adjusted hazard ratio [aHR], 1.290; 95% confidence interval [CI] 1.024 to 1.625, p=0.031). Especially, cardiac death in MACCE components played a major role in this effect (aHR, 1.548; 95% confidence interval [CI] 1.128 to 2.124, p=0.007). Conclusions Higher BMI appeared to be good prognostic factor on 1-year MACCE after AMI. This result suggests that higher BMI or obesity might confer a protective advantage over the life-quality after AMI. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): Research of Korea Centers for Disease Control and Prevention and the Korea Health Technology R&D Project, Ministry of Health & Welfare (HI13C1527), Republic of Korea.


PLoS ONE ◽  
2019 ◽  
Vol 14 (6) ◽  
pp. e0217525 ◽  
Author(s):  
Dae-Won Kim ◽  
Sung-Ho Her ◽  
Ha Wook Park ◽  
Mahn-Won Park ◽  
Kiyuk Chang ◽  
...  

2019 ◽  
Vol 31 (4) ◽  
pp. 290-291
Author(s):  
Ghada Shalaby ◽  
Waleed Mahmoud ◽  
Asmaa Alsolami ◽  
Mohannad AlHazmi ◽  
Reem Alhassani ◽  
...  

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